OLS : Record


Main Title Germinomas and Teratoid Siphon Anomalies in Softshell Clams, 'Mya arenaria', Environmentally Exposed to Herbicides.
Author Gardner, G. R.; Yevich, P. P.; Hurst, J.; Thayer, P.; Benyi, S.;
CORP Author Environmental Research Lab., Narragansett, RI. ;Maine State Dept. of Marine Resources, West Boothbay Harbor. ;National Museum of Natural History, Washington, DC.;National Institutes of Health, Bethesda, MD.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/079 ;ERLN-949; NIH-N01-CP-61063;
Stock Number PB91-196592
Subjects Clams; Herbicides; Water pollution effects(Animals); Oil spills; Coastal regions; Maine; Pathology; Chemical analysis; Mesothelioma; Reprints; Germinoma; Clam siphons; D 2-4 herbicide; Mya arenaria; T 2-4-5 herbicide
Library   Call Number Additional Info Location Date Modified
NTIS PB91-196592 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 09/04/1991
Collation 11p
Abstract Seminomas and dysgerminomas are epizootic in softshell clams, Mya arenaria, from three Maine estuaries contaminated with herbicides. The first epizootic was discovered in 22% of clams collected as Searsport near Long Cove Brook and three culverts that conveyed heating oil and jet fuel spilled from a tank farm in 1971. Data from subsequent epizootiological studies and a series of long-term experimental exposures of softshell clams to no. 2 fuel oil, JP-4, andJP-5 jet fuel at the U.S. EPA, Environmental Research Laboratory in Narragansett, Rhode Island, and in the field did not support an etiology by these petroleum products. In the two recent epizootics reported here, the germinomas have been observed in 3% of the softshell clams collected from Roque Bluffs near Machiasport and from 35% of softshell clams collected from Dennysville. Mya collected at Dennysville had pericardial mesotheliomas and teratoid siphon anomalies in addition to gonadal neoplasms. Estuaries at Dennysville had been contaminated by herbicides in a 1979 accidental spray overdrift during aerial application of Tordon 101 to adjacent forests. Further investigation determined widespread use of the herbicides Tordon 101,2,4-D, 2,4,5-T, and other agrochemicals in an extensive forestry and blueberry industry in both the Roque Bluffs and the Dennysville areas. Herbicide applications at Searsport were confirmed for railroad property bordering Long Cove estuary and for Long Cove Brook adjacent to the estuary where a highway department reportedly cleans its spray equipment. Herbicide contamination is the only common denominator identified at all three sites where Mya have been found with gonadal neoplasms.
Supplementary Notes Pub. in Environmental Health Perspectives, v90 p43-51 1991. Prepared in cooperation with Maine State Dept. of Marine Resources, West Boothbay Harbor, and National Museum of Natural History, Washington, DC. Sponsored by National Institutes of Health, Bethesda, MD.
NTIS Title Notes Journal article.
Title Annotations Reprint: Germinomas and Teratoid Siphon Anomalies in Softshell Clams, 'Mya arenaria', Environmentally Exposed to Herbicides.
Category Codes 68D; 68E; 47D
NTIS Prices PC A03/MF A01
Primary Description 600/05
Document Type NT
Control Number 120725019
Cataloging Source NTIS/MT
Origin NTIS
Type CAT