OLS : Record


Main Title Bortezomib in the Treatment of Multiple Myeloma [electronic resource] /
Author Ghobrial, Irene M.
Publisher Springer Basel : Imprint: Springer,
Place Published Basel
Year Published 2011
Subject Added Ent Medicine.; Oncology.; Toxicology.; Cytology.
Internet Access
Description Access URL
Library   Call Number Additional Info Location Date Modified
Collation VIII, 179p. online resource.
Contents Notes Multiple Myeloma (MM) is the second most common type of blood cancer, resulting from an overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent the degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon the suppression of proapoptotic pathways. This monograph on bortezomib is a valuable source of information for researchers and clinicians from the fields of oncology and pharmacology, working either in academia or the pharmaceutical industry.
Author Added Ent
Richardson, Paul G.;
Anderson, Kenneth C.
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Milestones in Drug Therapy
Host Item Entry Springer eBooks
PUB Date Free Form 2011
Series Title Untraced Milestones in Drug Therapy
BIB Level m
Medium computer
ISBN 9783764389482
OCLC Time Stamp 20130725202425
Cataloging Source OCLC/T
Language eng
OCLC Rec Leader 02500nam a22004935i 45