Record Display for the EPA National Library Catalog

RECORD NUMBER: 24 OF 79

Main Title Effect of Diphenylhydantoin on Storage of DDT in the Rat.
Author Cranmer., M. F. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1970
Stock Number PB-277 591
Additional Subjects DDT ; Pesticides ; Drugs ; Insecticides ; Storage ; Rats ; Laboratory animals ; Diets ; Enzymes ; Experimental data ; Bioassay ; Pharmacology ; Bioaccumulation ; Reprints ; DDE insecticide ; Pesticide residues ; Hydantoin/diphenyl ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB-277 591 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1p
Abstract
Dilantin is a widely used anticonvulsant drug which has been shown to stimulate liver microsomal enzymes and reduce DDT and DDE residues in man. This investigation was undertaken to study the effect of Dilantin on the storage of DDT and DDE in the rat. Dilantin was found to reduce the levels of p,p'-DDT and p,p'-DDE in the fat and to increase liver microsomal enzyme activity in all animals except those receiving 10 ppm p,p'-DDT for 14 months.