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Extramural Research

Grantee Research Project Results

NCER Grantee Research Project Results

Publications for Center:

San Joaquin Valley Aerosol Health Effects Research Center (SAHERC)

Grant Number R832414


Other views: Selected publication types Journal articles Publications submitted after final report Redisplay this page with Reference Title, Journal, and Author Columns Display this page in RIS format

Abstract (23)
Book Chapter (5)
Journal Article (47)
Meeting (1)
Presentation (33)
Report (1)
Reference Type Citation Progress Report Year Document Sources
Abstract Anderson DS, Chan JKW, Fanucchi MV, Van Winkle LS. Differential effect of low and high organic carbon content particulate matter in postnatal and adult rat airways. The Toxicologist 2010;114(S1):A1518. R832414 (Final)
R832414C001 (2010)
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Abstract Aung HH, Lame MW, He G, Denison MS, Wilson DW, Rutledge JC. Induction of phase I xenobiotic metabolism and pro-inflammatory gene expression in vascular endothelial cell by concentrated ambient particulate matter. American Journal of Respiratory and Critical Care Medicine 2010;181:A6784. R832414 (2010)
Abstract Buckpitt A, Pham N, Krawiec D, Morin D, Jewell W, Van Winkle L. Development of adducted peptide biomarkers to address the consequences of human exposure to rodent pulmonary toxicants. The Toxicologist 2011;120(S-2):190 (abstract A888). R832414C001 (Final)
Abstract Carosino CM, Harkema JR, Pinkerton KE. Exposure to ultrafine particles during allergic sensitization yields an altered lung epithelial structure. The Toxicologist 2009;108(1):317 (Abstract No. 1531). R832414 (2010)
R832414C003 (2009)
R832414C003 (2010)
Abstract Fanucchi MV, Davison L, DeLong B, Plopper CG, Kennedy IM, Buckpitt AR. Site-specific definition of acute airway epithelial injury following a single exposure to 1-nitronapthalene-coated carbon black particles. The Toxiocologist 2006;90(1):A1026. R832414C001 (2006)
not available
Abstract Fanucchi MV, Kumfer BM, Wallis ED, Kennedy IM. Acute airway epithelial injury from three different carbon particles with and without adsorbed 1-nitronapthalene. American Journal of Respiratory and Critical Care Medicine 2008;177 (abstract A425). R832414C001 (Final)
not available
Abstract Hopkins LE, Pinkerton KE. Rapid uptake of inhaled solid phase ultrafine particles into the olfactory bulbs of mice. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A5246. R832414 (2010)
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Abstract Krawiec D, Morin D, Van Winkle L, Buckpitt A. A means to study critical adduct protein targets: comparison of toxic naphthalene and non-toxic diethyl maleate shows equivalent in vivo covalent binding and glutathione depletion in airway epithelium. The Toxicologist 2011;120(S-2):392 (abstract A1832). R832414C001 (Final)
Abstract Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Effects of post-natal ozone or particle exposure on the structural and functional differences in rat lungs. American Journal of Respiratory and Critical Care Medicine 2009;179:319 (abstract A2579). R832414C001 (2009)
R832414C001 (Final)
Abstract Lee D, Schelegle E, Wallis C, Fanucchi M, Van Winkle L, Plopper C, Wexler A. Structural and functional differences in rat lungs due to post-natal ozone or particle exposure. The Toxicologist 2009;108(1):350 (abstract PS1687). R832414C001 (2009)
R832414C001 (Final)
Abstract Murphy SR, Chan JK, Edwards PC, Van Winkle LS. Application of in vitro methods for studying oxidant stress in lung epithelium of multiple species. Federation of American Societies for Experimental Biology 2010;24(Suppl):1001.19. R832414 (Final)
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R832414C001 (Final)
Abstract Plummer LE, Ham W, Kleeman MJ, Recendez JJ, Pinkerton KE. Murine pulmonary response following exposure to particulate matter of the California San Joaquin Valley. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A3176. R832414 (2010)
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R832414C003 (2010)
Abstract Plummer LE, Carosino CM, Wegesser TC, Last JA, Pinkerton KE. Species sensitivity to instillation-induced particle toxicity:a bioassay of particle dosimetry testing. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A1630. R832414 (2010)
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Abstract Sutherland KM, Edwards PC, Van Winkle LS. Mechanisms of pulmonary tolerance in female mice to the cytotoxicant naphthalene. The FASEB Journal 2008;22(Suppl):918.4. R832414C001 (Final)
Abstract Van Winkle LS, Edwards PC, Mathison JA, Sutherland KM, Chan JK, Mitchell VL, Anderson DS. Effect of inhaled soot on neonatal and adult rats. Molecular Biology of the Cell 2008;19(Suppl):164 (abstract 568/B520). R832414C001 (2009)
R832414C001 (Final)
Abstract Van Winkle LS, Anderson DS, Edwards P, Chan J, Mathison J, Mitchell V. Immune responses in neonatal and adult rats exposed to soot. The Toxicologist 2009;108(1):433 (abstract PS2085). R832414C001 (2009)
R832414C001 (Final)
Abstract Van Winkle LS, Edwards PC, Chan JK, Sutherland KM, Anderson DM, Krawiecz D, Buckpitt AR. Microsomal epoxide hydrolase and airway sensitivity to the air pollutant naphthalene. American Journal of Respiratory and Critical Care Medicine 2009;179:F44 (abstract A3178). R832414C001 (2009)
R832414C001 (Final)
Abstract Van Winkle LS, Sutherland K, Morin D, Edwards P, Buckpitt A. Sex differences in metabolism and toxicity in the lung. The Toxicologist 2011;120(Suppl 2):190 (abstract A887). R832414C001 (Final)
Abstract Van Winkle LS, Chan JK, Anderson DS, Fanucchi MV. Differential effect of low and high organic carbon content particulate matter in postnatal and adult rat airways. The Toxicologist 2010;114(1):322 (abstract A1518). R832414C001 (Final)
Abstract Van Winkle LS, Ding X. Metabolic basis of respiratory tract chemical toxicity. The Toxicologist 2011;120(Suppl 2):189 (abstract A884). R832414C001 (Final)
Abstract Van Winkle LS, Harkema JR. Oxidant air pollution and childhood asthma. The Toxicologist 2008;102(1):117 (abstract A568). R832414C001 (Final)
Abstract Van Winkle LS, Murphy SR, Edwards PC, Walby WF, Hyde DM, Schelegle ES. Effects of postnatal exposure history on airways: use of airway explant cultures to evaluate responses to acute oxidant stress. American Journal of Respiratory and Critical Care Medicine 2009;179:D47 (abstract A4976). R832414C001 (2009)
R832414C001 (Final)
Abstract Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman MW, Norris J, Tablin F. Platelet and systemic cytokine activation in mice exposed to concentrated ambient particulate matter. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A3146. R832414 (2010)
R832414C003 (2009)
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Book Chapter Madl AK, Carosino CE, Pinkerton KE. Airborne particles and structural remodeling of the lungs. In: Gehr P, Muhlfeld C, Rothen-Rutishauser B, Blank F, eds. Particle-Lung Interactions, Second Edition. New York, NY: Informa Healthcare USA, Inc., 2009, Chapter 10, pp.167-193. R832414 (2010)
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Book Chapter Madl AK, Carosino C, Pinkerton KE. Particle toxicities. In: McQueen CA, ed. Comprehensive Toxicology, Second Edition. New York, NY :Elsevier, 2010, Chapter 8, pp. 421-451. R832414 (2010)
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Book Chapter Plummer LE, Pinkerton KE, Madl AK, Wilson DW. Effects of nanoparticles on the pulmonary vasulature. In: Cassee FR, Mills NL, Newby D, eds. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles. Hoboken, NJ: John Wiley & Sons, Inc., 2011, Chapter 17, pp. 317-350. R832414 (2010)
R832414C003 (Final)
Book Chapter Van Winkle LS, Smiley-Jewell S, Pinkerton KE. Tracheobronchial airways. In:McQueen CA, ed. Comprehensive Toxicology (Second Edition). Amsterdam, The Netherlands: Elsevier Ltd., 2010, Volume 8, pp. 35-58. R832414 (Final)
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R832414C001 (Final)
Book Chapter Van Winkle LS. Cell damage and cell renewal in the lung. In: McQueen CA, ed. Comprehensive Toxicology (Second Edition). Amsterdam, The Netherlands: Elsevier Ltd., 2010, Volume 8, pp. 223-242. R832414 (Final)
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R832414C001 (Final)
Journal Article Aung HH, Lame MW, Gohil K, He G, Denison MS, Rutledge JC, Wilson DW. Comparative gene responses to collected ambient particles in vitro: endothelial responses. Physiological Genomics 2011;43(15):917-929. R832414 (Final)
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Journal Article Bein KJ, Zhao Y, Wexler AS. Conditional sampling for source-oriented toxicological studies using a single particle mass spectrometer. Environmental Science & Technology 2009;43(24):9445-9452. R832414C005 (Final)
Journal Article Chan JKW, Fanucchi MV, Anderson DS, Abid AD, Wallis CD, Dickinson DA, Kumfer BM, Kennedy IM, Wexler AS, Van Winkle LS. Susceptibility to inhaled flame-generated ultrafine soot in neonatal and adult rat lungs. Toxicological Sciences 2011;124(2):472-486. R832414C001 (Final)
Journal Article Day KC, Plopper CG, Fanucchi MV. Age-specific pulmonary cytochrome P-450 3A1 expression in postnatal and adult rats. American Journal of Physiology-Lung Cellular and Molecular Physiology 2006;291(1):L75-L83. R832414 (2009)
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Journal Article den Hartigh LJ, Lame MW, Ham W, Kleeman MJ, Tablin F, Wilson DW. Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species.Toxicology In Vitro 2010;24(7):1993-2002. R832414 (2010)
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Journal Article Donaldson K, Borm PJA, Oberdorster G, Pinkerton KE, Stone V, Tran CL. Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles:the key role of the proximal alveolar region. Inhalation Toxicology 2008;20(1):53-62. R829215 (Final)
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Journal Article Greeley MA, Van Winkle LS, Edwards PC, Plopper CG. Airway trefoil factor expression during naphthalene injury and repair. Toxicological Sciences 2010;113(2):453-467. R832414 (Final)
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Journal Article Ham WA, Herner JD, Green PG, Kleeman MJ. Size distribution of health-relevant trace elements in airborne particulate matter during a severe winter stagnation event: implications for epidemiology and inhalation exposure studies. Aerosol Science and Technology 2010;44(9):753-765. R832414 (2010)
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Journal Article Kennedy IM. The health effects of combustion-generated aerosols. Proceedings of the Combustion Institute 2007;31(2):2757-2770. R832414 (2009)
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Journal Article Kleeman MJ, Riddle SG, Jakober CA. Size distribution of particle-phase molecular markers during a severe winter pollution episode. Environmental Science & Technology 2008;42(17):6469-6475. R832414 (2009)
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Journal Article Kleeman MJ, Riddle SG, Robert MA, Jakober CA, Fine PM, Hays MD, Schauer JJ, Hannigan MP. Source apportionment of fine (PM1.8) and ultrafine (PM0.1) airborne particulate matter during a severe winter pollution episode. Environmental Science & Technology 2009;43(2):272-279. R832414 (2010)
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Journal Article Lee DY, Wexler AS, Fanucchi MV, Plopper CG. Expiration rate drives human airway design. Journal of Theoretical Biology 2008;253(2):381-387. R832414 (2009)
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Journal Article Lee DY, Wallis C, Wexler AS, Schelegle ES, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer B, Kennedy IM, Chan JKW. Small particles disrupt postnatal airway development. Journal of Applied Physiology 2010;109(4):1115-1124. R832414 (Final)
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Journal Article Lee D, Park SS, Ban-Weiss GA, Fanucchi MV, Plopper CG, Wexler AS. Bifurcation model for characterization of pulmonary architecture. Anatomical Record 2008;291(4):379-389. R832414 (2009)
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Journal Article Lee D, Fanucchi MV, Plopper CG, Fung J, Wexler AS. Pulmonary architecture in the conducting regions of six rats. Anatomical Record 2008;291(8):916-926. R832414 (2009)
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Journal Article Lee D, Wallis CD, Van Winkle LS, Wexler AS. Disruption of tracheobronchial airway growth following postnatal exposure to ozone and ultrafine particles. Inhalation Toxicology 2011;23(9):520-531. R832414C005 (Final)
Journal Article Lee D, Wexler AS. Simulated annealing implementation with shorter Markov chain length to reduce computational burden and its application to the analysis of pulmonary airway architecture. Computers in Biology and Medicine 2011;41(8):707-715. R832414C005 (Final)
Journal Article Lee D, Willits N, Wexler AS. Detecting alterations in pulmonary airway development with airway-by-airway comparison. Annals of Biomedical Engineering 2011;39(6):1805-1814. R832414C005 (Final)
Journal Article Lee D, Srirama PK, Wallis C, Wexler AS. Postnatal growth of tracheobronchial airways of Sprague-Dawley rats. Journal of Anatomy 2011;218(6):717-725. R832414C005 (Final)
Journal Article Lee D, Wexler AS. Particle deposition in juvenile rat lungs: a model study. Journal of Aerosol Science 2011;42(9):567-579. R832414C005 (Final)
Journal Article Madl AK, Pinkerton KE. Health effects of inhaled engineered and incidental nanoparticles. Critical Reviews in Toxicology 2009;39(8):629-658. R829215 (Final)
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Journal Article Madl AK, Teague SV, Qu Y, Masiel D, Evans JE, Guo T, Pinkerton KE. Aerosolization system for experimental inhalation studies of carbon-based nanomaterials. Aerosol Science and Technology 2012;46:(1):94-107. R832414C003 (Final)
Journal Article Nakayama Wong LS, Lame MW, Jones AD, Wilson DW. Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole. Chemical Research in Toxicology 2010;23(9):1504-1513. R832414 (2010)
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Journal Article Nakayama Wong LS, Aung HH, Lame MW, Wegesser TC, Wilson DW. Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells. Toxicology In Vitro 2011;25(8):1895-1905. R832414 (Final)
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Journal Article Ngo MA, Pinkerton KE, Freeland S, Geller M, Ham W, Cliff S, Hopkins LE, Kleeman MJ, Kodavanti UP, Meharg E, Plummer L, Recendez JJ, Schenker MB, Sioutas C, Smiley-Jewell S, Haas C, Gutstein J, Wexler AS. Airborne particles in the San Joaquin Valley may affect human health. California Agriculture 2010;64(1):12-16. R832413 (Final)
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Journal Article Palko HA, Fung JY, Louie AY. Positron emission tomography: a novel technique for investigating the biodistribution and transport of nanoparticles. Inhalation Toxicology 2010;22(8):657-688. R832414 (Final)
R832414C004 (Final)
Journal Article Pham H, Bonham AC, Pinkerton KE, Chen CY. Central neuroplasticity and decreased heart rate variability after particulate matter exposure in mice. Environmental Health Perspectives 2009;117(9):1448-1453. R831918 (Final)
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Journal Article Pinkerton KE, Joad JP. Influence of air pollution on respiratory health during perinatal development. Clinical and Experimental Pharmacology and Physiology 2006;33(3):269-272. R829215 (Final)
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Journal Article Plummer LE, Ham W, Kleeman MJ, Wexler A, Pinkerton KE. Influence of season and location on pulmonary response to California's San Joaquin Valley airborne particulate matter. Journal of Toxicology and Environmental Health 2012;75(5):253-271. R832414C003 (Final)
Journal Article Riddle SG, Robert MA, Jakober CA, Hannigan MP, Kleeman MJ. Size-resolved source apportionment of airborne particle mass in a roadside environment. Environmental Science & Technology 2008;42(17):6580-6586. R832414 (2009)
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Journal Article Ruehl CR, Ham WA, Kleeman MJ. Temperature-induced volatility of molecular markers in ambient airborne particulate matter. Atmospheric Chemistry and Physics 2011;11(1):67-76. R832414 (2010)
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Journal Article Schenker MB, Pinkerton KE, Mitchell D, Vallyathan V, Elvine-Kreis B, Green FHY. Pneumoconiosis from agricultural dust exposure among young California farmworkers. Environmental Health Perspectives 2009;117(6):988-994. R832414 (2010)
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Journal Article Sekizawa S-i, Joad JP, Pinkerton KE, Bonham AC. Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates. Toxicology and Applied Pharmacology 2010;242(2):199-208. R832414 (2010)
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Journal Article Shen H, Barakat AI, Anastasio C. Generation of hydrogen peroxide from San Joaquin Valley particles in a cell-free solution. Atmospheric Chemistry and Physics 2011;11(2):753-765. R832414 (2010)
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Journal Article Shen H, Anastasio C. Formation of hydroxyl radical from San Joaquin Valley particles extracted in a cell-free surrogate lung fluid. Atmospheric Chemistry and Physics 2011;11(18):9671-9682. R832414 (Final)
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Journal Article Shen H, Anastasio C. A comparison of hydroxyl radical and hydrogen peroxide generation in ambient particle extracts and laboratory metal solutions. Atmospheric Environment 2012;46:665-668. R832414 (Final)
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Journal Article Smith KR, Veranth JM, Kodavanti UP, Aust AE, Pinkerton KE. Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. Toxicological Sciences 2006;93(2):390-399. R829215 (Final)
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Journal Article Srirama PK, Wallis CD, Lee D, Wexler AS. Imaging extra-thoracic airways and deposited particles in laboratory animals. Journal of Aerosol Science 2012;45:40-49. R832414C005 (Final)
Journal Article Sutherland KM, Combs TJ, Edwards PC, Van Winkle LS. Site-specific differences in gene expression of secreted proteins in the mouse lung: comparison of methods to show differences by location. Journal of Histochemistry and Cytochemistry 2010;58(12):1107-1119. R832414 (Final)
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Journal Article Sutherland KM, Edwards PC, Combs TJ, Van Winkle LS. Sex differences in the development of airway epithelial tolerance to naphthalene. American Journal of Physiology-Lung Cellular and Molecular Physiology 2012;302(1):L68-L81. R832414C001 (Final)
Journal Article Tablin F, den Hartigh LJ, Aung HH, Lame MW, Kleeman MJ, Ham W, Norris JW, Pombo M, Wilson DW. Seasonal influences on CAPs exposures: differential responses in platelet activation, serum cytokines and xenobiotic gene expression. Inhalation Toxicology 2012;24(8):506-517. R832414 (Final)
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Journal Article Tebockhorst S, Lee D, Wexler AS, Oldham MJ. Interaction of epithelium with mesenchyme affects global features of lung architecture: a computer model of development. Journal of Applied Physiology 2007;102(1):294-305. R832414 (2009)
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Journal Article Van Winkle LS, Chan JK, Anderson DS, Kumfer BM, Kennedy IM, Wexler AS, Wallis C, Abid AD, Sutherland KM, Fanucchi MV. Age specific responses to acute inhalation of diffusion flame soot particles: cellular injury and the airway antioxidant response. Inhalation Toxicology 2010;22(Suppl 2):70-83. R832414 (Final)
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Journal Article Wegesser TC, Pinkerton KE, Last JA. California wildfires of 2008: coarse and fine particulate matter toxicity. Environmental Health Perspectives 2009;117(6):893-897. R832414 (2010)
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Journal Article Wexler AS, Johnston MV. What have we learned from highly time-resolved measurements during EPA's Supersites Program and related studies? Journal of the Air & Waste Management Association 2008;58(2):303-319. R832414C005 (Final)
Journal Article Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F. Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation. Inhalation Toxicology 2010;22(4):267-276. R832414 (2010)
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Journal Article Zhong C-Y, Zhou Y-M, Smith KR, Kennedy IM, Chen C-Y, Aust AE, Pinkerton KE. Oxidative injury in the lungs of neonatal rats following short-term exposure to ultrafine iron and soot particles. Journal of Toxicology and Environmental Health, Part A: Current Issues 2010;73(12):837-847. R832414 (2010)
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Meeting Wexler AS. Atmospheric chemical mechanisms. Organized Biennial Meeting at UC Davis of about 100 scientists and engineers worldwide who work on developing mathematical models of atmospheric photochemistry, December 10-12, 2008. R832414 (2010)
Presentation Anderson DS, Chan JKW, Tablin F, Fanucchi MV, Van Winkle LS. Comparative pattern of immune responses in lung and peripheral blood following Inhalation of two different particle types. Presented at the 2010 American Association for Aerosol Research (AAAR) Air Pollution and Health Specialty Conference, Bridging the Gap From Sources to Health Outcomes, San Diego, CA, March 22-26, 2010. R832414 (Final)
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Presentation Anderson DS, Chan JKW, Tablin F, Van Winkle LS. Temporal pattern in neonate and adult rats of inflammatory responses in lung and peripheral blood following inhalation of flame generated particulate matter. Presented at the Northern California chapter of the Society of Environmental Toxicology and Chemistry Annual Meeting, California State University, Sacramento, CA, May 4-5, 2011 (abstract A13, p24). R832414C001 (Final)
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Presentation Aung HH, Lame MW, Gohill K, Rutledge JC, Wilson DW. Particulate matter-induced expression of CYP1A1 gene through the AhR pathway in human aortic endothelial cells. Presented at the American Thoracic Society Annual International Conference, Toronto, Ontario, Canada, May 16-21, 2008. R832414 (Final)
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Presentation Aung HH, Lame MW, He G, Denison M, Rutledge JC, Wilson DW. Induction of phase I xenobiotic metabolism and pro-inflammatory gene expression in vascular endothelial cell by concentrated ambient particulate matter. Presented at the American Thoracic Society Annual International Conference, New Orleans, LA, May 14-19, 2010. R832414 (2010)
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Presentation Blum A, Lame M, Tablin F, Wilson DW. In vitro effects of particulate matter on human endothelial adhesion molecule expression. Presented at the Merck Meriel Summer Scholars Annual Conference, 2008. R832414C002 (2008)
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Presentation Buckpitt AR. Biomarkers of naphthalene toxicity. Presented at the 2009 Naphthalene Research Meeting of the Naphthalene Science Team, Davis, CA, June 2009. R832414C001 (2009)
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Presentation Chan J, Anderson D, Wallis C, Wexler A, Van Winkle LS. Combustion derived ultrafine particles differentially alter metabolic and antioxidant responses in neonatal and adult rats. Presented at the Northern California Chapter of the Society of Environmental Toxicology and Chemistry Annual Meeting, California State University, Sacramento, CA, May 4-5, 2011 (abstract A10, p23). R832414C001 (Final)
Presentation Chen CY, Pinkerton KE, Bonham AC. Time dependent decrease in heart rate variability to particulate matter exposure in mice. Presented at the Annual Meeting for Experimental Biology, Washington, DC, May 2007. R832414C003 (2007)
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Presentation Feliz AM, Lame MW, Kumfer B, Kennedy I, Wilson DW. Interaction of ultra fine particles and transcytosis in human aortic endothelial cells. Presented at the American Thoracic Society Annual International Conference, San Francisco, CA, May 18-23, 2007. R832414 (Final)
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Presentation Ham WA, Ruehl CR, Kleeman MJ. Seasonal variation of airborne particle deposition efficiency in the human respiratory system. Presented at the American Association for Aerosol Research (AAAR) 29th Annual Conference, Portland, OR, October 25-29, 2010. R832414 (2010)
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Presentation Lee DY, Wexler AS, Plopper C, Yang K, Miller DF, Boone JM. Characterization of lung airway architecture using a flexible bifurcation model and simulated annealing. Presented at the International Conference of the American Thoracic Society, San Diego, CA, May 19-24, 2006. R832414C005 (2006)
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Presentation Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Effects of post-natal ozone or particle exposure on the structural and functional differences in rat lungs. Presented at the International Conference of the American Thoracic Society, San Diego, CA, May 15-20, 2009. R832414C005 (2009)
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Presentation Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Structural and functional differences in rat lungs due to post-natal ozone or particle exposure. Presented at the Society of Toxicology 48th Annual Meeting & ToxExpo, Baltimore, MD, March 15-19, 2009. R832414C005 (2009)
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Presentation Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Structural and functional changes in rat lungs due to post-natal exposure to ozone with and without particles. Presented at the 2010 American Association for Aerosol Research (AAAR) Air Pollution and Health Specialty Conference, Bridging the Gap From Sources to Health Outcomes, San Diego, CA, March 22-26, 2010. R832414 (2010)
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Presentation Lee D, Srirama PK, Wallis CD, Wexler AS. Airway-by-airway identification of aerosol deposition in the laboratory animal lung. Presented at the American Association for Aerosol Research (AAAR) 30th Annual Conference, Orlando, FL, October 3-7, 2011. R832414C005 (Final)
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Presentation Lee D, Wallis C, Wexler AS. Detecting disruption in airway development due to PM exposure by comparing pulmonary airway trees. Presented at the International Conference of the American Thoracic Society, Denver, CO, May 13-18, 2011. R832414C005 (Final)
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Presentation Lee D, Wexler AS, Fanucchi MV, Plopper CG. Optimal structure of human airway architecture. Presented at the Biomedical Engineering Society Annual Fall Meeting, Los Angeles, CA, September 26-29, 2007. R832414C005 (Final)
not available
Presentation Lewis K, Nakayama Wong LS, Lame M, Wilson DW. Endothelial cell responses to environmental particulate matter. Presented at the 2008 Merck-Merial NIH Veterinary Scholars Symposium, East Lansing, MI, July 31-August 3, 2008. R832414 (Final)
R832414C002 (2008)
R832414C002 (2009)
R832414C002 (Final)
not available
Presentation Nakayama Wong LS, Lame MW, Jones AD, Wilson DW. Intracellular oxidation and the translocation of Nrf2 in human pulmonary artery endothelial cells exposed to monocrotaline pyrrole, 1,4-naphthoquinone, and naphthoquinone adducted galectin-1. Presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2007. R832414 (Final)
R832414C002 (Final)
not available
Presentation Srirama PK, Wallis CD, Lee D, Wexler AS. Imaging particle and drug deposition in airways of laboratory animals. Poster presented at Respiratory Drug Delivery (RDD) Europe, Berlin, Germany, May 3-6, 2011. R832414C005 (Final)
not available
Presentation Van Winkle LS. Naphthalene toxicity and metabolism in the mEH knockout mouse (B6;129-Ephx1). Lead roundtable discussion of Research Directions for Naphthalene. Presented at the 2008 Naphthalene Research Meeting, Storrs, CT, June 2008 (invited talk). R832414C001 (2008)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Oxidant air pollution and childhood asthma. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008 (symposium chair and organizer). R832414C001 (2008)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Comparative biology of the lung (continuing education course) and metabolism and enzymatic balance in the respiratory tract (presentation). Presented at the Society of Toxicology 49th Annual Meeting & ToxExpo, Salt Lake City, UT, March 7-11, 2010. R832414 (Final)
R832414C001 (2010)
R832414C001 (Final)
not available
Presentation Van Winkle LS, Chan JKW, Anderson DS, Fanucchi MV. Particle inhalation in postnatal and adult rats: expression of toxicity and oxidative stress associated genes in airways. Presented at the 2010 American Association for Aerosol Research (AAAR) Air Pollution and Health Specialty Conference, Bridging the Gap From Sources to Health Outcomes, San Diego, CA, March 22-26, 2010. R832414 (Final)
R832414C001 (2010)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Site specific methods in the lung to improve toxicity testing. Presented at the Hamner Institute, Research Triangle Park, NC, June 2011. R832414C001 (Final)
not available
Presentation Van Winkle LS. Sex differences in metabolism and toxicity in the lung. Presented at the Society of Toxicology 50th Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. R832414C001 (Final)
not available
Presentation Van Winkle LS. Ozone and the lung: biological effects during development. Presented at the Sierra Ozone Summit, Holiday Inn Express, Grass Valley, CA, June 4, 2008 (invited talk). R832414C001 (2008)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Pulmonary toxicity of naphthalene: lessons from animal studies. Presented at the University of Arizona, Tuscon, AZ, January 2009 (invited). R832414C001 (2009)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Research directions for naphthalene: are we ready to leave rodents behind? Presented at the 2009 Naphthalene Research Meeting of the Naphthalene Science Team, Davis, CA, June 2009 (lead and moderated roundtable discussion). R832414C001 (2009)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Genetic and environmental influences on injury and repair in the conducting airway. Presented at the Johns Hopkins School of Public Health, Baltimore, MD, March 2009 (invited). R832414C001 (2009)
R832414C001 (Final)
not available
Presentation Van Winkle LS. Factors influencing respiratory tract chemical toxicity. Presented at the Society of Toxicology 50th Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. R832414C001 (Final)
not available
Presentation Wexler AS. Revolution in aviation. Presented at the Annual Meeting of Stakeholders from Local and Federal Government, Airlines, Airplane and Jet Engine Manufacturers and Environmental and Community Groups to Discuss the Latest Developments in Noise and Air Pollution Emissions from Airports, March 1-4, 2009. R832414 (2010)
not available
Presentation Wexler AS. Green acres, blue skies II. Presented at the Annual Meeting of Agricultural and Environmental Interests in the Western US, 2010. R832414 (2010)
not available
Report Pinkerton KE, Zhou Y, Zhong C, Smith KR, Teague SV, Kennedy IM, Menache MG. Mechanisms of particulate matter toxicity in neonatal and young adult rat lungs. Research Report, Health Effects Institute, 2008, Report Number 135. R832414C003 (2009)
R832414C003 (Final)

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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