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OLS : Record

RECORD NUMBER: 25 OF 2484

Main Title Absorption of Lead from Drinking Water with Varying Mineral Content.
Author Miller, R. G.; Greathouse, D.; Bull, R. J.; Doerger, J. U.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/398;
Stock Number PB86-201332
Subjects Lead(Metal); Toxicology; Bioassay; Absorption; Rats; Laboratory animals; Dosage; Heavy metals; Drinking water
Holdings
Library   Call Number Additional Info Location Date Modified
NTIS PB86-201332 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 11p
Abstract Lead (Pb) (200 ppm) was administered via drinking water to rats for nine weeks. In addition, the rats were grouped so that they received 75, 100, 150 and 250% of the minimum daily requirements (MDR) of calcium (Ca), iron (Fe), and magnesium (Mg) as required for normal growth. The exposures were arranged so that no more than one element was varied within the same animal groups, while maintaining 100% of the MDR of all other elements and nutrients. Blood lead analysis were performed at 0, 1, 2, 3, 7, 8, 9 weeks after exposure. Food and water consumptions and body weights were measured each week (0-9). Some gross differences were seen both within and among the groups with respect to milliliters water consumed vs. body weight and grams of food consumed vs. body weight. During the first few weeks of exposure, the mean blood lead in animals fed 75% MDR of Ca, Fe, and Mg at appeared less than those receiving 100% MDR of the corresponding elements. There was a decrease in mean blood lead concentration in animals receiving 150 and 250% of the MDR of Fe at the 7-9 week time period, however, this was probably due to a slight decrease in water consumption during the time period.
Supplementary Notes Pub. in Advances in Modern Environmental Toxicology, v9 ch25 p289-297 1985.
NTIS Title Notes Journal article.
PUB Date Free Form 1985
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Control Number 621322834
Cataloging Source NTIS/MT
Origin NTIS
Type CAT


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