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OLS : Record

RECORD NUMBER: 8 OF 5777

Main Title 1,2-butylene Oxide: Skin Sensitization Potential in the Guinea Pig with Cover Letter from Bowman Cm, 2020 dow Center to Timm G, Ots dated 01/23/1984.
CORP Author Dow Chemical Co., Midland, MI. Toxicology Research Lab.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1984
Report Number 40-8475031
Stock Number OTS0507304
Subjects Toxicology; Health effects; Butylene Oxide; Primary Dermal Sensitization; Mammals; Guinea Pigs; Dermal; Toxic substances; Laboratory animals; CAS No 106-88-7
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS OTS0507304 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 8p
Abstract Skin sensitization potential of 1,2- butylene oxide was evaluated in 10 male Hartley albino guinea pigs exposed to 0.1 ml of undiluted test compound 4 times over a 7 day period, followed 2 weeks later by a single challenge exposure. Treatment did not produce signs of sensitization in any of the guinea pigs, whereas 9 of 10 guinea pigs exposed to a positive control solution (0.1 ml of DER 331) exhibited a positive response indicative of sensitization. The authors concluded that the test compound was not a potential human skin sensitizer.
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PUB Date Free Form 1984
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A02/MF A02
Document Type NT
Control Number 028801180
Cataloging Source NTIS/MT
Origin NTIS
Type CAT


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