OLS : Record

RECORD NUMBER: 11 OF 44

Main Title Genetic Activity Profile (GAP) Data Base.
Author Waters, M. D.; Stack, H. F.; Jackson, M. A.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Publisher 11 Jan 91
Year Published 1991
Report Number EPA/600/D-91/049;
Stock Number PB91-177014
Subjects Mutagens; Carcinogens; Test methods; Microcomputers; Dose-response relationships; Comparative study; Mutagenicity tests; Carcinogenicity tests; Data bases; Genetic Activity Profile Database; Weight-of-evidence ranking
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB91-177014 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 09/04/1991
Collation 21p
Abstract The report provides an update on the status of the genetic activity profile (GAP) data base which now consists of more than 400 chemicals. The data base is available in a personal computer software package which is described in the report. The report also describes several of the ways in which the data base and associated methodology are currently being utilized by international and U.S. governmental agencies and by industry. These include: (I) Evaluation of genetic and related effects of suspected human carcinogens, (II) Comparative evaluation of genetic activity profiles using computer-based profile matching techniques, (III) Testing and evaluation of complex mixtures, and (IV) Weight-of-evidence ranking schemes. The fundamental techniques and computer programs devised for the GAP data base may be used to develop similar data bases in genetic toxicology and in other disciplines.
Supplementary Notes Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Category Codes 57Y; 57F
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Control Number 116430086
Cataloging Source NTIS/MT
Origin NTIS
Type CAT