Main Title |
On the Question of the Mode of Action of the Bronchosecretolytic Agent, N-Cyclohexyl-N-Methyl-(2-Amino-3, 5-Dibromobenzyl)-Ammonium Chloride. |
Author |
Eigelsreiter, H. ;
Mair., M. ;
|
CORP Author |
National Institutes of Health, Bethesda, Md. Translation Unit.;Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section. |
Year Published |
1974 |
Report Number |
NIH-74-05C; EPA-TR-84-74; |
Stock Number |
PB-237 908-T |
Additional Subjects |
Muscle relaxants ;
Bronchi ;
Secretion ;
Drugs ;
Respiratory system ;
Pharmacology ;
West Germany ;
Translations ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-237 908-T |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
11p |
Abstract |
Although it appears to be certain that N-Cyclohexyl-N-methyl-(2-amino-3, 5-dibromobenzy)-ammonium chloride (Bisolvon) has an expectoration-promoting effect in animals, and human beings, the mechanism of action has not been thoroughly elucidated. Beside the reduction of viscosity of the bronchial secretion and a considerable increase in the granula of the secretion and of lysosomes in the caliciform cells, there also exists a dispute over an increased absorption from the bronchial tract. In the present examination an experiment was undertaken for the purposes of further clarification of the mechanism of action of Bisolvon. |