| Main Title |
Increase in Glial Fibrillary Acidic Protein Follows Brain Hyperthermia in Rats. |
| Author |
Miller, D. B.;
Blackman, C. F.;
O'Callaghan, J. P.;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div. |
| Year Published |
1987 |
| Report Number |
EPA/600/J-87/169; |
| Stock Number |
PB88-159611 |
| Subjects |
Hyperthermia;
Protein;
Rats;
Laboratory animals;
Reprints;
Acidic protein;
Brain injury;
GFAP
|
| Holdings |
| Library |
|
Call Number |
Additional Info |
Location |
Date Modified |
| NTIS |
|
PB88-159611 |
Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. |
NTIS |
06/21/1988 |
|
| Collation |
6p |
| Abstract |
Previously, the authors have demonstrated that an increase in the astrocyte-associated protein, glial fibrillary acidic protein (GFAP), accompanies brain injury induced by a variety of chemical insults. In the present study the authors examined the effects of microwave-induced hyperthermia of the CNS on the concentration of GFAP in several brain regions of the Long-Evans rat. Irradiation resulted in a time-related increase in GFAP in olfactory bulbs and cortex, areas of maximum heating. The increase in GFAP following a brain temperature increase suggests that heating of brain tissue may be sufficient to provoke an injury response comparable to that induced by chemical and physical insult. |
| Supplementary Notes |
Pub. in Brain Research 415, p371-374 1987. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Increase in Glial Fibrillary Acidic Protein Follows Brain Hyperthermia in Rats. |
| PUB Date Free Form |
1987 |
| Category Codes |
57B |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Control Number |
809820280 |
| Cataloging Source |
NTIS/MT |
| Origin |
NTIS |
| Type |
CAT |
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