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Extramural Research

Genetics of Phthalate and Bisphenol A Risk in Minority Populations (Individual Susceptibility)

EPA Grant Number: R831711C003
Subproject: this is subproject number 003 , established and managed by the Center Director under grant R831711
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Mount Sinai Center for Children’s Health and the Environment
Center Director: Wolff, Mary S.
Title: Genetics of Phthalate and Bisphenol A Risk in Minority Populations (Individual Susceptibility)
Investigators: Wetmur, James G.
Current Investigators: Wetmur, James G. , Chen, Jia , Wolff, Mary S.
Institution: Mount Sinai School of Medicine
EPA Project Officer: Callan, Richard
Project Period: November 1, 2003 through October 31, 2008 (Extended to October 31, 2010)
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003)
Research Category: Children's Health , Health Effects

Description:

Objective:

The objective of this research project is to study seven genetic polymorphisms in the enzymes that activate and detoxify organophosphates and other pesticides in the population of mothers and infants enrolled in project R831711C002.

Publications and Presentations:

Publications have been submitted on this subproject: View all 93 publications for this subprojectView all 254 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 52 journal articles for this subprojectView all 118 journal articles for this center

Supplemental Keywords:

lipase, paraoxonase, pesticides, haplotyping technology, polymorphisms, endocrine disruptors, EDs, neurodevelopment, minority populations,, RFA, Health, Scientific Discipline, ENVIRONMENTAL MANAGEMENT, POLLUTANTS/TOXICS, Environmental Chemistry, Health Risk Assessment, Chemicals, Endocrine Disruptors - Environmental Exposure & Risk, endocrine disruptors, Biochemistry, Children's Health, Endocrine Disruptors - Human Health, Risk Assessment, pesticide exposure, environmental health, childhood development, endocrine disrupting chemicals, exposure studies, pesticides, phtalates, Human Health Risk Assessment, genetic polymorphisms, children's vulnerablity, neurodevelopmental toxicity, exposure pathways, children's environmental health

Progress and Final Reports:
2004 Progress Report
2005 Progress Report
2006 Progress Report
2007 Progress Report
Final Report


Main Center Abstract and Reports:
R831711    Mount Sinai Center for Children’s Health and the Environment

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R831711C001 Growing Up Healthy in East Harlem (Community-Based Participatory Research)
R831711C002 Pesticides, Endocrine Disruptors, Childhood Growth and Development (Birth Cohort)
R831711C003 Genetics of Phthalate and Bisphenol A Risk in Minority Populations (Individual Susceptibility)

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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