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OLS : Record

RECORD NUMBER: 29 OF 8451

Main Title 5,7-Dihydroxytryptamine Injections Increase Glial Fibrillary Acidic Protein in the Hypothalamus of Adult Rats.
Author Frankfurt, M.; O'Callaghan, J.; Beaudet, A.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. ;Rockefeller Univ., New York. Lab. of Neuroendocrinology. ;Montreal Neurological Inst. (Quebec). Neuroanatomy Lab.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/020;
Stock Number PB92-143924
Subjects Glial fibrillary acidic protein; Hypothalamus; 5-7-dihydroxytryptamine; Rats; Astrocytes; Serotonin; Radioimmunoassay; Immunohistochemistry; Reprints;
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB92-143924 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/28/1992
Collation 5p
Abstract The distribution and level of glial fibrillary acidic protein (GFAP) were determined in the adult rat hypothalamus following axotomy of serotonin (5-HT) neurons. Seven days after unilateral intrahypothalamic injection of the 5-HT neurotoxic, 5,7-dihydroxytryptamine, there was a marked increase in the number of GFAP-labelled astrocytes in the ipsilateral hypothalamus of 5,7-DHT-treated as compared to sham-treated rats. Measurement of GFAP levels demonstrated a significant increase on the ipsilateral side of 5,7-DHT-treated rats as compared to sham-treated rats.
Supplementary Notes Pub. in Brain Research, v549 n1 p138-140 May 91. See also PB91-117077. Prepared in cooperation with Rockefeller Univ., New York. Lab. of Neuroendocrinology, and Montreal Neurological Inst. (Quebec). Neuroanatomy Lab.
NTIS Title Notes Journal article.
Title Annotations Reprint: 5,7-Dihydroxytryptamine Injections Increase Glial Fibrillary Acidic Protein in the Hypothalamus of Adult Rats.
Category Codes 57Y; 57F
NTIS Prices PC A01/MF A01
Primary Description 600/10
Document Type NT
Control Number 208728750
Cataloging Source NTIS/MT
Origin NTIS
Type CAT


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