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RECORD NUMBER: 26 OF 1033

Main Title Addendum to the health assessment document for dichloromethane (methylene chloride) : updated carcinogenicity assessment of dichloromethane (methylene chloride).
Author Bayard, S.; Bayliss, D.; Davidson, I.; Fowle, J.; Greenberg, M.
CORP Author United States. Environmental Protection Agency. Office of Health and Environmental Assessment.
Publisher Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency,
Place Published Washington, D.C. :
Year Published 1985
Report Number EPA 600/8-82/004 FF
Stock Number PB85-191559
OCLC Number 13448023
Subjects Dichloromethane--Toxicology; Air--Pollution--Physiological effect; Hazardous materials; Industrial hygiene; Toxicology; Environmental surveys; Chloromethanes; Assessments; Exposure; Water pollution; Carcinogens; Air pollution; Surface waters; Potable water; Mutagens; Epidemiology; Laboratory animals; Methane/dichloro; Water pollution effects(Humans); Occupational safety and health; Toxic substances; Environmental health; Cancer; Water pollution effects(Animals)
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=300016N4.txt
http://nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=2000BF0O.txt
Holdings
Library   Call Number Additional Info Location Date Modified
EIAD EPA/600/8-82/004F Region 2 Library/New York,NY 05/23/1997
EJAD EPA 600/8-82-004FF Region 3 Library/Philadelphia, PA 10/29/1993
EJED EPA 600/8-82-004ff OCSPP Chemical Library/Washington,DC 01/01/1988
EKAM EPA/600/8-82/004 F Region 4 Library/Atlanta,GA 09/01/1995
ELBD EPA/600/8-82/004FF AWBERC Library/Cincinnati,OH 12/20/1996
NTIS PB85-191559 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation vii, 113 p. : ill. ; 28 cm.
Abstract Dichloromethane is used extensively in commercial and industrial solvent applications. The background atmospheric concentration is about 35 ppt. In surface water and drinking water, measured concentrations generally have been in the low parts per billion range. Available data suggest that DCM is biodegradable and has low aquatic toxicity to aquatic organisms. The weight of evidence from the available literature indicates that adverse toxicologic (non-genotoxic) effects in humans are unlikely to occur at ambient air or water levels found or expected in the general environment. Available evidence suggests that the teratogenic potential of DCM for humans is minimal. The weight of evidence with respect to mutagenic potential shows that DCM is capable of causing gene mutations and has the potential to cause such effects in exposed human cells. With regard to cancer, the weight of evidence from experimental animal studies is limited. When the absence of epidemiological evidence is considered with the limited animal evidence, the overall evaluation of DCM using the criteria of the International Agency for Research on Cancer is a Group 3 chemical in that it cannot be classified as to its carcinogenic potential for humans.
Notes "Final report." Distributed to depository libraries in microfiche. "September 1985." "EPA/600/8-82/004FF." Bibliography: p. 109-113.
Supplementary Notes Prepared in cooperation with Bowman Gray School of Medicine, Winston-Salem, NC.
Corporate Au Added Ent United States. Environmental Protection Agency. Office of Health and Environmental Assessment.
Alternate Title Health assessment document for dichloromethane (methylene chloride), updated carcinogenicity assessment of dichloromethane (methylene chloride).
PUB Date Free Form {1985}
Ti Tra Differently Health assessment document for dichloromethane (methylene chloride), updated carcinogenicity assessment of dichloromethane (methylene chloride).
NTIS Prices PC A11/MF A01
BIB Level m
Document Type BC
OCLC Time Stamp 20000128151120
Cataloging Source OCLC/T
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 01379nam 2200313Ia 45020


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