OLS : Record

RECORD NUMBER: 32 OF 49

Main Title New Techniques for Imaging and Analyzing Lung Tissue.
Author Roggli, V. L.; Ingram, P.; Linton, R. W.; Gutknecht, W. F.; Mastin, P.;
CORP Author Duke Univ. Medical Center, Durham, NC. Dept. of Pathology. ;Research Triangle Inst., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-R-805460 ;EPA-R-807560; EPA/600/J-84/124;
Stock Number PB85-114080
Subjects Lung; Imaging; Medical equipment; Tissues(Biology); Pathology; Toxicology; Exposure; Reprints; Toxic substances
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB85-114080 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 24p
Abstract The recent technological revolution in the field of imaging techniques has provided pathologists and toxicologists with an expanding repertoire of analytical techniques for studying the interaction between the lung and the various exogenous materials to which it is exposed. Analytical problems requiring elemental sensitivity or specificity beyond the range of that offered by conventional scanning electron microscopy and energy dispersive X-ray analysis are particularly appropriate for the application of these newer techniques. Electron energy loss spectrometry, Auger electron spectroscopy, secondary ion mass spectrometry, and laser microprobe mass analysis each offer unique advantages in this regard, but also possess their own limitations and disadvantages. Diffraction techniques provide crystalline structural information available through no other means. Bulk chemical techniques provide useful cross-checks on the data obtained by microanalytical approaches. It is the purpose of this review to summerize themethodology of these techniques, acknowledge situations in which they have been used in addressing problems in pulmonary toxicology, and comment on the relative advantages and disadvantages of each approach.
Supplementary Notes Prepared in cooperation with Research Triangle Inst., Research Triangle Park, NC., and North Carolina Univ. at Chapel Hill. Dept. of Chemistry.
Availability Notes Pub. in Environmental Health Perspectives, v56 p163-183 1984.
NTIS Title Notes Journal article.
Title Annotations Reprint: New Techniques for Imaging and Analyzing Lung Tissue.
PUB Date Free Form c1984
Category Codes 6E; 95C; 57E; 68A
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Control Number 503221765
Cataloging Source NTIS/MT
Origin NTIS
Type CAT