OLS : Record

RECORD NUMBER: 14 OF 14

Main Title

Support: Letter from (Confidential) to USEPA regarding an Acute Inhalation Toxicity Study with Chloroalkane, dated 07/23/1996 (Sanitized).

CORP Author

; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.

Year Published

1996

Report Number

8EHQ-0796-13623S

Stock Number

OTS0558497-1

Subjects

Toxicology; Health effects; Toxic substances; Ucar latex 379; Case report; CAS No 50-00-0; CAS No 67-64-1; CAS No 75-07-0; CAS No 108-05-4; CAS No 123-86-4; CAS No 141-78-6; CAS No 7732-18-5; CAS No 25067-01-0

Holdings

Library		Call Number	Additional Info	Location	Date Modified
NTIS		OTS0558497-1	Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.	NTIS	05/12/2010

Collation

26p

Abstract

In an approximate lethal concentration (ALC) study, three groups of six male rats each were exposed nose-only for four hours to vapor concentrations of 0.77, 2.5, at 3.1 mgfL of the test substance in air. No deaths or reportable clinical signs of toxicity were observed in rats exposed to vapors of the test substance in air. In the same study, two additional groups of six male rats each were similarly exposed for four hours to a combined vapor/aerosol concentration of 3.9 or 5.4 mg/L of the test material in air. Fractional mortalities at both exposure concentrations were 3/6. During the vapar/aerosol exposures, mts displayed no alerting response. Rats in the 39 ag/L exposure group displayed head bobbing, splayed legs, and slight palpebral closure. The rats that displayed these clinical signs died during the 14-day post-exposure observation pedod. The rats that died in the 5.4 mg/L exposure group displayed weakness, lethargy, abnormal gait, and irregular respiration.

Supplementary Notes

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Availability Notes

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PUB Date Free Form

24 Jul 1996

Category Codes

57Y; 57U; 68G; 99; 44G

NTIS Prices

PC A03/MF A03

Document Type

Control Number

010500240

Cataloging Source

NTIS/MT

Origin

NTIS

Type

CAT

OLS : Record

RECORD NUMBER: 14 OF 14

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