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RECORD NUMBER: 6 OF 12

Main Title Teratologic Evaluation of 2,3,4,6-Tetrachlorophenol (CAS No. 58-90-2) Administered to CD Rats on Gestational Days 6 through 15. Final Report.
Author George, J. D.; Price, C. J.; Sleet, R. B.; Marr, M. C.; Segal, S. A.;
CORP Author Dynamac Corp., Rockville, MD. ;Research Triangle Inst., Research Triangle Park, NC.;Environmental Protection Agency, Washington, DC. Office of Solid Waste.
Year Published 1987
Report Number EPA-68-01-7366; EPA/530/SW-88/017A;
Stock Number PB88-176151
Subjects Toxicology; Rats; Laboratory animals; Dosage; Bioassay; Pregnancy; Teratogenesis; CAS 58-90-2; Tetrachlorophenol
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB88-176151 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 104p
Abstract 2,3,4,6-Tetrachlorophenol (TCP) was administered by gavage in olive oil to timed-pregnant CD rats at doses of 0, 25, 100, or 200 mg/kg/day on gestational days (gd) 6-15. No significant maternal effects were noted at 25 to 100 mg/kg/day TCP. At 200 mg/kg/day TCP, corrected maternal weight gain was significantly depressed below controls. During the post-treatment period, all TCP-exposed groups consumed significantly more food than the control group. Embryo/fetal growth and prenatal viability were not adversely affected by TCP exposure, nor was there any definitive evidence of an effect of TCP upon fetal morphological development.
Supplementary Notes See also PB88-176169. Prepared in cooperation with Research Triangle Inst., Research Triangle Park, NC. Sponsored by Environmental Protection Agency, Washington, DC. Office of Solid Waste.
PUB Date Free Form 21 Aug 87
Category Codes 57Y#; 57E; 68G#
NTIS Prices PC A06/MF A01
Primary Description 200/01
Document Type NT
Control Number 811328167
Cataloging Source NTIS/MT
Origin NTIS
Type CAT