Record Display for the EPA National Library Catalog

RECORD NUMBER: 513 OF 611

Main Title Stem Cells in the Respiratory System [electronic resource] /
Type EBOOK
Author Rojas, Mauricio.
Publisher Humana Press : Imprint: Humana Press,
Year Published 2010
Call Number QH588.S83
ISBN 9781607617754
Subjects Life sciences ; Oncology ; Pneumology ; Cytology ; Stem cells
Internet Access
Description Access URL
http://dx.doi.org/10.1007/978-1-60761-775-4
Collation X, 170 p. online resource.
Notes
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Stem and Progenitor Cells of the Airway Epithelium -- Mesenchymal Stem Cells for Lung Repair and Regeneration -- The Role of Progenitor Cells in Lung Disease Prognosis -- The Role of Fibrocytes in Lung Repair and Fibrosis -- Stem Cells and Cell-Matrix Interactions in Lung -- Mobilization of Stem Cells/Progenitor Cells by Physical Activity -- Mesenchymal Stem Cells for Acute Lung Injury -- Animal Models of Lung Injury: Role for Mesenchymal Stem Cells. In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant-and recent-ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung's alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung's relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject.