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RECORD NUMBER: 16 OF 44

Main Title Genetic Activity Profiles in the Testing and Evaluation of Chemical Mixtures, June 1990.
Author Waters, M. D.; Claxton, L. D.; Stack, H. F.; Brady, A. L.; Graedel., T. E.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. ;A.T. and T. Bell Labs., Murray Hill, NJ.
Publisher c1990
Year Published 1990
Report Number EPA/600/J-90/166;
Stock Number PB91-115840
Subjects Toxicology; Graphs(Charts); Bioassay; Salmonella typhimurium; Reprints; Mutagenicity tests; Genetic Activity Profile(GAP); Toxic substances; Data bases; Dose-response relationships
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB91-115840 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/04/1991
Collation 20p
Abstract Some knowledge of the potential genetic activity of a complex environmental mixture may be gained from an assessment of the genetic activity of its component chemicals. The expanded Genetic Activity Profile (GAP) data base provides a computer-generated graphic representation of genetic bioassay data as a function of dose of the substance tested. In addition, the Atmospheric Chemical Compound (ACC) data base contains information on chemical structures, properties, detection methods and sources of chemicals found in ambient air. Using the combined data bases, information on the quantity of an individual chemical present within a mixture or fraction of a mixture may be related to the quantity (lowest effective dose, LED) of the chemical required to demonstrate a positive response in one or more genetic bioassays. (Copyright (c) 1990 Wiley-Liss, Inc.)
Supplementary Notes Pub. in Teratogenesis, Carcinogenesis, and Mutagenesis, v10 p147-164 1990. See also PB90-112780. Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC., and A.T. and T. Bell Labs., Murray Hill, NJ.
NTIS Title Notes Journal article.
Title Annotations Reprint: Genetic Activity Profiles in the Testing and Evaluation of Chemical Mixtures, June 1990.
Category Codes 57Y; 57F; 68G
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Control Number 101123286
Cataloging Source NTIS/MT
Origin NTIS
Type CAT