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Extramural Research

Grantee Research Project Results

NCER Grantee Research Project Results

Selected Publications for Center:

University of Washington Center for Child Environmental Health Risks Research (2010)

Grant Number R834514


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Book Chapter (19)
Journal Article (76)
Reference Type Citation Progress Report Year Document Sources
Book Chapter Costa LG, Furlong CE. Paraoxonase (PON1) and detoxification of nerve agents. In: Gupta R, ed. Handbook of Toxicology of Chemical Warfare Agents. New York, NY: Elsevier, 2009, Chapter 65 (Section 8), pp. 1023-1031. R834514 (2012)
Book Chapter Costa LG, Giordano G, Guizzetti M. Predictive models for neurotoxicity assessment. In: Xu JJ, Urban L, eds. Predictive Toxicology in Drug Safety. Cambridge, UK: Cambridge University Press, 2011, Chapter 8, pp. 135-152. R834514 (2011)
Book Chapter Costa LG, Furlong CE. Paraoxonase 1: structure, function and polymorphisms. In: Satoh T, Gupta RC, eds. Anticholinesterase Pesticides: Metabolism, Neurotoxicity and Epidemiology. Hoboken, NJ: John Wiley & Sons, Inc., 2010, Chapter 7, pp. 85-95. R834514 (2011)
Book Chapter Costa LG, Giordano G, Guizzetti M. Signal transduction and neurotoxicity: what can we learn from experimental culture systems? In: Aschner M, Sunol C, Bal-Price A, eds. Cell Culture Techniques, Neuromethods, Volume 56. New York, NY: Humana Press, 2011, pp. 241-254. R834514 (2012)
Book Chapter Costa LG, Giordano G, Guizzetti M. In vitro neurotoxicology:an introduction. In:Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology:Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 1, pp. 1-9. R834514 (2012)
Book Chapter Costa LG, Giordano G, Guizzetti M. In vitro approaches to developmental neurotoxicity. In: Gupta RC, ed. Reproductive and Developmental Toxicology. New York, NY: Elsevier, 2011, Chapter 13, pp. 159-166. R834514 (2011)
Book Chapter Costa LG, Guizzetti M, Pizzurro D, Giordano G. Modulation of fibronectin expression in astrocytes affects neuritogenesis: relevance in developmental neurotoxicity. In: Beattie J, ed. Fibronectin: Current Concepts in Structure, Function and Pathology. Happauge, NY: Nova Publishers, 2012, Chapter 8. R834514 (2012)
Book Chapter Costa LG. Toxic effects of pesticides. In: Klaassen CD, ed. Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition. New York, NY: McGraw-Hill, 2013, Chapter 22, pp. 933-980. R834514 (2012)
Book Chapter Costa LG, Aschner M. Organophosphates and carbamates. In: Aminoff MJ, ed. Encyclopedia of Neurological Sciences, Second Edition. New York, NY: Elsevier, 2014, pp. 696-697. R834514 (2012)
Book Chapter Faustman EM. How might systems biology contribute to the prediction of teratogenic risk? In: Hales B, Scialli A, Tassinari M, eds. Teratology Primer-2nd Edition. Reston, VA: The Teratology Society, July 2010, Chapter 16, pp. 43-44. R832733 (Final)
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Book Chapter Furlong CE, Richter RJ, Costa LG, Jarvik GP. Paraoxonase 1 (PON1) status in risk assessment for organophosphate exposure and pharmacokinetics. In: Knaak JB, Timchalk C, Tornero-Velez R, eds. Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment, ACS Symposium Series, Volume 1099. Washington, DC: Oxford University Press, 2012, Chapter 9, pp. 133-147. R834514 (2012)
Book Chapter Giordano G, White CC, Costa LG. Assessment of glutathione homeostasis. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 14, pp. 205-214. R834514 (2012)
Book Chapter Giordano G, Hong S, Faustman E, Costa LG. Measurements of cell death in neuronal and glial cells. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 11, pp. 171-178. R834514 (2012)
Book Chapter Giordano G, Costa LG. Measurements of neuronal apoptosis. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 12, pp. 179-193. R834514 (2012)
Book Chapter Giordano G, Costa LG, Guizzetti M. Primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 2, pp.13-27. R834514 (2012)
Book Chapter Giordano G, Costa LG. Morphological assessment of neurite outgrowth in hippocampal neuron-astrocyte co-cultures. In: Costa LG, ed. Current Protocols in Toxicology. New York, NY: John Wiley & Sons, 2012, Volume 52, Unit 11:16, pp. 11.16.1–11.16.26. R834514 (2012)
Book Chapter Guizzetti M, Kavanagh TJ, Costa LG. Measurements of astrocyte proliferation. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, pp. 349-359. R834514 (2012)
Book Chapter Roque PJ, Guizzetti M, Giordano G, Costa LG. Quantification of synaptic structure formation in cocultures of astrocytes and hippocampal neurons. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology, Volume 758. New York, NY: Springer Humana, June 2011, Chapter 25, pp. 361-390. R834514 (2012)
Book Chapter Yu X, Ponce RA, Faustman EM. Metals induced disruption of ubiquitin proteasome system, activation of stress signaling and apoptosis. In: Banfalvi G, ed. Cellular Effects of Heavy Metals. Dordrecht, Netherlands: Springer, 2011, Chapter 14, pp. 291-311. R832733 (Final)
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Journal Article Armstrong J, Fenske R, Yost MG, Galvin K, Tchong-French M, Yu J. Presence of organophosphorus pesticide oxygen analogs in air samples. Atmospheric Environment 2013;66:145-150. R834514 (2012)
Journal Article Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, Gong Y, Hopewell JC, Johnson T, Kleber ME, Langaee TY, Li M, Li YR, Liu K, McDonough CW, Meijs MF, Middelberg RP, Musunuru K, Nelson CP, O'Connell JR, Padmanabhan S, Pankow JS, Pankratz N, Rafelt S, Rajagopalan R, Romaine SP, Schork NJ, Shaffer J, Shen H, Smith EN, Tischfield SE, van der Most PJ, van Vliet-Ostaptchouk JV, Verweij N, Volcik KA, Zhang L, Bailey KR, Bailey KM, Bauer F, Boer JM, Braund PS, Burt A, Burton PR, Buxbaum SG, Chen W, Cooper-Dehoff RM, Cupples LA, deJong JS, Delles C, Duggan D, Fornage M, Furlong CE, Glazer N, Gums JG, Hastie C, Holmes MV, Illig T, Kirkland SA, Kivimaki M, Klein R, Klein BE, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix AZ, Mallela L, Murugesan G, Ordovas J, Ouwehand WH, Post WS, Saxena R, Scharnagl H, Schreiner PJ, Shah T, Shields DC, Shimbo D, Srinivasan SR, Stolk RP, Swerdlow DI, Taylor HA Jr, Topol EJ, Toskala E, van Pelt JL, van Setten J, Yusuf S, Whittaker JC, Zwinderman AH; LifeLines Cohort Study, Anand SS, Balmforth AJ, Berenson GS, Bezzina CR, Boehm BO, Boerwinkle E, Casas JP, Caulfield MJ, Clarke R, Connell JM, Cruickshanks KJ, Davidson KW, Day IN, de Bakker PI, Doevendans PA, Dominiczak AF, Hall AS, Hartman CA, Hengstenberg C, Hillege HL, Hofker MH, Humphries SE, Jarvik GP, Johnson JA, Kaess BM, Kathiresan S, Koenig W, Lawlor DA, März W, Melander O, Mitchell BD, Montgomery GW, Munroe PB, Murray SS, Newhouse SJ, Onland-Moret NC, Poulter N, Psaty B, Redline S, Rich SS, Rotter JI, Schunkert H, Sever P, Shuldiner AR, Silverstein RL, Stanton A, Thorand B, Trip MD, Tsai MY, van der Harst P, van der Schoot E, van der Schouw YT, Verschuren WM, Watkins H, Wilde AA, Wolffenbuttel BH, Whitfield JB, Hovingh GK, Ballantyne CM, Wijmenga C, Reilly MP, Martin NG, Wilson JG, Rader DJ, Samani NJ, Reiner AP, Hegele RA, Kastelein JJ, Hingorani AD, Talmud PJ, Hakonarson H, Elbers CC, Keating BJ, Drenos F. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics 2012;91(5):823-838. R834514 (2012)
Journal Article Baker PE, Cole TB, Cartwright M, Suzuki SM, Thummel KE, Lin YS, Co AL, Rettie AE, Kim JH, Furlong CE. Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants. Chemico-Biological Interactions 2013;203(1):257-264. R834514 (2012)
Journal Article Balk SJ, Council on Environmental Health-Section on Dermatology. Technical report—ultraviolet radiation:a hazard to children and adolescents. Pediatrics 2011;127(3):e791-e817. R834514 (2011)
Journal Article Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, Chroni A, Yonekawa K, Stein S, Schaefer N, Mueller M, Akhmedov A, Daniil G, Manes C, Templin C, Wyss C, Maier W, Tanner FC, Matter CM, Corti R, Furlong C, Lusis AJ, von Eckardstein A, Fogelman AM, Luscher TF, Landmesser U. Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. The Journal of Clinical Investigation 2011;121(7):2693-2708. R834514 (2011)
Journal Article Buka I, Osornio-Vargas A, Karr C. Melamine food contamination: relevance to Canadian children. Paediatrics and Child Health 2009;14(4):222-224. R834514 (2012)
Journal Article Clark NA, Demers PA, Karr CJ, Koehoorn M, Lencar C, Tamburic L, Brauer M. Effect of early life exposure to air pollution on development of childhood asthma. Environmental Health Perspectives 2010;118(2):284-290. R834514 (2011)
Journal Article Cole TB, Jansen K, Park S, Li W-F, Furlong CE, Costa LG. The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. Advances in Experimental Medicine and Biology 2010;660:47-60. R831709 (2007)
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Journal Article Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG, Furlong CE. Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression. Toxicological Sciences 2011;123(1):155-169. R834514 (2011)
Journal Article Cole TB, Giordano G, Co AL, Mohar I, Kavanagh TJ, Costa LG. Behavioral characterization of GCLM-knockout mice, a model for enhanced susceptibility to oxidative stress. Journal of Toxicology 2011;2011:157687. R834514 (2011)
Journal Article Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE. Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicology and Teratology 2012;34(3):311-322. R834514 (2011)
Journal Article Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B. Organophosphate pesticide exposure among pome and non-pome farmworkers:a subgroup analysis of a community randomized trial. Journal of Occupational and Environmental Medicine 2009;51(4):500-509. R831709 (2007)
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Journal Article Coronado GD, Griffith WC, Vigoren EM, Faustman EM, Thompson B. Where's the dust? Characterizing locations of azinphos-methyl residues in house and vehicle dust among farmworkers with young children. Journal of Occupational and Environmental Hygiene 2010;7(12):663-671. R832733 (Final)
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Journal Article Coronado GD, Holte S, Vigoren E, Griffith WC, Faustman E, Thompson B. Organophosphate pesticide exposure and residential proximity to nearby fields: evidence for the drift pathway. Journal of Occupational and Environmental Medicine 2011;53(8):884-891. R832733 (Final)
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Journal Article Costa LG, Giordano G, Guizzetti M. In vitro models to study cell-cell interactions that influence developmental neurotoxicity. ALTEX 2010;27(Suppl 1):303-308. R834514 (2011)
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Journal Article Costa LG, Giordano G, Furlong CE. Pharmacological and dietary modulators of paraxonase 1 (PON1) activity and expression:the hunt goes on. Biochemical Pharmacology 2011;81(3):337-344. R834514 (2011)
Journal Article Costa LG, Giordano G, Cole TB, Marsillach J, Furlong C. Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity. Toxicology 2013;307:115-122. R834514 (2012)
Journal Article Council on Environmental Health. Chemical-management policy: prioritizing children’s health. Pediatrics 2011;127(5):983-990. R834514 (2011)
Journal Article Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP. Human PON1, a biomarker of risk of disease and exposure. Chemico-Biological Interactions 2010;187(1-3):355-361. R831709 (2007)
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Journal Article Furlong CE. Exposure to triaryl phosphates: metabolism and biomarkers of exposure. Journal of Biological Physics and Chemistry 2011;11:165-171. R834514 (2012)
Journal Article Giordano G, Guizzetti M, Dao K, Mattison HA, Costa LG. Ethanol impairs muscarinic receptor-induced neuritogenesis in rat hippocampal slices: role of astrocytes and extracellular matrix proteins. Biochemical Pharmacology 2011;82(11):1792-1799. R834514 (2012)
Journal Article Giordano G, Cole TB, Furlong CE, Costa LG. Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? Toxicology and Applied Pharmacology 2011;256(3):369-378. R834514 (2011)
Journal Article Griffith W, Curl CL, Fenske RA, Lu CA, Vigoren EM, Faustman EM. Organophosphate pesticide metabolite levels in pre-school children in an agricultural community: within-and between-child variability in a longitudinal study. Environmental Research 2011;111(6):751-756. R832733 (Final)
R834514 (2011)
Journal Article Guizzetti M, Moore NH, Giordano G, VanDeMark KL, Costa LG. Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. Glia 2010;58(12):1395-1406. R831709 (2007)
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Journal Article Guizzetti M, Moore NH, VanDeMark KL, Giordano G, Costa LG. Muscarinic receptor-activated signal transduction pathways involved in the neuritogenic effect of astrocytes in hippocampal neurons. European Journal of Pharmacology 2011;659(2-3):102-107. R834514 (2012)
Journal Article Guo Y, Lanktree MB, Taylor KC, Hakonsarson H, Lange LA, Keating BJ, IBC 50K SNP Array BMI Consortium. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Human Molecular Genetics 2013;22(1):184-201. R834514 (2012)
Journal Article Hofmann JN, Keifer MC, De Roos AJ, Fenske RA, Furlong CE, van Belle G, Checkoway H. Occupational determinants of serum cholinesterase inhibition among organophosphate-exposed agricultural pesticide handlers in Washington State. Occupational and Environmental Medicine 2009;67(6):375-386. R834514 (2012)
Journal Article Hofmann JN, Keifer MC, Checkoway H, De Roos AJ, Farin FM, Fenske RA, Richter RJ, van Belle G, Furlong CE. Biomarkers of sensitivity and exposure in Washington State pesticide handlers. Advances in Experimental Medicine and Biology 2010;660:19-27. R834514 (2011)
Journal Article Jackson JE, Yost MG, Karr CJ, Fitzpatrick C, Lamb BK, Chung S, Chen J, Avise J, Rosenblatt RA, Fenske RA. Public health impacts of climate change in Washington State: projected mortality risks due to heat events and air pollution. Climatic Change 2010;102(1-2):159-186. R834514 (2011)
Journal Article Jansen KL, Cole TB, Park SS, Furlong CE, Costa LG. Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. Toxicology and Applied Pharmacology 2009;236(2):142-153. R834514 (2012)
Journal Article Karr CJ, Rudra CB, Miller KA, Gould TR, Larson T, Sathyanarayana S, Koenig JQ. Infant exposure to fine particulate matter and traffic and risk of hospitalization for RSV bronchiolitis in a region with lower ambient air pollution. Environmental Research 2009;109(3):321-327. R834514 (2012)
Journal Article Karr CJ. Drinking water from private wells and risk to children. Pediatrics 2009;123(6):1599-1605. R834514 (2012)
Journal Article Karr CJ. Built environment: designing communities to promote active children. Pediatrics 2009;123:1591-1598. R834514 (2012)
Journal Article Karr CJ. Tobacco use: a pediatric disease. Pediatrics 2009;124(5):1474-1487. R834514 (2012)
Journal Article Karr CJ, Demers PA, Koehoorn MW, Lencar CC, Tamburic L, Brauer M. Influence of ambient air pollutant sources on clinical encounters for infant bronchiolitis. American Journal of Respiratory and Critical Care Medicine 2009;180(10):995-1001. R834514 (2012)
Journal Article Karr CJ. Adding fuel to the fire:increasing evidence for developmental toxicity of indoor solid fuel combustion. Archives of Pediatric & Adolescent Medicine 2011;165(6):565-566. R834514 (2011)
Journal Article Karr CJ. Addressing environmental contaminants in pediatric practice. Pediatrics in Review 2011;32(5):190-200. R834514 (2011)
Journal Article Karr CJ. Children's environmental health in agricultural settings. Journal of Agromedicine 2012;17(2):127-139. R834514 (2011)
Journal Article Kim DS, Burt AA, Ranchalis JE, Richter RJ, Marshall JK, Nakayama KS, Jarvik ER, Eintracht JF, Rosenthal EA, Furlong CE, Jarvik JP. Dietary cholesterol increases paraoxonase 1 enzyme activity. The Journal of Lipid Research 2012;53(11):2450-2458. R834514 (2012)
Journal Article Kim DS, Burt AA, Ranchalis JE, Richter RJ, Marshall JK, Eintracht JF, Rosenthal EA, Furlong CE, Jarvik GP. Additional common polymorphisms in the PON gene cluster predict PON1 activity but not vascular disease. Journal of Lipids 2012;2012:476316, R834514 (2012)
Journal Article Kim DS, Burt AA, Crosslin DR, Robertson PD, Ranchalis JE, Boyko EJ, Nickerson DA, Furlong CE, Jarvik GP. Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL. Journal of Lipid Research 2013;54(2):552-560. R834514 (2012)
Journal Article Kim JH, Stevens RC, MacCoss MJ, Goodlett DR, Scherl A, Richter RJ, Suzuki SM, Furlong CE. Identification and characterization of biomarkers of organophosphorus exposures in humans. Advances in Experimental Medicine and Biology 2010;660:61-71. R834514 (2011)
Journal Article Kim JH, Yeo WH, Shu Z, Soelberg SD, Inoue S, Kalyanasundaram D, Ludwig J, Furlong CE, Riley JJ, Weigel KM, Cangelosi GA, Oh K, Lee KH, Gao D, Chung JH. Immunosensor towards low-cost, rapid diagnosis of tuberculosis. Lab on a Chip 2012;12(8):1437-1440. R834514 (2012)
Journal Article Kullman SW, Hamm JT, Hinton DE. Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes). Archives of Biochemistry and Biophysics 2000;380(1):29-38. R825298 (Final)
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Journal Article Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer A, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszewski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn II GW, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ, Watkins H, Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT, Kumari M, Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height. American Journal of Human Genetics 2011;88(1):6-18. R834514 (2011)
Journal Article Liyasova M, Li B, Schopfer LM, Nachon F, Masson P, Furlong CE, Lockridge O. Exposure to tri-o-cresyl phosphate detected in jet airplane passengers. Toxicology and Applied Pharmacology 2011;256(3):337-347. R834514 (2012)
Journal Article MacIntyre EA, Karr CJ, Koehoorn M, Demers P, Tamburic L, Lencar C, Brauer M. Otitis media incidence and risk factors in a population-based birth cohort. Paediatrics and Child Health 2010;15(7):437-442. R834514 (2012)
Journal Article MacIntyre EA, Karr CJ, Koehoorn M, Demers PA, Tamburic L, Lencar C, Brauer M. Residential air pollution and otitis media during the first two years of life. Epidemiology 2011;22(1):81-89. R834514 (2011)
Journal Article Mackenzie Ross SJ, Brewin CR, Curran HV, Furlong CE, Abraham-Smith KM, Harrison V. Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides. Neurotoxicology and Teratology 2010;32(4):452-459. R834514 (2011)
Journal Article Marsillach J, Richter RJ, Kim JH, Stevens RC, MacCoss MJ, Tomazela D, Suzuki SM, Schopfer LM, Lockridge O, Furlong CE. Biomarkers of organophosphorus (OP) exposures in humans. Neurotoxicology 2011;32(5):656-660. R834514 (2011)
Journal Article Marsillach J, Hsieh EJ, Richter RJ, Maccoss MJ, Furlong CE. Proteomic analysis of adducted butyrylcholinesterase for biomonitoring organophosphorus exposures. Chemico-Biological Interactions 2013;203(1):85-90. R834514 (2012)
Journal Article Moreira EG, Yu X., Robinson JF, Griffith W, Hong SW, Beyer RP, Bammler TK, Faustman EM. Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos. Toxicology and Applied Pharmacology 2010;245(3):310-325. R831709 (2007)
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Journal Article O’Toole TE, Conklin DJ, Bhatnagar A. Environmental risk factors for heart disease. Reviews on Environmental Health 2008;23(3):167-202. EM833367 (2009)
EM833367 (Final)
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Journal Article Paulson JA, Karr CJ, Seltzer JM, Cherry DC, Sheffield PE, Cifuentes E, Buka I, Amler RW. Development of the pediatric environmental health specialty unit network in North America. American Journal of Public Health 2009;99(Suppl 3):S511-S516. R834514 (2012)
Journal Article Postma J, Karr C, Kieckhefer G. Community health workers and environmental interventions for children with asthma: a systematic review. Journal of Asthma 2009;46(6):564-576. R834514 (2012)
Journal Article Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 (PON1) status and substrate hydrolysis. Toxicology and Applied Pharmacology 2009;235(1):1-9. R831709 (2007)
R834514 (2012)
Journal Article Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 status as a risk factor for disease or exposure. Advances in Experimental Medicine and Biology 2010;660:29-35. R834514 (2011)
Journal Article Roberts JR, Karr C. Pesticide exposure in children. Pediatrics 2012;130(6):e1765-e1788. R834514 (2012)
Journal Article Roberts JR, Karr C, de Ybarrondo L, McCurdy LE, Freeland KD, Husley TC, Forman J. Improving pediatrician knowledge about environmental triggers of asthma. Clinical Pediatrics 2013;52(6):527-533. R834514 (2012)
Journal Article Robinson JF, Guerrette Z, Yu X, Hong S, Faustman EM. A systems-based approach to investigate dose-and time-dependent methylmercury-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation. Birth Defects Research. Part B: Developmental and Reproductive Toxicology 2010;89(3):188-200. R832733 (Final)
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Journal Article Robinson JF, Yu X, Hong S, Zhou C, Kim N, DeMasi D, Faustman EM. Embryonic toxicokinetic and dynamic differences underlying strain sensitivity to cadmium during neurulation. Reproductive Toxicology 2010;29(3):279-285. R831709 (2007)
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Journal Article Robinson JF, Port JA, Yu X, Faustman EM. Integrating genetic and toxicogenomic information for determining underlying susceptibility to developmental disorders. Birth Defects Research. Part A: Clinical and Molecular Teratology 2010;88(10):920-930. R832733 (Final)
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Journal Article Robinson JF, Griffith WC, Yu X, Hong S, Kim E, Faustman EM. Methylmercury induced toxicogenomic response in C57 and SWV mouse embryos undergoing neural tube closure. Reproductive Toxicology 2010;30(2):284-291. R832733 (Final)
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Journal Article Robinson JF, Yu X, Moreira EG, Hong S, Faustman EM. Arsenic- and cadmium-induced toxicogenomic response in mouse embryos undergoing neurulation. Toxicology and Applied Pharmacology 2011;250(2):117-129. R832733 (Final)
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Journal Article Sathyanarayana S, Basso O, Karr CJ, Lozano P, Alavanja M, Sandler DP, Hoppin JA. Maternal pesticide use and birth weight in the Agricultural Health Study. Journal of Agromedicine 2010;15(2):127-136. R834514 (2011)
Journal Article Sathyanarayana S, Zhou C, Rudra CB, Gould TR, Larson T, Koenig JQ, Karr CJ. Prenatal ambient air pollution exposure and small for gestational age birth in the Puget Sound air basin. Air Quality, Atmosphere & Health 2013;6(2):455-463. R834514 (2012)
Journal Article Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM; Look AHEAD Research Group; DIAGRAM consortium, Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW 2nd, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics 2012;90(3):410-425. R834514 (2012)
Journal Article Schopfer LM, Furlong CE, Lockridge O. Development of diagnostics in the search of an explanation of aerotoxic syndrome. Analytical Biochemistry 2010;404(1):64-74. R834514 (2011)
Journal Article Suzuki SM, Stevens RC, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE. Engineering human PON1 in an E. coli expression system. Advances in Experimental Medicine and Biology 2010;660:37-45. R831709 (2007)
R834514 (2011)
Journal Article Ticozzi N, LeClerc AL, Keagle PJ, Glass JD, Wills AM, van Blitterswijk M, Bosco DA, Rodriguez-Levva I, Gellera C, Ratti A, Taroni F, McKenna-Yasek D, Sapp PC, Silani V, Furlong CE, Brown Jr. RH, Landers JE. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Annals of Neurology 2010;68(1):102-107. R834514 (2011)
Journal Article Weiner MW, Meyerhoff DJ, Neylan TC, Hlavin J, Ramage ER, McCoy D, Studholme C, Cardenas V, Marmar C, Truran D, Chu PW, Kornak J, Furlong CE, McCarthy C. The relationship between Gulf War war illness, brain N-acetylaspartate, and post-traumatic stress disorder. Military Medicine 2011;176(8):896-902. R834514 (2011)
Journal Article Whitely Binder LC, Barcelos JK, Booth DB, Darzen M, Elsner MM, Fenske R, Graham TF, Hamlet AF, Hodges-Howell J, Jackson JE, Karr C, Keys PW, Littell JS, Mantua N, Marlow J, McKenzie D, Robinson-Dorn M, Rosenberg EA, Stockle CO, Vano JA. Preparing for climate change in Washington State. Climatic Change 2010;102(1-2):351-376. R834514 (2011)
Journal Article Woodruff TJ, Parker JD, Darrow LA, Slama R, Bell ML, Choi H, Glinianaia S, Hoggatt KJ, Karr CJ, Lobdell DT, Wilhelm M. Methodological issues in studies of air pollution and reproductive health. Environmental Research 2009;109(3):311-320. R833863 (2009)
R834514 (2012)
Journal Article Yu X, Robinson JF, Sidhu JS, Hong S, Faustman EM. A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and methylmercury in mouse embryonic fibroblast. Toxicological Sciences 2010;114(2):356-377. R831709 (2007)
R832733 (Final)
R834514 (2011)
Journal Article Yu X, Sidhu JS, Hong S, Robinson JF, Ponce RA, Faustman EM. Cadmium induced p53-dependent activation of stress signaling, accumulation of ubiquitinated proteins, and apoptosis in mouse embryonic fibroblast cells. Toxicological Sciences 2011;120(2):403-412. R832733 (Final)
R834514 (2011)
Journal Article Zachek C, Karr C, Sweeney C, Daniell W, Miller M. A network of Pediatric Environmental Health Specialty Units (PEHSUs): filling a critical gap in the health care system.. Medycyna Środowiskowa - Environmental Medicine 2012;15(3):9-29. R834514 (2012)

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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