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OLS : Record

RECORD NUMBER: 12 OF 560

Main Title Acute toxicity testing criteria for chemical substances /
Author Normandy, Mary Janet.; Reynolds, Robert
CORP Author Enviro Control, Inc., Rockville, MD.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher Premanufacturing Review Division, Office of Toxic Substances, U.S. Environmental Protection Agency ; Available from NTIS,
Place Published Washington, D.C. Springfield, Va.
Year Published 1979
Report Number EPA-560/13-79-009
Stock Number PB80-111073
OCLC Number 08421133
Subjects Toxicology; Chemical compounds; Bioassay; Data collection; Tests; Criteria; Procedures; Lethal dosage; Mortality; Inhalation; Ingestion(Biology); Recommendations; Risk; Laboratory animals; Experimental data; Skin(Anatomy); Eye(Anatomy); Exposure; Toxic substances
Subject Added Ent Toxicology--Testing
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=9100BG9B.txt
Holdings
Library   Call Number Additional Info Location Date Modified
EJBD ARCHIVE EPA 560-13-79-009 Headquarters Library/Washington,DC 05/19/2014
EJED EPA-560/13-79-009 OCSPP Chemical Library/Washington,DC 07/30/1999
NTIS PB80-111073 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation v, 36 p. ; 28 cm.
Abstract The report addresses the rationale, considerations, and limitations of acute toxicity testing. General procedures are described for acute tests including lethality studies in oral, dermal, and inhalation toxicity, and irritation studies in dermal and eye toxicity, phototoxicity and skin sensitization. Recommendations are given for the acute toxicity tests which may be used to evaluate the risks associated with the manufacture and processing of chemical substances. Suggested minimum protocols are offered including the choice of test animals, dosage levels, laboratory practices, animal diets, and necropsy requirements. A method is suggested for interpreting the results of these tests and extrapolating to some guidelines for a safety factor in human exposure.
Notes "EPA-560/13-79-009." "PB80-111073." "July 1979." Performing organization Enviro Control, Incorporated. Includes bibliographical references.
Author Added Ent
Reynolds, Robert;
Kamely, Daphne.
Corporate Au Added Ent Enviro Control, inc.
PUB Date Free Form 1979
NTIS Prices PC A03/MF A01
BIB Level m
OCLC Time Stamp 20140515060300
Cataloging Source OCLC/T
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 01280cam 2200337Ia 45020


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