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RECORD NUMBER: 12 OF 41

Main Title Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog.
Author Copeland, M. F.; Cranmer., M. F.;
CORP Author Environmental Protection Agency, Perrine, Fla. Primate and Pesticide Effects Lab.
Year Published 1973
Stock Number PB-279 721
Subjects Insecticides; DDT; Pesticides; Toxicology; Dogs; Enzymes; Liver; Ribosomes; Adrenal gland; Ingestion(Biology); Laboratory animals; Experimental data; Physiological effects; Tables(Data); Tissues(Biology); Distribution; Storage; Adrenal cortex; Herbicides; Reprints; Toxic substances; DDD insecticide; Bioaccumulation
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB-279 721 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Abstract Four male beagle dogs received o,p'-DDT (50 mg/kg/day) in corn oil, administered in gelatin capsules, for 32 days. Four dogs used as controls received only corn oil. The treated dogs maintained body weights comparable to the controls and there were no overt signs of toxicity. The treated dogs showed a decreased eosinopenic response to ACTH after day 16. There was no significant difference in the plasma sodium and potassium concentrations or in the hematocrit before or after ACTH, nor in the 17-hydroxycorticosteroid (17-OHCS) response to ACTH between the treated and control dogs on any of the test days.
Supplementary Notes Pub. in Toxicology and Applied Pharmacology 27, p1-10 1974.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 9, PB-279 718.
Title Annotations Reprint: Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog,
PUB Date Free Form 14 May 73
Category Codes 6T; 57Y; 68G; 68E
NTIS Prices (Order as PB-279 718, MF A01)
Primary Description 500/01
Document Type NT
Control Number 323738871
Cataloging Source NTIS/MT
Origin NTIS
Type CAT