OLS : Record


Main Title Increase in Glial Fibrillary Acidic Protein Follows Brain Hyperthermia in Rats.
Author Miller, D. B.; Blackman, C. F.; O'Callaghan, J. P.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div.
Year Published 1987
Report Number EPA/600/J-87/169;
Stock Number PB88-159611
Subjects Hyperthermia; Protein; Rats; Laboratory animals; Reprints; Acidic protein; Brain injury; GFAP
Library   Call Number Additional Info Location Date Modified
NTIS PB88-159611 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 6p
Abstract Previously, the authors have demonstrated that an increase in the astrocyte-associated protein, glial fibrillary acidic protein (GFAP), accompanies brain injury induced by a variety of chemical insults. In the present study the authors examined the effects of microwave-induced hyperthermia of the CNS on the concentration of GFAP in several brain regions of the Long-Evans rat. Irradiation resulted in a time-related increase in GFAP in olfactory bulbs and cortex, areas of maximum heating. The increase in GFAP following a brain temperature increase suggests that heating of brain tissue may be sufficient to provoke an injury response comparable to that induced by chemical and physical insult.
Supplementary Notes Pub. in Brain Research 415, p371-374 1987.
NTIS Title Notes Journal article.
Title Annotations Reprint: Increase in Glial Fibrillary Acidic Protein Follows Brain Hyperthermia in Rats.
PUB Date Free Form 1987
Category Codes 57B
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Control Number 809820280
Cataloging Source NTIS/MT
Origin NTIS
Type CAT