| Main Title |
Armitage-Doll Two-Stage Model: Implications and Extension. |
| Author |
Chen, C. W.;
|
| CORP Author |
Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Publisher |
c1993 |
| Year Published |
1993 |
| Report Number |
EPA/600/J-93/293 ;OHEA-C-462; |
| Stock Number |
PB93-222842 |
| Subjects |
Carcinogens;
Risk assessment;
Mathematical models;
Hazards;
Cancer;
Exposure;
Reprints;
MVK model;
Two-stage models;
ADT model
|
| Holdings |
| Library |
|
Call Number |
Additional Info |
Location |
Date Modified |
| NTIS |
|
PB93-222842 |
Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. |
NTIS |
11/22/1993 |
|
| Collation |
9p |
| Abstract |
The objective of the paper is twofold: (1) to provide insight on the simplified MVK model of carcinogenesis by revealing the relationship between the Armitage-Doll two-stage model (ADT model) and the simplified MVK model; and (2) to extend the ADT model to one with time-varying (piece-wise constant) parameters. It is shown that the simplified MVK model is a special case of the Armitage-Doll two-stage model , and many applications of the simplified MVK model involving intermittent exposures or exposures to different compounds in different time periods can be derived easily from the ADT model with piece-wise constant parameters. The limitations of the ADT model are discussed. (Copyright (c) 1993 Society for Risk Analysis.) |
| Supplementary Notes |
Pub. in Society for Risk Analysis, v13 n3 p273-282 1993. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Armitage-Doll Two-Stage Model: Implications and Extension. |
| Category Codes |
57U; 68G |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/21 |
| Document Type |
NT |
| Control Number |
326626708 |
| Cataloging Source |
NTIS/MT |
| Origin |
NTIS |
| Type |
CAT |
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