OLS : Record


Main Title Characteristics of the U.S. EPA's Office of Pesticide Programs' Toxicity Information Databases.
Author Dearfield, K. L.; Quest, J. A.; Whiting, R. J.; Stack, H. F.; Waters, M. D.;
CORP Author Environmental Health Research and Testing, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-92/191;
Stock Number PB92-188978
Subjects Data bases; Pesticides; Toxicity; Health hazards; Mutation; Carcinogens; Peer review; Mutagens; Reprints;
Library   Call Number Additional Info Location Date Modified
NTIS PB92-188978 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/22/1992
Collation 6p
Abstract The United States Environmental Protection Agency's (USEPA's) Office of Pesticide Programs (OPP) requires that data from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. Once these data are submitted, they are entered into various toxicity data bases. The studies themselves are cataloged in an archival data base to allow retrieval of the study for review. Reviews of toxicity studies are then placed into a separate data base which can be retrieved to support a regulatory position. Toxicity information for health effects other than cancer and gene mutations from chronic exposure is reviewed through a reference dose (RfD) approach and these decisions and supporting data are entered into an RfD data base. Carcinogenicity data are reviewed by a Peer Review Process and these decisions will be entered into a newly developed data base to show the regulatory decision with supporting data. The mutagenicity data are reviewed and acceptable data are entered into the Genetic Activity Profile system to catalog and display the submitted information. These data bases contain the information used for hazard evaluations as part of the OPP review of pesticide chemicals.
Supplementary Notes Pub. in Environmental Health Perspectives, v96 p53-56 Nov 91. Sponsored by Health Effects Research Lab., Research Triangle Park, NC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Characteristics of the U.S. EPA's Office of Pesticide Programs' Toxicity Information Databases.
Category Codes 68E; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/10
Document Type NT
Control Number 220521521
Cataloging Source NTIS/MT
Origin NTIS
Type CAT