Jump to main content or area navigation.

Contact Us

Extramural Research

Final Report: Inner City Toxicants, Child Growth and Development

EPA Grant Number: R831711
Center: Mount Sinai Center for Children's Environmental Health and Disease Prevention Research.
Center Director: Wolff, Mary S.
Title: Inner City Toxicants, Child Growth and Development
Investigators: Wolff, Mary S. , Brenner, Barbara , Chen, Jia , Claudio, Luz , Engel, Stephanie M. , Galvez, Maida , Godbold, James , Teitelbaum, Susan , Wetmur, James G.
Institution: Mount Sinai School of Medicine
EPA Project Officer: Callan, Richard
Project Period: November 1, 2003 through October 30, 2008 (Extended to October 30, 2010)
Project Amount: $4,004,980
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003)
Research Category: Children's Health , Health Effects , Human Health

Description:

Objective:

The Mount Sinai Center for Children's Environmental Health and Disease Prevention Research, titled "Inner City Toxicants, Child Growth and Development," is an interdisciplinary research and translation Center jointly funded by NIEHS and EPA since 1998. The Center is based in East Harlem, New York City. East Harlem is an 88% minority community where 39% of households live in poverty. Infant mortality in East Harlem is 42% higher than in the rest of New York City (9.6 v 6.7 per 1,000 births), life expectancy at birth is 10 years shorter, and more than 40% of 5-year-old children are overweight or obese (body mass index above the 85th percentile nationally), a rate three times the national norm. Environmental exposures in these children often are higher than in other parts of our city and nation. Research in our Center has focused, since the Center’'s inception, on discovery of the potentially preventable, environmental risk factors for childhood disease in the urban environment.
 
During the first five years of the Center (1998-2003), we focused our research on exposures to pesticides and PCBs, known neurotoxicants whose distribution in the urban environment then was uncharacterized. We documented that exposures were widespread.
 
This study also includes subprojects 1-3, the progress for which is in the Final Reports for Grant Nos. R831711C001, R831711C002, and R831711C003.

 

Summary/Accomplishments (Outputs/Outcomes):

We characterized children's exposures to pesticides, polychlorinated biphenyls (PCBs), DDT, chlordane, and lead in three birth cohorts from East and Northern Harlem, New York City. We also evaluated susceptibility factors related to certain exposures. With the East Harlem community, we developed, deployed, and field tested integrated pest management methods to reduce children's exposures to neurotoxic pesticides. In a population of African-American men whose mothers had participated in the Collaborative Perinatal Project during the 1960s, we measured in utero exposure to PCBs and found associated decrements in intelligence that were still evident at age 17 years. Timing of pubertal development now is being studied in that and in a new cohort. PCBs, but not DDE, were strongly associated with income, a socioeconomic status indicator, in this cohort. In two recently established (1998-2001) East Harlem birth cohorts, we found evidence for common (but not universal) exposure to organophosphate and pyrethroid pesticides. Exposures to PCBs and related chlorinated hydrocarbons were quite low, but PCB levels were still associated with fish intake. Lead (Pb) exposures were low. Neurotoxic effects of prenatal organophosphate exposures also were mediated by PON1.
 
Project 2 (R831711C002), The New York Children's Environmental Health Study, found that prenatal exposures to organophosphate insecticides had deleterious effects on infant and child neurobehavioral development and size at birth. Project 2 demonstrated that variation in maternal genotypes and phenotype of PON1 could modulate these effects. In utero exposure to organophosphates was associated with decreased head size of infants at birth, but only in mothers with low PON1 activity. Project 1 (R831711C001) demonstrated the feasibility of reducing organophosphate exposure in the urban environment through introduction of integrated pest management. During this period, a marked decline in pesticide and PCB exposures occurred in the United States due to legislative banning of residential use of chlorpyrifos and diazinon.
 
In the last five years (2004-2010), we made a strategic shift in the Center from the study of pesticides and PCBs to research on prevalent endocrine disruptors (EDs) - phthalates and phenols, including bisphenol A. The scientific theme for the second cycle of Center funding, years 6-10, was EDs, their sources, relationship to diet, physical activity, somatic growth, childhood obesity, and neurobehavioral development in the urban environment. During that time, we continued to follow the birth cohorts established in the first grant cycle, to evaluate effects on later childhood development of the prenatal pesticide/PCB exposures as well as the newly measured prevalent ED exposures. We have presented our findings internationally, both our own data and findings comparing our data to those from the other Children's Centers. The Research Strategy during this cycle was to examine exposures and outcomes in two windows of development (Projects 1 and 2), and to examine susceptibility factors that might alter those associations, including the built-environment, diet, physical activity, and genetic variability in phase I and II enzymes that govern metabolism and detoxification of the EDs of interest (Project 3, R831711C003).
 
The ED chemicals, characterized by weak hormonal activity, have become pervasive in the modern environment. When we began this research, there was no information available on their effects on human health. We made seminally important contributions in our second funding cycle to scientific knowledge about associations between ED exposures, neurodevelopmental disorders, and childhood obesity.
  • We found among children in East Harlem that exposures to multiple known and potential developmental toxicants - a new generation of environmental EDs for which there was little evidence - are ubiquitous. However, while phthalate biomarker levels were universally high (medians > 100 ug/L), bisphenol A levels were low (medians < 3 μg/:L) and other phenols were 20-50 times higher (BP3, parabens, 25DCP).
  • We identified sources of these exposures among children and mothers in our cohorts and showed that urinary levels in children are relatively stable over a year's time.
  • We characterized elements of the East Harlem neighborhood structure that contribute to disparities in food intake and availabilty as well as physical activity resources.
  • We observed modulation of these exposures by metabolizing genes.
  • We discovered for the first time that prenatal exposures to EDs have adverse effects on birth outcomes.
  • We discovered for the first time that prenatal exposures to EDs have adverse impacts on children's neurodevelopment, from birth to age 7 years.
  • We extended previous research on pesticide exposures and child behavior with new findings through age 9.
  • We found that EDs are linked to childhood obesity, thus confirming similar, earlier reports in adults linking phthalates to obesity.
  • We observed possible modulation by diet and socioeconomic factors of child ED exposures in relation to obesity and possibly metabolic syndrome.
  • We discovered previously unrecognized associations between ED exposures and (1) gene dysregulation and (2) disruption of the epigenome.
  • We confirmed additional effects of pesticides and PCBs on child development at later ages.
  • We demonstrated an association of maternal hormone determinants and child behavior.
  • We clarified relationships between exposures and outcomes in both the prenatal and the postnatal  windows of childhood.
  • Through the Community Outreach and Translation Core, we built strong links with the community, and fully engaged both the researchers in the Center and community members and participants into current topics of children's environmental health. With our Community Advisory Board, we worked to provide information on exposures, health outcomes, and the built-environment to study participants and the community at large. 
Final Reports for the Community Outreach and Translation Core (COTC) and Support Cores
 
Community Outreach and Translation Core
The Community Outreach and Translation Core in the Mount Sinai CEHC provided educational and outreach activities to study participants in the epidemiological projects in order for the community to receive direct benefits from the study. These activities had the additional goal to enhance recruitment and retention of participants in the study by providing additional incentives for long-term participation. The COTC has two main forms of interaction with study participants: workshops and print communications. The COTC is identified by the Project 1/CBPR logo and the child logo, designed by a community student and an East Harlem artist.
 
Print Communications:  The COTC created 20 fact sheets about environmental exposures and health issues in East Harlem aimed at study participants and East Harlem residents, using original print materials created specially for this population. The CORE also published a bi-annual newsletter that informs participants of the progress of the center studies and fact sheets that take one topic in pediatric environmental or community health and presented its relevance to the community. These mailings often were accompanied with materials specifically designed to reinforce the environmental health messages for participants. In addition, fact sheets and other materials created by the COTC were distributed broadly throughout the community. Topics included safer plastics, mercury in fish (and safe-eating fish), locations/maps of playgrounds, free summer activities, and food markets.
 
Workshops for Study Participants:  The COTC partnered with community-based organizations that have expertise in providing quality supplemental education for minority children and their families. Partner community-based organizations included New York City Parks Foundation and Little Sisters of the Assumption. The community partners facilitated organization of activities and review outreach materials. These in-person events including workshops and incentive give-away activities provided opportunities to reach lost-to-follow up participants for the Epidemiological Study. For instance, the 2008 Back to School outreach program resulted in 54 completed visits. Many research subjects who had been thought to be lost to follow-up were identified and brought back to the study by using these incentives. Invitations were sent to study participants in Projects 1 and 2, and were linked to study visits when possible, to improve follow-up completion. Events included Park events, Salsa dance party, Art Day, Halloween Party, Holiday Photo Studio (held near Christmas to create personal holiday cards), science workshops, picnic with recipe/nutritional workshops, and educational workshops with the Department of Education on pubertal development.
 
Retention of participants in urban research studies is a challenge, particularly among minorities and among immigrant populations. Our community includes a large proportion of recently arrived Central American women and children, who move and who maintain limited telephone contact. These outreach efforts have improved retention, and have pleased the participants who are eager for better information about child health and development.
 
Selected citations: Claudio, Environmental Health Perspectives 2005; Claudio, Prevention Magazine 2008, Claudio and Stingone, Journal of Health Care for the Poor and Underserved.
 
Administrative Core
The Administrative Core led and coordinated all aspects of the Center's work. The Core was led by Dr. Mary Wolff, Director of the Mount Sinai Center for Children’s Environmental Health and Disease Prevention Research, in close consultation with Dr. Philip Landrigan. Dr. Trudy Berkowitz was a Co-PI from 1998 until her retirement in 2003. The Core successfully recruited young investigators who now are leaders in the field of endocrine exposures and childhood health. The Core collaborated with other Children's Environmental Health Centers across the United States to develop strategies for pooling data across Centers. We directed the activities of the Internal and External Advisory Boards, and coordinated the Center's research with the East Harlem community. The Core provided leadership for cross-project research, intellectual enrichment, fiscal and personnel management, scientific activities, and communication with NIEHS/EPA. The Core played a prominent role nationally and internationally in promoting research and enhancing appreciation of the importance of children’s' environmental health among both the general public and policy makers. Under Dr. Landrigan's leadership, the Department was designated a World Health Organization Collaborating Centre in Children's Environmental Health. The new links established in 2003 with the Pediatric Environmental Health Specialty Unit at Mount Sinai provided an extremely effective means of translation to the community and to pediatricians.
 
Biostatistics and Data Management Core
Biostatistics Core Members have worked closely with investigators in all projects of the Mount Sinai Children's Environmental Health Center. This core has been able to provide a shared resource in biostatistical services, including consultation in study design, statistical analysis, and interpretation of results. During the project period, the Core convened weekly data meetings that are attended by investigators in the Projects and biostatisticians. In these meetings, the analyses performed in the previous week are reviewed, and new analyses for the upcoming week are specified. This mechanism has worked well to keep investigators and biostatisticians focused and on track regarding data analysis. In particular, Mr. Zhu and Ms. McGovern have done analyses for biomarker papers with Dr. Wolff, analyses for Dr. Galvez's papers on physical activity resources, and analyses for Dr. Teitelbaum's paper on product use and physical activity. They have created a pooled dataset for multiple centers at University of California-Berkeley, University of Cincinnati, Columbia University, and Mount Sinai; created and cleaned datasets for novel genes genotyping and folate gene genotyping; analyzed data on AIMs on Growing Healthy Girls; assembled a covariate dataset for the analysis on Growing Up Healthy Girls for investigators at Roswell Park; built predictive and adjustment models to study associations between LUMA and biomarkers; created and cleaned the CYPGENE-biomarker dataset and assisted Amir and Dr. Wolff in analysis; and conducted analysis of the data on lipase genes. Ms. Moshier has maintained tracking databases, adding queries, forms, and reports as required; monitored data entry practices and resolved problems the staff encountered related to data entry; supervised double-key data entry practices, comparing first and second entry databases and generating a list of discrepancies; performed routine data cleaning of the tracking database; and performed statistical analyses of body-size measures and phthalate/phenol biomarkers.
 
An additional aim of this Core has been to provide opportunities for education in biostatistical methods that integrate diverse domains of environmental health research. In fulfilling this aim, the BDM Core has led a Biometry Journal Club to discuss papers from the biostatistical and epidemiological literature, focusing on new methods or novel application of existing methods. The Core assisted Center Members in continuing education opportunities for data management and statistical analyses. The main aim of the Core has been to coordinate data collection, computer storage, management, and statistical analyses. This involved a large number of databases created and maintained by this Core.
 
Members of the Core are included as co-authors on all papers involving data analysis, as appropriate.
 
Exposure Assessment Core
The Exposure Assessment Core contributed significantly to various aspects of the Core and have worked closely together to integrate all aspects of the exposure biomarker and interview measurements into the three Research Projects. During the Center's lifetime, the Core monitored specimen collection, storage, and shipping for all Projects. The core relied heavily on biomarkers of exposure for mothers and children, including organochlorines, elemental lead, organophosphate and carbamate pesticides, PCBs, phthalates, and phenols. PFC, perchlorate and related anions also were measured (preliminary data). Blood lipids and urinary creatinine were measured in serum for Projects 2 and 3. The laboratory at Mount Sinai provided support to all projects for pesticide, PCB, and lead measurements. The Core coordinated activities with the Centers for Disease Control and Prevention (CDC) Laboratories (Dr. Dana B. Barr and Dr. Antonia Calafat) for analysis of urinary pesticides, phenols, PFCs, and phthalate metabolites. The Core also provided support for quality control/quality assurance for laboratory measures.
 
Over the past six years, the Exposure Assessment Core has provided analytical and logistical support for sample analyses and field survey methods in research Projects 1, 2, and 3 and has processed samples for analysis of organochlorines, lead in blood, creatinine, lipids, phthalate metabolites (CDC), phenols (CDC), and perchlorate (CDC). These analyses were done in all or a subset of the 500 children in Project 1 and the 404 mothers in Project 2, and on more than one specimen type and multiple specimens per subject.
 
Appropriate quality control measures were incorporated into all field collections and laboratory, analytical methods, to the extent of approximately 10% of the field samples. The lab was blinded as to case-control or QC status of urine samples. In the CDC analyses, the field QCs were reviewed immediately on receipt of data and were reported back to CDC. In the case of a strange outlier, the batch was repeated by CDC; this happened once for one analyte. Quality control also is monitored routinely by the CDC labs using the system quality control samples at a rate of about 10%. QC results are reported with each published study as a compilation of data for the entire study dataset, which may include accuracy (i.e., recovery or target levels), reproducibility within and between batches, and the limit of detection (computed as three times the standard deviation of blanks or of essentially zero-level matrix material, such as pooled urine or serum).
 
Representative publications utilizing data coordinated through the Exposure Assessment Core include Berkowitz, et al., 2003, 2004; Borrell, et al., 2004; Engel, et al., 2006, 2007, 2009, 2010; Fenske, et al., 2005; Lamb, et al., 2006; Liu, et al., 2006; Longnecker, et al., 2003; Miodovnik, et al., 2010; Teitelbaum, et al., 2008, 2011, 2009; Wolff, et al., 2005, 2007a, 2007b, 2008.
 
Final Reports for Two New Investigators
 
To encourage new investigators in children's environmental health research, each Children's Center was required to provide at least partial support to at least one newly recruited Center scientist. From 2003-2010, two new Investigators participated in the Center's research, Maida Galvez, MD and Susan Teitelbaum, PhD. 
 
New Investigator:  Maida Galvez, MD was the first full-time Clinical Pediatrician working in the Center in clinical pediatric research.
 
Goals and Specific Aims
 
Dr. Galvez has identified environmental factors both in the urban built environment as well as ED exposures, and their effects on children’'s growth and development as a particular area of interest. Her goal is to work in partnership with an interdisciplinary team of researchers, contributing her clinical expertise in Environmental Pediatrics, to enhance our understanding of potentially modifiable environmental exposures that can impact children's health.
 
Specific Aims were to:
  •      Characterize the Urban Built Environment of East Harlem, NY and early childhood ED exposures in a cohort of East Harlem children ages 6-8 years old.
  •      Determine whether built environment factors and early childhood ED exposures are associated with childhood obesity.
  •      Utilize a community based participatory research framework to guide the overall study design.
  •      Communicate study findings to families, the East Harlem community, health care providers and public health officials to inform both clinical and public health interventions.
Final Report:
During the past 6 years, Dr. Galvez continued to be one of the principal contributors overseeing data collection for Project 1, particularly in the area of the built environment. Dr. Galvez worked closely with Dr. Brenner (PI, Project 1), Dr. Wolff (Center Director) and Dr. Teitelbaum (Co-I). She also collaborated with community partners including the New York City Department of Health’s Geographic Informations Systems (GIS) Center in order to characterize and assess the impacts of the East Harlem urban built environment on children’'s diets, physical activity levels and risk for obesity.
 
Dr. Galvez made several important findings in her community-based, participatory research. These findings have clear implications for translation to the community-based prevention of obesity (see Project 1 [R831711C001], Final Report). Thus she observed that children who lived on the same block as convenience food stores were more likely than other children from the same community to be obese (presented at the 2008 Pediatric Academic Society Meeting and published in Academic Pediatrics Journal, 2009). She and her team also found that the presence of fast food stores in the same census tract as a child’'s home increased the likelihood that a child would exceed dietary recommendations for total fat and saturated fat consumption. These findings have been presented to parents, community groups, policy makers, and health care providers within the East Harlem community as well as in regional, national and international settings (e.g., ISEE 2008).
 
Significance:  Dr. Galvez developed a career in Environmental Pediatric Health and research that bridges clinical and etologic research in pediatric environmental health. She has worked extensively in the past 5 years in order to ensure Center study findings are shared with the larger community in the broadest senses of the term, with families, health care providers, trainees, community-based organizations, and public health officials. Much of this work was done in collaboration with the ATSDR-supported Mount Sinai EPA Region 2 PEHSU, which Dr. Galvez now directs as well as with the COTC led by Dr. Luz Claudio and the Growing Up Healthy in East Harlem Community Advisory Board led by Dr. Barbara Brenner.
 
Plans:  Baseline data analyses are being finalized and Dr. Galvez will continue to assess the longitudinal relationships between children's environmental exposures in the urban built environment and subsequent impacts on diet, physical activity level and risk for obesity. Dr. Galvez recently was awarded competitive funding through the New York State Empire Clinical Research Investigator Program (ECRIP) for the years 2009-2011 to further extend her research. This New York State grant complemented the support that she receives through the Children's Center. In a parallel cohort of New York City girls enrolled in the Breast Cancer and the Environment Research Consortium (BCERC) in which she is a Co-Investigator, Dr. Galvez will be able to assess impacts of the urban built environment on early onset of puberty in a racially/ethnically and economically diverse cohort of 6-8 year old girls from New York, Ohio and California. She also has received a scholarship to train with renowned experts at the Built Environment Assessment Training (BEAT) Insitutue Conference in San Diego in June 2009.
 
In an effort to address urban environmental factors that influence children's risk for obesity. Dr. Galvez has partnered with Bette Midler's New York Restoration Project, Sustainable South Bronx and Solar One to create environmental education programs that offer opportunities to (1) reconnect with nature, (2) increase inner city children's time spent outdoors and (3) increase physical activity levels in existing green spaces in East Harlem.
 
These efforts, entitled the "Green Stops Partnership," received foundation support in 2009.
 
Publications include Galvez, et al., 2003, 2007, 2009, 2009, 2010; Teitelbaum, et al., 2008; Sheffield and Galvez, 2010; Landrigan, Rauh and Galvez, 2010.

Project Generated Resources:
            1. Dr. Galvez collaborated on the National PEHSU Fact Sheet on Phthalates and BPA, one geared             towards providers and another for patients. These fact sheets are available online in English and Spanish at:            http://aoec.org/PEHSU/documents/bpa_provider_july_8_08.pdf

                http://aoec.org/PEHSU/documents/bpa_patient_july_8_08.pdf

            2. Dr. Galvez served also on a National Research Council Committee convened by EPA to address             approaches to assessing cumulative environmental exposures in childhood, using phthalates as a case             study: Phthalates and Cumulative Risk Assessment, the Tasks Ahead. Washington DC: National             Research Council, 2008.

3. Phthalates and Cumulative Risk Assessment: The Tasks Ahead. National Research Council. Committee on Health Risks of Phthalates: Cory-Schlecta D, Crouch E, Foster P, Fox M, Gaido K, Galvez MP, Gennings C, Gilman J, Hauser R, Kortenkamp A, Peters J, Vorhees D, Wolff M. The National Academies Press, 2008.

New Investigator: Susan Teitelbaum, PhD is an epidemiologist with an M.S. degree in biostatistics and with extensive expertise in environmental exposures. She obtained her Ph.D. in epidemiology from Columbia University.

Final Report:
During her New Investigator period, she has applied her expertise to assessing the validity and utility of environmental biomarkers in children, and investigating their sources of exposure. She has also developed mixed exposure models in children. In her Center capacity as an exposure ascertainment expert, she has advised Project 2 on exposure issues and worked closely with the Exposure Core on implementing measurements and pilot studies. She also became involved with Project 3 by leading the statistical analysis of the AIMs study on racial/ethnic adjustment in analytic models. Her Aims as a New Investigator were (1) to apply advanced statistical techniques not yet commonly used by epidemiologists, such as factor analysis and multilevel modeling, for investigating multiple and multilevel exposures in environmental epidemiology; (2) to improve the questionnaire assessment of ED exposure (to be used in Projects 1 and 2) with the goal of developing a valid and reliable questionnaire-based exposure ascertainment instrument; (2) to examine the combined multiple exposures of the urban built environment and their relationship with obesity among the children of East Harlem, NY (CBPR – Project 1) and on growth and development among the children in Project 2.

Dr. Teitelbaum also became the principal overseer of field operations and data collection for Project 1, including detailed training and methods of data collection and analysis. Dr. Teitelbaum working closely with Project 1 and the Exposure Assessment Core, conducted the Specific Aim of Project 1 to assess the temporal variability of the biomarker levels measured by the CDC in the urine samples collected in the pilot project for Project 1.  In addition, data analysis has been completed to assess the relationship between biomarker level and reported product use from the questionnaire data collected during the pilot study.  Preliminary data provided in Project 1’s Progress report showed that certain phthalate biomarkers in children are related to reported use of scented products.  Dr. Teitelbaum completed an advanced statistical course in mixed models and she has also been involved in the statistical analysis of the multiple pesticide metabolite data from Project 2. She has provided statistical expertise in the Project 3 study of racial/ethnic variability and AIMS, a genetic alternative to personal declaration for assessing ancestry; she led the analysis and writing of this paper (see Project 3). She has taken a leadership role in the companion project on environment and puberty in girls, and NIEHS/NCI initiative, and has spoken widely both nationally and internationally on children’s environmental exposures, and especially those that hormonally active.

Significance:  Dr. Teitelbaum’s New Investigator award has allowed her to extend her excellent training in environmental epidemiology, which had been focused previously only on cancer, to childhood and pregnancy. It has positioned her to be a leader in evaluation of children’s environmental exposures, and thus, based on her publications, abstracts, and lectures has achieved the goal of the New Investigator program. In addition, the results of her research have had an important impact on exposure assessment in children. The temporal variability analysis of phthalate metabolites, phytoestrogens and phenols provides good evidence that the sources of exposure for these chemicals are relatively constant over the previous six to twelve months.  For 13 biomarkers the six-month average concentration was predicted by a sample collected at the start of the interval as well as by a sample collected at the end of the interval, suggesting that an annual urine sample used for exposure assessment in longitudinal studies might be reflective of a participant’s year-long exposure for these chemicals. Few data on validity of biomarkers of this kind exist, and they are urgently needed. The pilot study has also provided important information on environmental sources of the endocrine disruptors.  Past week use of several personal care products (e.g., shampoo, hair gel, and body moisturizer) was significantly associated with higher concentrations of several metabolites of di-2-ethylhexyl phthalate (DEHP).  Reported use of sunscreen was significantly associated with higher concentrations of BP3, an ultraviolet filter.  In order to appreciate whether other new chemicals should be part of our research program, she established a collaboration with CDC to measure perchlorate, iodide in the temporal variability samples and in the proposed Center Renewal for Projects 1 and 2.

Major publications include Engel et al. 2007; Lee et al. 2010; Teitelbaum et al. 2008.

 

Conclusions:

The medical and public health significance of the endocrine disruptor (ED) exposures that we have studied is potentially enormous. These chemicals are widespread in the urban environment and are detected at high levels in the body of virtually every mother and child whom we have examined. Both our preliminary data and the published literature indicate that these chemicals have potential to adversely affect human development across a broad range of exposure levels. If, like lead and PCBs, they increase neurodevelopmental dysfunction, and if also they increase risk of obesity, the impacts may be lifelong. Although the biological activity of these chemicals may be lower than their already banned predecessors (i.e., lead, chlorpyrifos, diazinon, PCBs), their public health consequences may in fact be greater given the tremendous magnitude of exposure to them in the general population. Therefore, the aggregate cost to society may be enormous, as was the case two decades ago with widespread exposure of the U.S. population to lead.


Journal Articles: 118 Displayed | Download in RIS Format

Other center views: All 254 publications 140 publications in selected types All 118 journal articles

Type Citation Sub Project Document Sources
Journal Article Anderson HA, Wolff MS. Special fish contaminants issue. Environmental Research 2005;97(2):125-126 (introductory commentary). R831711 (2004)
R831711 (2005)
R831711 (2006)
R831711 (2007)
R831711 (Final)
R831711C001 (2006)
R831711C002 (2006)
R831711C003 (2006)
R830254 (Final)
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Belogolovkin V, Engel SM, Ferrara L, Eddleman KA, Stone JL. Does sonographic determination of placental location predict fetal birth weight in diamniotic-dichorionic twins? Journal of Ultrasound in Medicine 2007;26(2):187-191. R831711 (2007)
  • Abstract from PubMed
  • Abstract: Journal of Ultrasound in Medicine
    Exit
  • Journal Article Berkowitz GS, Obel J, Deych E, Lapinski R, Godbold J, Liu Z, Landrigan PJ, Wolff MS. Exposure to indoor pesticides during pregnancy in a multiethnic, urban cohort. Environmental Health Perspectives 2003;111(1):79-84. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R827039 (2002)
    R827039C004 (2002)
  • Full-text from PubMed
  • Abstract from PubMed
  • Other: EBSCO Host Connection - Abstract
    Exit
  • Journal Article Berkowitz GS, Wetmur JG, Birman-Deych E, Obel J, Lapinski RH, Godbold JH, Holzman IR, Wolff MS. In utero pesticide exposure, maternal paraoxonase activity, and head circumference. Environmental Health Perspectives 2004;112(3):388-391. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2004)
    R831711C002 (2006)
    R831711C003 (2004)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Other: The Free Library - Full Text HTML
    Exit
  • Journal Article Bienenfeld LA, Golden AL, Garland EJ. Consumption of fish from polluted waters by WIC participants in east Harlem. Journal of Urban Health 2003;80(2):349-358. R831711 (2005)
    R831711 (2007)
  • Abstract from PubMed
  • Journal Article Biro FM, Galvez MP, Greenspan LC, Succop PA, Vangeepuram N, Pinney SM, Teitelbaum S, Windham GC, Kushi LH, Wolff MS. Pubertal assessment method and baseline characteristics in a mixed longitudinal study of girls. Pediatrics 2010;126(3):e583-e590. R831711 (Final)
  • Abstract from PubMed
  • Full-text: Pediatrics-Full Text HTML
    Exit
  • Abstract: Pediatrics-Abstract
    Exit
  • Other: Pediatrics-Full Text PDF
    Exit
  • Journal Article Borrell LN, Factor-Litvak P, Wolff MS, Susser E, Matte TD. Effect of socioeconomic status on exposures to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) among pregnant African-American women. Archives of Environmental Health 2004;59(5):250-255. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: Taylor&Francis Online-Abstract
    Exit
  • Journal Article Braganza SF, Galvez MP, Mencin AA, Ozuah PO. Weighting the appropriate uses of supplemental zinc. Contemporary Pediatrics 2006;23(7):66-74. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text: Contemporary Pediatrics Full Text
    Exit
  • Abstract: Modern Medicine
    Exit
  • Journal Article Braganza SF, Galvez MP, Ozuah PO. Part two: When parents ask about diet therapy for ADHD. Contemporary Pediatrics 2006;23(5):47-49 R831711 (2007)
    not available
    Journal Article Braganza SF, Galvez MP, Ozuah PO. When parents ask about diet therapy for ADHD. Contemporary Pediatrics 2006;23(5):47-49. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text: Contemporary Pediatrics Full Text
    Exit
  • Journal Article Brand SR, Engel SM, Canfield RL, Yehuda R. The effect of maternal PTSD following in utero trauma exposure on behavior and temperament in the 9-month-old infant. Annals of the New York Academy of Sciences 2006;1071:454-458. R831711 (2007)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Brenner BL, Markowitz S, Rivera M, Romero H, Weeks M, Sanchez E, Deych E, Garg A, Godbold J, Wolff MS, Landrigan PJ, Berkowitz G. Integrated pest management in an urban community: a successful partnership for prevention. Environmental Health Perspectives 2003;111(13):1649-1653. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2004)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Journal Article Britton JA, Teitelbaum SL, Wolff MS. Correspondence re:Schoen et al., Lack of association between adipose tissue distribution, and insulin-like growth factor-I and insulin-like growth factor binding protein-3 in men and women. Cancer Epidemiol. Biomark. Prev., 11:581-586, 2002. Cancer Epidemiology, Biomarkers & Prevention 2003;12(6):586. R831711 (2007)
  • Full-text: Cancer Epidemiology, Biomarkers and Prevention-Full Text HTML
    Exit
  • Abstract: Cancer Epidemiology, Biomarkers and Prevention
    Exit
  • Other: Cancer Epidemiology, Biomarkers and Prevention-Full Text PDF
    Exit
  • Journal Article Britton JA, Wolff MS, Lapinski R, Forman J, Hochman S, Kabat GC, Godbold J, Larson S, Berkowitz GS. Characteristics of pubertal development in a multi-ethnic population of nine-year-old girls. Annals of Epidemiology 2004;14(3):179-187. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Annals of Epidemiology-Abstract
    Exit
  • Journal Article Chemtob CM, Conroy DL, Hochauser CJ, Laraque D, Banks J, Schmeidler J, Dela Cruz M, Nelsen WC, Landrigan PJ. Children who lost a parent as a result of the terrorist attacks of September 11, 2001: registry construction and population description. Death Studies 2007;31(1):87-100. R831711 (2007)
  • Abstract from PubMed
  • Abstract: Informaworld-Abstract
    Exit
  • Journal Article Chen A, Zhang J, Zhou L, Gao E, Chen L, Rogan WJ, Wolff MS. DDT serum concentration and menstruation among young Chinese women. Environmental Research 2005;99(3):397-402. R831711 (2005)
    R831711 (2007)
  • Abstract from PubMed
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Chen J, Kumar M, Chan W, Berkowitz G, Wetmur JG. Increased influence of genetic variation on PON1 activity in neonates. Environmental Health Perspectives 2003;111(11):1403-1409. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2004)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Chen J, Chan W, Wallenstein S, Berkowitz G, Wetmur JG. Haplotype-phenotype relationships of paraoxonase-1. Cancer Epidemiology Biomarkers & Prevention 2005;14(3):731-734. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: AACR-Full Text HTML
    Exit
  • Abstract: AACR-Abstract
    Exit
  • Other: AACR-Full Text PDF
    Exit
  • Journal Article Claudio L. Breast cancer takes center stage. Environmental Health Perspectives 2004;112(2):A92-A95 (NIEHS News). R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Journal Article Claudio L. Making progress on breast cancer. Environmental Health Perspectives 2006;114(2):A98-A99 (NIEHS News). R831711 (2005)
    R831711 (2006)
    R831711 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Full-text: Environmental Health Perspectives-Full Text HTML
  • Journal Article Claudio L, Stingone JA, Godbold J. Prevalence of childhood asthma in urban communities: the impact of ethnicity and income. Annals of Epidemiology 2006;16(5):332-340. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Elsevier-Abstract
    Exit
  • Journal Article Claudio L, Stingone J. Improving sampling and response rates in children's health research through participatory methods. Journal of School Health 2008;78(8):445-451. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Cohn BA, Cirillo PM, Wolff MS, Schwingi PJ, Cohen RD, Sholtz RI, Ferrara A, Christianson RE, van den Berg BJ, Siiteri PK. DDT and DDE exposure in mothers and time to pregnancy in daughters. Lancet 2003;361(9376):2205-2206. R831711 (2007)
  • Abstract from PubMed
  • Journal Article Cohn BC, Cirillo PM, Wolff MS, Schwingl PJ, et al. In utero DDT and DDE exposure may alter time to pregnancy in daughters 30 years later. Lancet 2003;361(9376):2205-2006. R831711 (2005)
    not available
    Journal Article Dietrich KN, Eskenazi B, Schantz S, Yolton K, Rauh VA, Johnson CB, Alkon A, Canfield RL, Pessah IN, Berman RF. Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1437-1446. R831711 (2005)
    R827027 (2002)
    R829388 (2006)
    R829388 (Final)
    R829388C006 (2005)
    R829389 (2005)
    R829389 (Final)
    R829390 (2005)
    R829390 (Final)
    R829390C002 (2005)
    R831710 (2005)
    R831710 (Final)
    R832141 (2006)
    R832141 (2007)
    R832141 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Diplas AI, Hu J, Lee M-J, Ma YY, Lee YL, Lambertini L, Chen J, Wetmur JG. Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. Nucleic Acids Research 2009;37(21):7039-7046. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Oxford Journals-Full Text HTML
    Exit
  • Abstract: Oxford Journals-Abstract
    Exit
  • Other: Oxford Journals-Full Text PDF
    Exit
  • Journal Article Dunson DB, Herring AH, Engel SM. Bayesian selection and clustering of polymorphisms in functionally related genes. Journal of the American Statistical Association 2008;103(482):534-546. R831711 (2007)
    R831711 (Final)
  • Abstract: American Statistical Association-Abstract
    Exit
  • Other: Duke-Prepublication PDF
    Exit
  • Journal Article Edwards ES, Green N, Henry CJ, Landrigan PJ, Swartz D. Tracking children's health to age 21. Science 2003;302(5646):781 (letter comment on Science 2003;301(5630):162-163). R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract:
    Exit
  • Journal Article Engel SM, Berkowitz GS, Yehuda R, Wolff MS. Psychological trauma associated with the World Trade Center attacks and its effect on pregnancy outcome. Paediatric and Perinatal Epidemiology 2005;19(5):334-341. R831711 (2007)
    R831711 (Final)
    R830827 (Final)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Engel SM, Levy B, Liu Z, Kaplan D, Wolff MS. Xenobiotic phenols in early pregnancy amniotic fluid. Reproductive Toxicology 2006;21(1):110-112. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C002 (2007)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Science Direct-Full Text HTML
    Exit
  • Abstract: Science Direct-Abstract
    Exit
  • Other: Science Direct-Full Text PDF
    Exit
  • Journal Article Engel SM, Olshan AF, Siega-Riz AM, Savitz DA, Chanock SJ. Polymorphisms in folate metabolizing genes and risk for spontaneous preterm and small-for-gestational age birth. American Journal of Obstetrics and Gynecology 2006;195(5):1231.e1-1231.e11. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Elsevier-Abstract
    Exit
  • Other: Science Direct-Abstract
    Exit
  • Journal Article Engel SM, Hertz-Picciotto I, Schramm M, Watt-Morse M. Recreational Physical Activity Practices Before and During Pregnancy. Obstetrics and Gynecology 2006. R831711 (2005)
    not available
    Journal Article Engel SM, Berkowitz GS, Barr DB, Teitelbaum SL, Siskind J, Meisel SJ, Wetmur JG, Wolff MS. Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort. American Journal of Epidemiology 2007;165(12):1397-1404. R831711 (2007)
    R831711 (Final)
    R831711C002 (2007)
    R831711C003 (2007)
  • Abstract from PubMed
  • Full-text: Oxford-Full Text HTML
    Exit
  • Abstract: Oxford-Abstract
    Exit
  • Other: Oxford-Full Text PDF
    Exit
  • Journal Article Engel SM, Janevic TM, Stein CR, Savitz DA. Maternal smoking, preeclampsia, and infant health outcomes in New York City, 1995-2003. American Journal of Epidemiology 2009;169(1):33-40. R831711 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Oxford Journals-Full Text HTML
    Exit
  • Abstract: Oxford Journals
    Exit
  • Other: Oxford Journals PDF
    Exit
  • Journal Article Engel SM, Zhu C, Berkowitz GS, Calafat AM, Silva MJ, Miodovnik A, Wolff MS. Prenatal phthalate exposure and performance on the Neonatal Behavioral Assessment Scale in a multiethnic birth cohort. NeuroToxicology 2009;30(4):522-528. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Science Direct-Full Text HTML
    Exit
  • Abstract: Science Direct-Abstract
    Exit
  • Other: Science Direct-Full Text PDF
    Exit
  • Journal Article Engel SM, Miodovnik A, Canfield RL, Zhu C, Silva MJ, Calafat AM, Wolff MS. Prenatal phthalate exposure is associated with childhood behavior and executive functioning. Environmental Health Perspectives 2010;118(4):565-571. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: EHP-Full Text HTML
  • Abstract: EHP
  • Journal Article Eskenazi B, Landrigan PJ. Environmental Health Perspectives and children's environmental health. Environmental Health Perspectives 2002;110(10):A559-A560. R831711 (2007)
  • Full-text: Environmental Health Perspectives-Full Text PDF
  • Journal Article Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2004)
    R831711C002 (2006)
    R831711C003 (2006)
    R827027 (2002)
    R829389 (2003)
    R829389 (2004)
    R829389 (2005)
    R829389 (Final)
    R829390 (2005)
    R829390 (Final)
    R829390C002 (2005)
    R831709 (2005)
    R831709C001 (2004)
    R831710 (2005)
    R831710 (Final)
    R831710C001 (2006)
    R831710C002 (2006)
    R832141 (2005)
    R832141 (2007)
    R832141 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Etzel RA, Crain EF, Gitterman BA, Oberg C, Scheidt P, Landrigan PJ. Pediatric environmental health competencies for specialists. Ambulatory Pediatrics 2003;3(1):60-63. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Science Direct
    Exit
  • Journal Article Etzel RA, Balk SJ, Reigart JR, Landrigan PJ. Environmental health for practicing pediatricians. Indian Pediatrics 2003;40(9):853-860. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Indian Pediatrics-Full Text
    Exit
  • Journal Article Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environmental Health Perspectives 2005;113(10):1455-1462. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R827027 (2002)
    R828609 (Final)
    R831709 (2005)
    R831709 (2007)
    R831710 (2004)
    R831710 (2005)
    R831710 (Final)
    R832141 (2006)
    R832141 (2007)
    R832141 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Fewtrell LJ, Pruss-Ustun A, Landrigan P, Ayuso-Mateos JL. Estimating the global burden of disease of mild mental retardation and cardiovascular diseases from environmental lead exposure. Environmental Research 2004;94(2):120-133. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Science Direct-Full Text HTML
    Exit
  • Abstract: Science Direct-Abstract
    Exit
  • Other: Science Direct-Full Text PDF
    Exit
  • Journal Article Galvez MP, Frieden TR, Landrigan PJ. Obesity in the 21st century. Environmental Health Perspectives 2003;111(13):A684-A685 (editorial). R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Journal Article Galvez MP, Peters R, Graber N, Forman J. Effective risk communication in children's environmental health:lessons learned from 9/11. Pediatric Clinics of North America 2007;54(1):33-46. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Elsevier-Abstract
    Exit
  • Journal Article Galvez MP, Morland K, Raines C, Kobil J, Siskind J, Godbold J, Brenner B. Race and food store availability in an inner-city neighborhood. Public Health Nutrition 2008;11(6):624-631. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2007)
  • Abstract from PubMed
  • Full-text: Cambridge Journals-Full Text HTML
    Exit
  • Abstract: Cambridge Journals-Abstract
    Exit
  • Other: Cambridge Journals-Full Text PDF
    Exit
  • Journal Article Galvez, MP, Graber NM, Sheffield PE, Forman JA , Balk SJ. Hot topics in environmental health. Child product safety: delivering guidance amid anxiety. Contemporary Pediatrics 2009;26(7):34-47. R831711 (Final)
  • Abstract: Modern Medicine-Abstract
    Exit
  • Journal Article Galvez MP, Hong L,Choi E, Liao L, Godbold J, Brenner B. Childhood obesity and neighborhood food-store availability in an inner-city community. Academic Pediatrics 2009;9(5):339-343. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: Academic Pediatrics-Abstract
    Exit
  • Journal Article Galvez MP, Pearl M, Yen IH. Childhood obesity and the built environment. Current Opinion in Pediatrics 2010;22(2):202-207. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: Current Opinion in Pediatrics-Abstract
    Exit
  • Journal Article Galvez M, Vanable L, Forman JA, Landrigan PJ, Akeredolu E, Leighton J, Nagin D. Childhood lead poisoning from commercially manufactured French ceramic dinnerware-New York City, 2003. Morbidity and Mortality Weekly Reports 2004;53(26):584-586. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: CDC-Full Text HTML
  • Abstract: CDC-Abstract
  • Other: CDC-Full Text PDF
  • Journal Article Garg A, Landrigan PJ. Children's environmental health: new gains in science and policy. Ann Am Acad Polit Soc Sci 2002;584(1):135-144. R831711 (2007)
  • Abstract: Sage Publications-Abstract
    Exit
  • Journal Article Godbold JH. Re:"Statistical analysis of correlated data using generalized estimating equations: an orientation." American Journal of Epidemiology 2003;158(3):289. R831711 (Final)
  • Full-text: Oxford Journals-Full Text
    Exit
  • Abstract: Oxford Journals-Abstract
    Exit
  • Other: Oxford Journals-Full Text PDF
    Exit
  • Journal Article Goldman L, Falk H, Landrigan PJ, Balk SJ, Reigart JR, Etzel RA. Environmental pediatrics and its impact on government health policy. Pediatrics 2004;113(Suppl 3):1146-1157. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Pediatrics-Full Text HTML
    Exit
  • Abstract: Pediatrics
    Exit
  • Other: Pediatrics-Full Text
    Exit
  • Journal Article Grandjean P, Landrigan PJ. Developmental neurotoxicity of industrial chemicals. Lancet 2006;368(9553):2167-2178. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Abstract: Lancet - Abstract
    Exit
  • Journal Article Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S. Community-based participatory research: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1463-1471. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R826710 (Final)
    R829391 (2004)
    R829391 (2005)
    R829391 (2006)
    R829391C005 (2006)
    R831709 (2005)
    R831709 (2007)
    R831709C003 (2005)
    R831709C003 (2006)
    R831710 (2004)
    R831710 (2005)
    R831710 (Final)
    R831710C001 (2006)
    R831710C002 (2006)
    R831710C004 (2006)
    R832139 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Kadlubar FF, Berkowitz GS, Delongchamp RR, Wang C, Green BL, Tang G, Lamba J, Schuetz E, Wolff MS. The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer. Cancer Epidemiology Biomarkers and Prevention 2003;12(4):327-331. R831711 (2005)
    R831711 (2007)
    R825816 (Final)
  • Abstract from PubMed
  • Full-text: Cancer Epidemiology, Biomarkers and Prevention-Full Text HTML
    Exit
  • Journal Article Lamb MR, Taylor S, Liu X, Wolff MS, Borrell L, Matte TD, Susser ES, Factor-Litvak P. Prenatal exposure to polychlorinated biphenyls and postnatal growth: a structural analysis. Environmental Health Perspectives 2006;114(5):779-785. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Lambertini L, Diplas AI, Lee MJ, Sperling R, Chen J, Wetmur J. A sensitive functional assay reveals frequent loss of genomic imprinting in human placenta. Epigenetics 2008;3(5):261-269. R831711 (2007)
    R831711 (Final)
    R831711C003 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Landes Bioscience-Full Text PDF
    Exit
  • Abstract: Landes Bioscience-Abstract
    Exit
  • Journal Article Lambertini L, Diplas AI, Wetmur J, Lee MJ, Chen J. Evaluation of genomic imprinting employing the analysis of Loss of Imprinting (LOI) at the RNA level:preliminary results. European Journal of Oncology 2009;14(3):161-169. R831711 (Final)
    not available
    Journal Article Landrigan PJ, Kimmel CA, Correa A, Eskenazi B. Children's health and the environment: public health issues and challenges for risk assessment. Environmental Health Perspectives 2004;112(2):257-265. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C003 (2006)
    R831710 (2004)
    R831710 (2005)
    R831710 (Final)
    R831710C001 (2004)
  • Full-text from PubMed
  • Abstract from PubMed
  • Journal Article Landrigan PJ, Slutsky J. Are learning disabilities linked to environmental toxins? Learning Disabilities: A Contemporary Journal 2004;15:7-12. R831711 (2005)
    R831711 (Final)
  • Full-text: Learning Disabilities Worldwide- Full Text HTML
    Exit
  • Other: Learning Disabilities Worldwide - Full Text PDF
    Exit
  • Journal Article Landrigan PJ, Lioy PJ, Thurston G, Berkowitz G, Chen LC, Chillrud SN, Gavett SH, Georgopoulos PG, Geyh AS, Levin S, Perera F, Rappaport SM, Small C, NIEHS World Trade Center Working Group. Health and environmental consequences of the World Trade Center disaster. Environmental Health Perspectives 2004;112(6):731-739. R831711 (2007)
    R831711C002 (2004)
    R827351 (2003)
    R827351 (Final)
    R830827 (2004)
    R830827 (Final)
    R832141 (2005)
    R832141 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Journal Article Landrigan PJ. Children as a vulnerable population. International Journal of Occupational Medicine and Environmental Health 2004;17(1):175-177. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Instytut Medycyny Pracy Im.-Full Text PDF
    Exit
  • Journal Article Landrigan PJ.Environmental threats to children’s health – the promise of the National Children’s Study. NECOEM Reporter 2005;2(13):1-2. R831711 (2005)
    R831711 (2007)
  • Full-text: New England College of Occupational and
    Environmental Medicine (NECOEM) - Full Text PDF

    Exit
  • Journal Article Landrigan PJ. Environmental exposures and children’s health challenges. Zero to Three 2005;26(2):8-10. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
  • Abstract: Education Resources Information Center (ERIC)-Abstract
  • Other: ZerotoThree-TOC
    Exit
  • Journal Article Landrigan PJ, Tamburlini G. Children's health and the environment: a transatlantic dialogue. Environmental Health Perspectives 2005;113(10):A646-A647. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Landrigan PJ, Sonawane B, Butler RN, Trasande L, Callan R, Droller D. Early environmental origins of neurodegenerative disease in later life. Environmental Health Perspectives 2005;113(9):1230-1233. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Landrigan PJ, Newman B. Children and other high-risk workers as a special challenge to occupational health services. SJWEH Supplements 2005;1:43-45. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text: SJWEH-Full Text PDF
    Exit
  • Abstract: SJWEH-Abstract
    Exit
  • Journal Article Landrigan PJ, Tamburlini G. Children’s health and the environment: a transatlantic dialogue. Environmental Health Perspectives 2005;113(10):A646-A647 (editorial). R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text: Environmental Health Perspectives Full Text
    Exit
  • Other: Environmental Health Perspectives PDF
    Exit
  • Journal Article Landrigan PJ, Trasande L. More kids chronically ill. Poughkeepsie Journal 2005. R831711 (2005)
    not available
    Journal Article Landrigan PJ. Environmental pediatrics and the ecological imperative. EcoHealth 2006;3(2):75-76 (editorial). R831711 (2005)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C003 (2006)
  • Full-text: EcoHealth-Full Text PDF
    Exit
  • Abstract: SpringerLink-Content Excerpt
    Exit
  • Journal Article Landrigan PJ, Trasande L, Thorpe LE, Gwynn C, Lioy PJ, D'Alton ME, Lipkind HS, Swanson J, Wadhwa PD, Clark EB, Rauh VA, Perera FP, Susser E. The National Children's Study: a 21-year prospective study of 100,000 American children. Pediatrics 2006;118(5):2173-2186. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R832141 (2007)
    R832141 (Final)
  • Abstract from PubMed
  • Abstract: Pediatrics - Abstract
    Exit
  • Journal Article Landrigan PJ, Woolf AD, Gitterman B, Lanphear B, Forman J, Karr C, Moshier EL, Godbold J, Crain E. The Ambulatory Pediatric Association fellowship in pediatric environmental health: a 5-year assessment. Environmental Health Perspectives 2007;115(10):1383-1387. R831711 (2007)
    R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Landrigan PJ, Trasande L, Swanson JM. Genetics, altruism, and the National Children’s Study. American Journal of Medical Genetics Part A 2008;146(3):294-296. R831711 (2007)
  • Abstract from PubMed
  • Full-text: Wiley Online-Full Text PDF
    Exit
  • Other: Wiley Online-Full Text HTML
    Exit
  • Journal Article Landrigan PJ, Forman J, Galvez M, Newman B, Engel SM, Chemtob C. Impact of September 11 World Trade Center disaster on children and pregnant women. Mount Sinai Journal of Medicine 2008;75(2):129-134. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Landrigan PJ, Rauh VA, Galvez MP. Environmental justice and the health of children. Mount Sinai Journal of Medicine 2010;77(2):178-187. R831711 (Final)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Landrigan P, Garg A, Droller DBJ. Assessing the effects of endocrine disruptors in the National Children's Study. Environmental Health Perspectives 2003;111(13):1678-1682. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Lee YL, Teitelbaum S, Wolff MS, Wetmur JG, Chen J. Comparing genetic ancestry and self-reported race/ethnicity in a multiethnic population in New York City. Journal of Genetics 2010;89(4):417-423. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Indian Academy of Sciences-Full Text PDF
    Exit
  • Abstract: Springer-Abstract
    Exit
  • Journal Article Liu Z, Wolff MS, Moline J. Analysis of environmental biomarkers in urine using an electrochemical detector. Journal of Chromatography B 2005;819(1):155-159. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Longnecker MP, Wolff MS, Gladen BC, Brock JW, Grandjean P, Jacobson JL, Korrick SA, Rogan WJ, Weisglas-Kuperus N, Hertz-Picciotto I, Ayotte P, Stewart P, Winneke G, Charles MJ, Jacobson SW, Dewailly E, Boersma ER, Altshul LM, Heinzow B, Pagano JJ, Jensen AA. Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environmental Health Perspectives 2003;111(1):65-70. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Magdo HS, Forman J, Graber N, Newman B, Klein K, Satlin L, Amler RW, Winston JA, Landrigan PJ. Grand rounds: nephrotoxicity in a young child exposed to uranium from contaminated well water. Environmental Health Perspectives 2007;115(8):1237-1241. R831711 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: EHP
  • Journal Article Miodovnik A, Engel SM, Zhu C, Ye X, Soorya LV, Silva MJ, Calafat AM, Wolff MS. Endocrine disruptors and childhood social impairment. NeuroToxicology 2011;32(2):261-267. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Science Direct-Full Text HTML
    Exit
  • Abstract: Science Direct-Abstract
    Exit
  • Other: Science Direct-Full Text PDF
    Exit
  • Journal Article Needleman HL, Landrigan PJ. What level of lead in blood is toxic for a child? American Journal of Public Health 2004;94(1):8. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: American Journal of Public Health-Full Text HTML
    Exit
  • Abstract: American Journal of Public Health-Abstract
    Exit
  • Other: American Journal of Public Health-Full Text PDF
    Exit
  • Journal Article Northridge J, Ramirez OF, Stingone JA, Claudio L. The role of housing type and housing quality in urban children with asthma. Journal of Urban Health 2010;87(2):211-224. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: SpringerLink-Abstract
    Exit
  • Journal Article Pirisi A. Philip Landrigan: children's health crusader. Lancet 2005;365(9467):1301. R831711 (2007)
    R831711 (Final)
  • Full-text: ScienceDirect-Full Text PDF
    Exit
  • Abstract: ScienceDirect-Abstract & Full Text HTML
    Exit
  • Other: Lancet-Full Text PDF
    Exit
  • Journal Article Pozharny Y, Lambertini L, Ma Y, Ferrara L, Litton CG, Diplas A, Jacobs AR, Chen J, Stone JL, Wetmur J, Lee M-J. Genomic loss of imprinting in first-trimester human placenta. American Journal of Obstetrics & Gynecology 2010;202(4):391.e1-391.e8. R831711 (Final)
  • Abstract from PubMed
  • Abstract: AJOG-Abstract
    Exit
  • Journal Article Salama J, Chakraborty TR, Ng L, Gore AC. Effects of polychlorinated biphenyls on estrogen receptor-β expression in the anteroventral periventricular nucleus. Environmental Health Perspectives 2003;111(10):1278-1282. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R827039 (2002)
    R827039C002 (2002)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Sarcinelli PN, Pereira AC, Mesquita SA, Oliveira-Silva JJ, Meyer A, Menezes MA, Alves SR, Mattos RC, Moreira JC, Wolff M. Dietary and reproductive determinants of plasma organochlorine levels in pregnant women in Rio de Janeiro. Environmental Research 2003;91(3):143-150. R831711 (2005)
    R831711 (2007)
  • Abstract from PubMed
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Savitz DA, Janevic TM, Engel SM, Kaufman JS, Herring AH. Ethnicity and gestational diabetes in New York City, 1995–2003. BJOG-An International Journal of Obstetrics and Gynaecology 2008;115(8):969-978. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Full-text: Wiley Online-Full Text HTML
    Exit
  • Abstract: Wiley Online-Abstract
    Exit
  • Other: Wiley Online-Full Text PDF
    Exit
  • Journal Article Sheffield PE, Galvez MP. U.S. childhood obesity and climate change: moving toward shared environmental health solutions. Environmental Justice 2009;2(4):207-214. R831711 (Final)
  • Abstract: Liebert Online-Abstract
    Exit
  • Journal Article Stingone JA, Claudio L. Disparities in the use of urgent health care services among asthmatic children. Annals of Allergy, Asthma & Immunology 2006;97(2):244-250. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Abstract: Annals of Allergy, Asthma & Immunology-Abstract
    Exit
  • Other: Science Direct - Abstract
    Exit
  • Journal Article Stingone JA, Claudio L. Asthma and enrollment in special education among urban schoolchildren. American Journal of Public Health 2006;96(9):1593-1598. R831711 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: American Journal of Public Health-Full Text HTML
    Exit
  • Abstract: American Journal of Public Health
    Exit
  • Other: American Journal of Public Health-PDF
    Exit
  • Journal Article Stingone JA, Claudio L. Disparities in use of urgent health care services among asthmatic children. Annals of Allergy, Asthma & Immunology 2006;97(2):244-250. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Full-text: Dr. Luz Claudio
    Exit
  • Abstract: Elsevier-Abstract
    Exit
  • Journal Article Stingone J, Claudio L. Disparities in allergy testing and health outcomes among urban children with asthma. Journal of Allergy and Clinical Immunology 2008;122(4):748-753. R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Full-text: Journal of Allergy and Clinical Immunology-Full Text HTML
    Exit
  • Abstract: Journal of Allergy and Clinical Immunology-Abstract
    Exit
  • Other: Journal of Allergy and Clinical Immunology-Full Text PDF
    Exit
  • Journal Article Suk WA, Ruchirawat KM, Balakrishnan K, Berger M, Carpenter D, Damstra T, Pronczuk de Garbino J, Koh D, Landrigan PJ, Makalinao I, Sly PD, Xu Y, Zheng BS. Environmental threats to children's health in Southeast Asia and the western Pacific. Environmental Health Perspectives 2003;111(10):1340-1347. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: EHP Full Text HTML
  • Abstract: EHP
  • Journal Article Teitelbaum SL, Britton JA, Calafat AM, Ye X, Silva MJ, Reidy JA, Galvez MP, Brenner BL, Wolff MS. Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States. Environmental Research 2008;106(2):257-269. R831711 (2007)
    R831711 (Final)
    R831711C001 (2007)
  • Abstract from PubMed
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Torres-Arreola L, Berkowitz G, Torres-Sanchez L, Lopez-Cervantes M, Cebrian ME, Uribe M, Lopez-Carrillo L. Preterm birth in relation to maternal organochlorine serum levels. Annals of Epidemiology 2003;13(3):158-162. R831711 (2005)
    R831711 (2007)
  • Abstract from PubMed
  • Abstract: Annals of Epidemiology-Abstract
    Exit
  • Journal Article Trasande L, Landrigan PJ. The National Children's Study: a critical national investment. Environmental Health Perspectives 2004;112(14):A789-A790. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Trasande L, Landrigan PJ, Schechter C. Public health and economic consequences of methyl mercury toxicity to the developing brain. Environmental Health Perspectives 2005;113(5):590-596. R831711 (2005)
    R831711 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: EHP HTML
  • Abstract: EHP
  • Journal Article Trasande L, Boscarino J, Graber N, Falk R, Schechter C, Galvez M, Dunkel G, Geslani J, Moline J, Kaplan-Liss E, Miller RK, Korfmacher K, Carpenter D, Forman J, Balk SJ, Laraque D, Frumkin H, Landrigan P. The environment in pediatric practice: a study of New York pediatricians' attitudes, beliefs, and practices towards children's environmental health. Journal of Urban Health 2006;83(4):760-772. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: SpringerLink
    Exit
  • Journal Article Trasande L, Schechter CB, Haynes KA, Landrigan PJ. Mental retardation and prenatal methylmercury toxicity. American Journal of Industrial Medicine 2006;49(3):153-158. R831711 (2005)
    R831711 (2007)
    R831711 (Final)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Trasande L, Schapiro ML, Falk R, Haynes KA, Behrmann A, Vohmann M, Stremski ES, Eisenberg C, Evenstad C, Anderson HA, Landrigan PJ. Pediatrician attitudes, clinical activities, and knowledge of environmental health in Wisconsin. Wisconsin Medical Journal 2006;105(2):45-49. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Wisconsin Medical Journal-Full Text PDF
    Exit
  • Journal Article Trasande L, Cronk CE, Leuthner SR, Hewitt JB, Durkin MS, McElroy JA, Anderson HA, Landrigan PJ. The National Children's Study and the children of Wisconsin. Wisconsin Medical Journal 2006;105(2):50-54. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: Wisconsin Medical Journal PDF
    Exit
  • Journal Article Trasande L, Landrigan PJ, Schechter CB, Bopp RF. Methylmercury and the developing brain. Environmental Health Perspectives 2007;115(8):A396-A397. R831711 (2007)
  • Full-text from PubMed
  • Associated PubMed link
  • Full-text: EHP HTML
  • Abstract: EHP
  • Journal Article Wallenstein S, Chen J, Wetmur JG. Comparison of statistical models for analyzing genotype, inferred haplotype, and molecular haplotype data. Molecular Genetics and Metabolism 2006;89(3):270-273. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
    R831711C003 (2007)
  • Abstract from PubMed
  • Abstract: ScienceDirect-Abstract
    Exit
  • Journal Article Wetmur JG, Kumar M, Zhang L, Palomeque C, Wallenstein S, Chen J. Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes. Nucleic Acids Research 2005;33(8):2615-2619. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Oxford Journals-Full Text HTML
    Exit
  • Abstract: Oxford Journals-Abstract
    Exit
  • Other: Oxford Journals-Full Text PDF
    Exit
  • Journal Article Wetmur JG, Chen J. Linking emulsion PCR haplotype analysis. Methods in Molecular Biology 2011;687(3):167-175. R831711 (Final)
  • Abstract from PubMed
  • Abstract: SpringerLink
    Exit
  • Journal Article Wolff MS. Half-lives of organochlorines (OCs) in humans. Archives of Environmental Contamination and Toxicology 1999;36(4):504 (Letter to the editor). R831711 (2007)
    R831711 (Final)
  • Full-text: SpringerLink-Full Text PDF
    Exit
  • Abstract: Springer-Citation
    Exit
  • Journal Article Wolff MS, Anderson HA. Correspondence re: J. M. Schildkraut et al., environmental contaminants and body fat distribution. Cancer Epidemiol. Biomark. Prev., 8:179-183, 1999. Cancer Epidemiology Biomarkers & Prevention 1999;8(10):951-952. R831711 (2007)
  • Abstract from PubMed
  • Full-text: Cancer Epidemiology, Biomarkers and Prevention-Full Text HTML
    Exit
  • Other: Cancer Epidemiology, Biomarkers and Prevention-Full Text PDF
    Exit
  • Journal Article Wolff MS, Britton JA, Wilson VP. Environmental risk factors for breast cancer among African-American women. Cancer 2003;97(1 Suppl):289-310. R831711 (2005)
    R831711 (2007)
  • Abstract from PubMed
  • Full-text: Wiley Online-Full Text HTML
    Exit
  • Journal Article Wolff MS, Deych E, Ojo F, Berkowitz GS. Predictors of organochlorines in New York City pregnant women, 1998-2001. Environmental Research 2005;97(2):170-177. R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2004)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Wolff MS, Britton JA, Russo JC. TCDD and puberty in girls. Environmental Health Perspectives 2005;113(1):A17. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Wolff MS, Teitelbaum SL, Lioy PJ, Santella RM, Wang RY, Jones RL, Caldwell KL, Sjodin A, Turner WE, Li W, Georgopoulos P, Berkowitz GS. Exposures among pregnant women near the World Trade Center site on 11 September 2001. Environmental Health Perspectives 2005;113(6):739-748. R831711 (2005)
    R831711 (2007)
    R830827 (2004)
    R830827 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Full-text: Environmental Health Perspectives-Full Text HTML
    Exit
  • Journal Article Wolff MS. Endocrine disruptors: challenges for environmental research in the 21st Century. Annals of the New York Academy of Sciences 2006;1076:228-238. R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Abstract from PubMed
  • Abstract: Wiley Online-Abstract
    Exit
  • Journal Article Wolff MS, Engel S, Berkowitz G, Teitelbaum S, Siskind J, Barr DB, Wetmur J. Prenatal pesticide and PCB exposures and birth outcomes. Pediatric Research 2007;61(2):243-250. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C002 (2007)
    R831711C003 (2006)
    R831711C003 (2007)
  • Abstract from PubMed
  • Full-text: Nature-Full Text HTML
    Exit
  • Abstract: Nature-Abstract
    Exit
  • Other: Nature-Full Text PDF
    Exit
  • Journal Article Wolff MS, Teitelbaum SL, Windham G, Pinney SM, Britton JA, Chelimo C, Godbold J, Biro F, Kushi LH, Pfeiffer CM, Calafat AM. Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls. Environmental Health Perspectives 2007;115(1):116-121. R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (Final)
    R831711C001 (2006)
    R831711C002 (2006)
    R831711C003 (2006)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Wolff MS, Britton JA, Boguski L, Hochman S, Maloney N, Serra N, Liu Z, Berkowitz G, Larson S, Forman J. Environmental exposures and puberty in inner-city girls. Environmental Research 2008;107(3):393-400. R831711 (2007)
    R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Wolff MS, Teitelbaum SL, Pinney SM, Windham G, Liao L, Biro F, Kushi LH, Erdmann C, Hiatt RA, Rybak ME, Calafat AM, Breast Cancer and Environment Research Centers. Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls. Environmental Health Perspectives 2010;118(7):1039-1046. R831711 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Journal Article Wolff, MS, Engel SM, Berkowitz GS, Ye X, Silva MJ, Zhu C, Wetmur J, Calafat AM. Prenatal phenol and phthalate exposures and birth outcomes. Environmental Health Perspectives 2008;116(8):1092-1097. R831711 (2007)
    R831711 (Final)
    R831711C003 (2007)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Supplemental Keywords:

    Biochemistry, Chemicals, childhood development, children's environmental health, Children's Health, children's vulnerablity, endocrine disrupting chemicals, endocrine disruptors, Environmental Chemistry, Environmental Exposure and Risk, environmental health, environmental management, exposure pathways, exposure studies, fast food, Health, Health Risk Assessment, human health, lipase, neurodevelopment, neurodevelopmental toxicity, obesity, paraoxonase, pesticide exposure, pesticides, phthalates, pollutants/toxics, RFA, Risk Assessment, Scientific Discipline , RFA, Health, Scientific Discipline, ENVIRONMENTAL MANAGEMENT, POLLUTANTS/TOXICS, Environmental Chemistry, Health Risk Assessment, Chemicals, Endocrine Disruptors - Environmental Exposure & Risk, endocrine disruptors, Biochemistry, Children's Health, Endocrine Disruptors - Human Health, Risk Assessment, pesticide exposure, environmental health, childhood development, endocrine disrupting chemicals, exposure studies, pesticides, phtalates, Human Health Risk Assessment, children's vulnerablity, neurodevelopmental toxicity, exposure pathways, children's environmental health

    Relevant Websites:

    http://www.mssm.edu/research/programs/childrens-environmental-health-and-disease-prevention-research-centerexit EPA

    http://www.mountsinai.org/patient-care/service-areas/children/areas-of-care/childrens-environmental-health-centerexit EPA

    Progress and Final Reports:
    Original Abstract
    2004 Progress Report
    2005 Progress Report
    2006 Progress Report
    2007 Progress Report

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R831711C001 Growing Up Healthy in East Harlem (Community-Based Participatory Research)
    R831711C002 Pesticides, Endocrine Disruptors, Childhood Growth and Development (Birth Cohort)
    R831711C003 Genetics of Phthalate and Bisphenol A Risk in Minority Populations (Individual Susceptibility)

    Top of Page

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

    Jump to main content.