||Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog.
Copeland, M. F.;
Cranmer., M. F.;
||Environmental Protection Agency, Perrine, Fla. Primate and Pesticide Effects Lab.
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Four male beagle dogs received o,p'-DDT (50 mg/kg/day) in corn oil, administered in gelatin capsules, for 32 days. Four dogs used as controls received only corn oil. The treated dogs maintained body weights comparable to the controls and there were no overt signs of toxicity. The treated dogs showed a decreased eosinopenic response to ACTH after day 16. There was no significant difference in the plasma sodium and potassium concentrations or in the hematocrit before or after ACTH, nor in the 17-hydroxycorticosteroid (17-OHCS) response to ACTH between the treated and control dogs on any of the test days.
||Pub. in Toxicology and Applied Pharmacology 27, p1-10 1974.
||Included in the report, Journal Articles on Toxicology. Group 9, PB-279 718.
||Reprint: Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog,
|PUB Date Free Form
||14 May 73
||6T; 57Y; 68G; 68E
||(Order as PB-279 718, MF A01)