Record Display for the EPA National Library Catalog

RECORD NUMBER: 19 OF 335

Main Title Approach for Integration of Toxicological Data (Journal Version).
Author Shirazi, M. A. ; Lowrie, L. N. ;
CORP Author Corvallis Environmental Research Lab., OR. ;Northrop Services, Inc./Environmental Sciences, Corvallis, OR.
Publisher c1988
Year Published 1988
Report Number EPA/600/D-88/253;
Stock Number PB89-129472
Additional Subjects Responses ; Toxicology ; Dosage ; Sensitivity ; Tests ; Bioassay ; Comparison ; Reprints ; Chemicals ; LC 30
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Status
NTIS  PB89-129472 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 19p
Abstract
The paper presents an approach for aggregating a group of similar test data into a single mean dose-response curve with error bounds quantifying the variability of the original data. Groups of similar tests are then classified using generalized exponential dose-response functions whose constants define modes of biological response and facilitate calculation of toxicity and sensitivity. Groups of similar data and classes of different groups of tests are used to demonstrate the application and the utility of the approach. (Copyright (c) American Society for Testing and Materials, 1988.)