OLS : Record


Main Title Armitage-Doll Two-Stage Model: Implications and Extension.
Author Chen, C. W.;
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher c1993
Year Published 1993
Report Number EPA/600/J-93/293 ;OHEA-C-462;
Stock Number PB93-222842
Subjects Carcinogens; Risk assessment; Mathematical models; Hazards; Cancer; Exposure; Reprints; MVK model; Two-stage models; ADT model
Library   Call Number Additional Info Location Date Modified
NTIS PB93-222842 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 11/22/1993
Collation 9p
Abstract The objective of the paper is twofold: (1) to provide insight on the simplified MVK model of carcinogenesis by revealing the relationship between the Armitage-Doll two-stage model (ADT model) and the simplified MVK model; and (2) to extend the ADT model to one with time-varying (piece-wise constant) parameters. It is shown that the simplified MVK model is a special case of the Armitage-Doll two-stage model , and many applications of the simplified MVK model involving intermittent exposures or exposures to different compounds in different time periods can be derived easily from the ADT model with piece-wise constant parameters. The limitations of the ADT model are discussed. (Copyright (c) 1993 Society for Risk Analysis.)
Supplementary Notes Pub. in Society for Risk Analysis, v13 n3 p273-282 1993.
NTIS Title Notes Journal article.
Title Annotations Reprint: Armitage-Doll Two-Stage Model: Implications and Extension.
Category Codes 57U; 68G
NTIS Prices PC A02/MF A01
Primary Description 600/21
Document Type NT
Control Number 326626708
Cataloging Source NTIS/MT
Origin NTIS
Type CAT