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OLS : Record

RECORD NUMBER: 4 OF 5696

Main Title 'Neanthes arenaceodentata' (Polychaeta: Annelida), a Proposed Cytogenetic Model for Marine Genetic Toxicology.
Author Pesch, Gerald G.; Pesch, Carol E.;
CORP Author Environmental Research Lab., Narragansett, RI.
Year Published 1981
Report Number EPA-600/J-80-233 ;ERLN-J132;
Stock Number PB81-184715
Subjects Toxicology; Annelida; Chromosomes; Models; In vivo analysis; Concentration(Composition); Reprints; Neanthes arenaceodentata; Sister chromatid exchange; Mitomycin; Cytogenetics
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB81-184715 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 4p
Abstract Genetic toxicants are present in polluted marine environments and may represent a long-term threat to populations of marine organisms. This paper presents details of an in vivo application of sister chromatid exchange (SCE) analysis to a marine polychaete worm Neanthes arenaceodentata. This species exhibits a dose response to mitomycin C (MMC) at concentrations comparable to those eliciting responses in in vivo mammalian systems. A dose of 5 x 10 to the minus 7th power mol/L MMC increased the rate of SCE from a baseline frequency of 0.14/chromosome to 0.5/chromosome. The chromosomes of N. arenaceodentata may provide a useful model for identifying and studying the effects of genetic toxicants in marine environments.
Supplementary Notes Pub. in Canadian Jnl. of Fisheries and Aquatic Sciences, v37 n8 p1225-1228 1980.
NTIS Title Notes Journal article.
Title Annotations Reprint: 'Neanthes arenaceodentata' (Polychaeta: Annelida), a Proposed Cytogenetic Model for Marine Genetic Toxicology.
PUB Date Free Form Mar 81
Category Codes 6T; 8A; 57Y; 47D
NTIS Prices PC A02/MF A01
Primary Description 600/05
Document Type NT
Control Number 323796022
Cataloging Source NTIS/MT
Origin NTIS
Type CAT


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