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Extramural Research

Grantee Research Project Results

Grantee Research Project Results

Selected Publications for Center:

UC Davis Center for Children’s Environmental Health

Grant Number R833292


Other views: All publications Journal articles Publications submitted after final report Redisplay this page with Reference Title, Journal, and Author Columns Display this page in RIS format

Book Chapter (5)
Journal Article (100)
Reference Type Citation Progress Report Year Document Sources
Book Chapter Berman RF, Koenig CM, Hunsaker MR, Pessah IN, LaSalle JM. Neurodevelopmental toxicology and autism spectrum disorders. In: Wang C, Slikker W, eds. Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies, and Mechanisms. Hoboken, NJ: John Wiley & Sons, 2011, Chapter 21, pp. 439-476. R833292 (2009)
Book Chapter Lein PJ, Barnhart CD, Pessah IN. Acute hippocampal slice preparation and hippocampal slice cultures. In: Costa LG, Giodano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols (Methods in Molecular Biology Volume 758), New York, NY: Humana Press, 2011, Chapter 8, pp. 115-134. R833292 (2011)
Book Chapter Pessah IN, Lein PJ. Evidence for environmental susceptibility in autism. What we need to know about gene x environment interactions. In: Zimmerman AW, ed. Austim: Current Theories and Evidence. Totowa, NJ: Humana Press, 2008, Chapter 19, pp. 409-428. R833292 (2008)
Book Chapter Pessah IN. Autism spectrum disorders (introduction). In: Wang C, Slikker W, eds. Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies, and Mechanisms. Hoboken, NJ: John Wiley & Sons, 2011, Section V, pp. 435-437. R833292 (2011)
Book Chapter Stafstrom CE, Hagerman PJ, Pessah IN. Pathophysiology of epilepsy in autism spectrum disorders. In: Noebels J, Avoli M, Rogawski M, Olsen R, Delgado-Escueta A, eds. Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition. New York, NY: Oxford University Press, 2012, Chapter 71, pp. 900-914. R833292 (2011)
Journal Article Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kultz D, Chang DPY, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens:receptor-based bioassay screens. Environmental Health Perspectives 2008;116(9):1203-1210. R829388 (Final)
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Journal Article Angkustsiri K, Krakowiak P, Moghaddam B, Wardinsky T, Gardner J, Kalamkarian N, Hertz-Picciotto I, Hansen RL. Minor physical anomalies in children with autism spectrum disorders. Autism 2011;15(6):746-760. R833292 (2011)
Journal Article Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? Journal of Autism and Developmental Disorders 2008;38(1):169-175. R829388 (2006)
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Journal Article Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. Journal of Neuroimmunology 2008;204(1-2):149-153. R833292 (2009)
Journal Article Ashwood P, Schauer J, Pessah IN, Van de Water J. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. Journal of Neuroimmunology 2009;208(1-2):130-135. R833292 (2009)
Journal Article Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain, Behavior, and Immunity 2011;25(1):40-45. R833292 (2010)
Journal Article Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain, Behavior, and Immunity 2011;25(5):840-849. R833292 (2010)
Journal Article Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. Journal of Neuroimmunology 2011;232(1-2):196-199. R833292 (2011)
Journal Article Bannister RA, Pessah IN, Beam KG. The skeletal L-type Ca2+ current is a major contributor to excitation-coupled Ca2+ entry. Journal of General Physiology 2009;133(1):79-91. R833292 (2009)
Journal Article Barrientos G, Bose DD, Feng W, Padilla I, Pessah IN. The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Molecular Pharmacology 2009;76(3):560-568. R833292 (2009)
Journal Article Berman RF, Pessah IN, Mouton PR, Mav D, Harry J. Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice. Toxicological Sciences 2008;101(2):294-309. R829388 (Final)
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Journal Article Berman RF, Pessah IN, Mouton PR, Mav D, Harry GJ. Modeling neonatal thimerosal exposure in mice. Toxicological Sciences 2008;103(2):416. R829388 (Final)
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Journal Article Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: maternally derived antibodies specific for fetal brain proteins. NeuroToxicology 2008;29(2):226-231. R829388 (Final)
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Journal Article Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. Journal of Autism and Developmental Disorders 2012;42(7):1435-1445. R833292 (2011)
Journal Article Bu B, Ashwood P, Harvey D, King IB, Van de Water J, Jin L-W.
 Fatty acid compositions of red blood cell phospholipids in children with autism.
 Prostaglandins, Leukotrienes and Essential Fatty Acids 2006;74(4):215-221. R829388 (Final)
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Journal Article Buck Louis GM, Gray Jr LE, Marcus M, Ojeda SR, Pescovitz OH, Witchel SF, Sippell W, Abbott DH, Soto A, Tyl RW, Bourguignon JP, Skakkebaek NE, Swan SH, Golub MS, Wabitsch M, Toppari J, Euling SY. Environmental factors and puberty timing: expert panel research needs. Pediatrics 2008;121(Suppl 3):S192-S207. R833292 (2009)
Journal Article Burke K, Cheng Y, Li B, Petrov A, Joshi P, Berman RF, Reuhl KR, DiCicco-Bloom E. Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E. NeuroToxicology 2006;27(6):970-981. R829388 (2006)
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Journal Article Cabanlit M, Maitland D, Wilson T, Simon S, Wun T, Gershwin ME, Van de Water J. Polyurethane shape-memory polymers demonstrate functional biocompatibility in vitro. Macromolecular Bioscience 2007;7(1):48-55. R833292 (2007)
Journal Article Cabanlit M, Wills S, Goines P, Ashwood P, Van de Water J. Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder. Annals of the New York Academy of Sciences 2007;1107:92-103. R833292 (2007)
Journal Article California Dental Association Foundation, American College of Obstetricians and Gynecologists District IX. Oral health during pregnancy and early childhood: evidence-based guidelines for health professionals. Journal of the California Dental Association 2010;38(6):391-403, 405-440. R833292 (2010)
Journal Article Campbell MA, Golub MS, Iyer P, Kaufman FL, Li LH, Moran Messen F, Morgan JE, Donald JM. Reduced water intake: implications for rodent developmental and reproductive toxicity studies. Birth Defects Research Part B: Developmental and Reproductive Toxicology 2009; 86(3):157-175. R833292 (2009)
Journal Article Careaga M, Van de Water J, Ashwood P. Immune dysfunction in autism: a pathway to treatment. Neurotherapeutics 2010;7(3):283-292. R833292 (2011)
Journal Article Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB Journal 2006;20(2):329-330. R829388 (2006)
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Journal Article Croen LA, Goines P, Braunschweig D, Yolken R, Yoshida CK, Grether JK, Fireman B, Kharrazi M, Hansen RL, Van de Water J. Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) Study. Autism Research 2008;1(2):130-137. R833292 (2008)
Journal Article Croen LA, Braunschweig D, Haapanen L, Yoshida CK, Fireman B, Grether JK, Kharrazi M, Hansen RL, Ashwood P, Van de Water J. Maternal mid-pregnancy autoantibodies to fetal brain protein: the Early Markers for Autism Study. Biological Psychiatry 2008;64(7):583-588. R833292 (2008)
Journal Article Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain, Behavior, and Immunity 2009:23(1):124-133. R833292 (2009)
Journal Article Enstrom AM, Onore CE, Van de Water JA, Ashwood P. Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain, Behavior, and Immunity 2010;24(1):64-71. R833292 (2009)
Journal Article Enstrom A, Onore C, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Detection of IL-17 and IL-23 in plasma samples of children with autism. American Journal of Biochemistry and Biotechnology 2008;4(2):114-120. R829388 (2007)
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Journal Article Enstrom A, Onore C, Tarver A, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Peripheral blood leukocyte production of BDNF following mitogen stimulation in early onset and regressive autism. American Journal of Biochemistry and Biotechnology 2008;4(2):121-129. R829388 (2007)
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Journal Article Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. Increased IgG4 levels in children with autism disorder. Brain, Behavior, and Immunity 2009;23(3):389-395. R833292 (2009)
Journal Article Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium 2008;43(3):307-314. R829388 (Final)
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Journal Article Goines PE, Croen LA, Braunschweig D, Yoshida, CK, Grether J, Hansen R, Kharrazi M, Ashwood P, Van de Water J. Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: a case-control study. Molecular Autism 2011;2:13. R833292 (2011)
Journal Article Goines P, Schauer J, Heuer L, Ashwood P, Van de Water J. Beta-2-microglobulin in autism spectrum disorders. American Journal of Biochemistry and Biotechnology 2007;3(2):87-91. R829388 (Final)
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Journal Article Goines P, Van de Water J. The immune system's role in the biology of autism. Current Opinion in Neurology 2010;23(2):111-117. R833292 (2009)
Journal Article Goines P, Haapanen L, Boyce R, Duncanson P, Braunschweig D, Delwiche L, Hansen R, Hertz-Picciotto I, Ashwood P, Van de Water J. Autoantibodies to cerebellum in children with autism associate with behavior. Brain, Behavior, and Immunity 2011;25(3):514-523. R833292 (2011)
Journal Article Goth SR, Chu RA, Pessah IN. Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression. Journal of Immunological Methods 2006;308(1-2):179-191. R829388 (2006)
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Journal Article Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environmental Health Perspectives 2006;114(7):1083-1091. R829388 (2006)
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Journal Article Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR. Gene expression changes in children with autism. Genomics 2008;91(1):22-29. R829388 (Final)
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Journal Article Hansen RL, Ozonoff S, Krakowiak P, Angkustsiri K, Jones C, Deprey LJ, Le D-N, Croen LA, Hertz-Picciotto I. Regression in autism: prevalence and associated factors in the CHARGE Study. Ambulatory Pediatrics 2008;8(1):25-31. R829388 (2007)
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Journal Article Herr CE, Dostal M, Ghosh R, Ashwood P, Lipsett M, Pinkerton KE, Sram R, Hertz-Picciotto I. Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths. Environmental Health 2010;9(46). R833292 (2010)
Journal Article Herr CEW, Ghosh R, Dostal M, Skokanova V, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Yap P-S, Frost JD, Sram R, Hertz-Picciotto I. Exposure to air pollution in critical prenatal time windows and IgE levels in newborns. Pediatric Allergy and Immunology 2011;22(1 Pt 1):75-84. R833292 (2011)
Journal Article Hertz-Picciotto I, Charles MJ, James RA, Keller JA, Willman E, Teplin S. In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth. Epidemiology 2005;16(5):648-656. R829388 (2006)
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Journal Article Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, Van de Water J, Pessah IN. The CHARGE Study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environmental Health Perspectives 2006;114(7):1119-1125. R829388 (2006)
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Journal Article Hertz-Picciotto I, Baker RJ, Yap PS, Dostal M, Joad JP, Lipsett M, Greenfield T, Herr CE, Benes I, Shumway RH, Pinkerton KE, Sram R. Early childhood lower respiratory illness and air pollution. Environmental Health Perspectives 2007;115(10):1510-1518. R829388 (2007)
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Journal Article Hertz-Picciotto I, Park H-Y, Dostal M, Kocan A, Trnovec T, Sram R. Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development. Basic & Clinical Pharmacology and Toxicology 2008;102(2):146-154. R829388 (Final)
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Journal Article Hertz-Picciotto I, Jusko TA, Willman EJ, Baker RJ, Keller JA, Teplin SW, Charles MJ. A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. Environmental Health 2008;7:37. R829388 (Final)
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Journal Article Hertz-Picciotto I, Delwiche L. The rise in autism and the role of age at diagnosis. Epidemiology 2009;20(1):84-90. R833292 (2009)
Journal Article Hertz-Picciotto I, Cassady D, Lee K, Bennett DH, Ritz B, Vogt R. Study of Use of Products and Exposure-Related Behaviors (SUPERB): study design, methods, and demographic characteristics of cohorts. Environmental Health 2010;9:54. R833292 (2010)
Journal Article Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environmental Health Perspectives 2010;118(1):161-166. R833292 (2009)
Journal Article Hertz-Picciotto I, Bergman A, Fangstrom B, Rose M, Krakowiak P, Pessah I, Hansen R, Bennett DH. Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study. Environmental Health 2011;10(1):1 (11 pp.). R833292 (2011)
Journal Article Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Research 2008;1(5):275-283. R833292 (2009)
Journal Article Heuer L, Braunschweig D, Ashwood P, Van de Water J, Campbell DB. Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. Translational Psychiatry 2011;1:e48 (7 pp.). R833292 (2011)
Journal Article Howards PP, Hertz-Picciotto I. Invited commentary: disinfection by-products and pregnancy loss—lessons. American Journal of Epidemiology 2006;164(11):1052-1055. R829388 (2007)
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Journal Article Jaubert PJ, Golub MS, Lo YY, Germann SL, Dehoff MH, Worley PF, Kang SH, Schwarz MK, Seeburg PH, Berman RF. Complex, multimodal behavioral profile of the Homer1 knockout mouse. Genes, Brain and Behavior 2007;6(2):141-154. R829388 (2006)
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Journal Article Jusko TA, Koepsell TD, Baker RJ, Greenfield TA, Willman EJ, Charles MJ, Teplin SW, Checkoway H, Hertz-Picciotto I. Maternal DDT exposures in relation to fetal and 5-year growth. Epidemiology 2006;17(6):692-700. R829388 (2007)
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Journal Article Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Sonneborn D, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I. A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age. Environmental Research 2010;110(4):388-395. R833292 (2010)
Journal Article Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7646-7651. R829388 (2006)
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Journal Article Kim KH, Pessah IN. Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. NeuroToxicology 2011;32(6):981-985. R833292 (2011)
Journal Article Krakowiak P, Goodlin-Jones B, Hertz-Picciotto I, Croen LA, Hansen RL. Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study. Journal of Sleep Research 2008;17(2):197-206. R829388 (Final)
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Journal Article Magby JP, Neal AP, Atchison WD, Pessah IP, Shafer TJ. Channelopathies: summary of the hot topic keynotes session. NeuroToxicology 2011;32(5):661-665. R833292 (2011)
Journal Article Martin LA, Ashwood P, Braunschweig D, Cabanlit M, Van de Water J, Amaral DG. Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism. Brain, Behavior, and Immunity 2008;22(6):806-816. R829388 (Final)
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Journal Article Masuno MN, Pessah IN, Olmstead MM, Molinski TF. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. Journal of Medicinal Chemistry 2006;49(15):4497-4511. R829388 (2006)
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Journal Article Merin N, Young GS, Ozonoff S, Rogers SJ. Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants. Journal of Autism and Developmental Disorders 2007;37(1):108-121. R829388 (2007)
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Journal Article Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives 2009;117(12):1867-1872. R833292 (2009)
Journal Article Nadig AS, Ozonoff S, Young GS, Rozga A, Sigman M, Rogers SJ. A prospective study of response to name in infants at risk for autism. Archives of Pediatrics & Adolescent Medicine 2007;161(4):378-383. R829388 (2007)
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Journal Article Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Research 2008;1(3):169-178. R833292 (2008)
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Journal Article Onore C, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen R, Van de Water J, Ashwood P. Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders. Journal of Neuroimmunology 2009;216(1-2):126-129. R833292 (2009)
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Journal Article Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain, Behavior, and Immunity 2012;26(3):383-392. R833292 (2011)
Journal Article Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells. Journal of Pharmacology and Experimental Therapeutics 2007;323(1):381-390. R829388 (Final)
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Journal Article Ozonoff S, Young GS, Goldring S, Greiss-Hess L, Herrera AM, Steele J, Macari S, Hepburn S, Rogers SJ. Gross motor development, movement abnormalities, and early identification of autism. Journal of Autism and Developmental Disorders 2008;38(4):644-656. R829388 (2007)
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Journal Article Ozonoff S, Heung K, Byrd R, Hansen R, Hertz-Picciotto I. The onset of autism: patterns of symptom emergence in the first years of life. Autism Research 2008;1(6):320-328. R833292 (2009)
Journal Article Palkovicova L, Ursinyova M, Masanova V, Yu Z, Hertz-Picciotto I. Maternal amalgam dental fillings as the source of mercury exposure in developing fetus and newborn. Journal of Exposure Science & Environmental Epidemiology 2008;18(3):326-331. R829388 (2007)
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Journal Article Park H-Y, Hertz-Picciotto I, Sovcikova E, Kocan A, Drobna B, Trnovec T. Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study. Environmental Health 2010;9:51. R833292 (2010)
Journal Article Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R. Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins. Neurotoxicology 2010;31(4):399-402. R833292 (2009)
Journal Article Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chemical Research in Toxicology 2006;19(1):92-101. R829388 (2006)
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Journal Article Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van de Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. NeuroToxicology 2008;29(3):532-545. R829388 (Final)
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Journal Article Pessah IN, Cherednichenko G, Lein PJ. Minding the calcium store: ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacology & Therapeutics 2010;125(2):260-285. R833292 (2009)
Journal Article Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. Journal of Biological Chemistry 2007;282(12):8667-8677. R829388 (Final)
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Journal Article Rose M, Bennett DH, Bergman A, Fangstrom B, Pessah IN, Hertz-Picciotto I. PBDEs in 2-5 year-old children from California and associations with diet and indoor environment. Environmental Science & Technology 2010;44(7):2648-2653. R833292 (2009)
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Journal Article Rossi CC, Van de Water J, Rogers SJ, Amaral DG. Detection of plasma autoantibodies to brain tissue in young children with and without autism spectrum disorders. Brain, Behavior, and Immunity 2011;25(6):1123-1135. R833292 (2011)
Journal Article Samso M, Feng W, Pessah IN, Allen PD. Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biology 2009;7(4):e1000085 (0980-0995). R833292 (2009)
Journal Article Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, Tassone F, Hertz-Picciotto I. Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism. Epidemiology 2011;22(4):476-485. R833292 (2011)
Journal Article Schmidt RJ, Tancredi DJ, Ozonoff S, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tassone F, Hertz-Picciotto I. Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. American Journal of Clinical Nutrition 2012;96(1):80-89. R833292 (2009)
Journal Article Shelton JF, Tancredi DJ, Hertz-Picciotto I. Independent and dependent contributions of advanced maternal and paternal ages to autism risk. Autism Research 2010;3(1):30-39. R833292 (2009)
Journal Article Sonneborn D, Park H-Y, Babinska K, Palkovicova L, Trnovec T, Kocan A, Nguyen DV, Hertz-Picciotto I. Serum PCB concentrations in relation to locally produced food items in eastern Slovakia. Journal of Exposure Science & Environmental Epidemiology 2008;18(6):581-587. R833292 (2009)
Journal Article Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotoxicity Research 2011;19(1):31-48. R833292 (2009)
R833292 (2010)
Journal Article Ta TA, Pessah IN. Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). NeuroToxicology 2007;28(4):770-779. R829388 (2006)
R829388 (Final)
R833292 (2007)
R833292 (2008)
R833292 (2009)
Journal Article Ta TA, Koenig CM, Golub MS, Pessah IN, Qi L, Aronov PA, Berman RF. Bioaccumulation and behavioral effects of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice. Neurotoxicology and Teratology 2011;33(3):393-404. R833292 (2011)
Journal Article Tassone F, Qi L, Zhang W, Hansen RL, Pessah IN, Hertz-Picciotto I. MAOA, DΒH and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism Research 2011;4(4):250-261. R833292 (2011)
Journal Article Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotoxicity Research 2011;19(1):1-13. R833292 (2009)
Journal Article Van Meter KC, Christiansen LE, Delwiche, LD, Azari R, Carpenter TE, Hertz-Picciotto I. Geographic distribution of autism in California: a retrospective birth cohort analysis. Autism Research 2010;3(1):19-29. R833292 (2009)
Journal Article Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R. Residential proximity to freeways and autism in the CHARGE Study. Environmental Health Perspectives 2011;119(6):873-877. R833292 (2011)
Journal Article Wiest MM, German JB, Harvey DJ, Watkins SM, Hertz-Picciotto I. Plasma fatty acid profiles in autism: a case-control study. Prostaglandins, Leukotrienes, and Essential Fatty Acids 2009;80(4):221-227. R833292 (2009)
Journal Article Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J. Autoantibodies in autism spectrum disorders (ASD). Annals of the New York Academy of Sciences 2007;1107:79-91. R829388 (Final)
R833292 (2007)
Journal Article Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water J. Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain, Behavior, and Immunity 2009;23(1):64-74. R833292 (2008)
Journal Article Wills S, Rossi CC, Bennett J, Martinez-Cerdeno V, Ashwood P, Amaral DG, Van de Water J. Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism. Molecular Autism 2011;2:5 (15 pp.). R833292 (2011)
Journal Article Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology 2006;105(6):1164-1175. R829388 (Final)
R833292 (2007)
Journal Article Yang T, Allen PD, Pessah IN, Lopez JR. Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. 
Journal of Biological Chemistry 2007;282(52):37471-37478. R829388 (Final)
R833292 (2007)
Journal Article Zerbo O, Iosif A-M, Delwiche L, Walker C, Hertz-Picciotto I. Month of conception and risk of autism. Epidemiology 2011;22(4):469-475. R833292 (2011)
Journal Article Zhang X, Lv CC, Tian J, Miao RJ, Xi W, Hertz-Picciotto I, Qi L. Prenatal and perinatal risk factors for autism in China. Journal of Autism and Developmental Disorders 2010;40(11):1311-1321. R833292 (2009)

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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