||Interaction of Inorganic Mercury Salts with Model and Red Cell Membranes: Importance of Lipid Binding Sites.
Allis., J. W.;
||Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div. ;French Foreign Ministry Lavoisier Program, Paris (France),
Mercury inorganic compounds;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The effect of two mercury salts, HgCl2 and Hg(NO3)2, on the thermotropic properties of phosphatidylserine (PS) model membranes and sonicated rat red cell membranes was investigated by fluorescence polarization. Both Hg(II) salts abolished the phase transition and decreased the membrane fluidity by interacting with PS. These results indicate that besides protein thiol groups, Hg(II)-lipid binding sites play an important role in the interaction of Hg(II) with red cell membranes that is qualitatively different from Hg(II) binding to protein thiol groups. (Copyright (c) 1993 Elsevier Scientific Publishers Ireland Ltd.)
||Pub. in Chemico-Biologic Interactions v88 n1 p71-87 Oct 93. Prepared in cooperation with French Foreign Ministry Lavoisier Program, Paris (France),.
|NTIS Title Notes
||Reprint: Interaction of Inorganic Mercury Salts with Model and Red Cell Membranes: Importance of Lipid Binding Sites.
||57Y; 57B; 57F
||PC A03/MF A01