• Book (1)
  • Book Chapter (30)
  • Journal Article (382)
  • Computational Toxicology and Endocrine Disruptors: Use of Systems Biology in Hazard Identification and Risk Assessment (2004):

    R831846 - Chemical Induced Changes in Gene Expression Patterns Along the HPG-axis at Different Organizational Levels Using a Small Animal Model (Japanese medaka):

  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticlePark JW, Tompsett AR, Zhang X, Newsted JL, Jones PD, Au DW, Kong R, Wu RS, Giesy JP, Hecker M. Advanced fluorescence in situ hybridization to localize and quantify gene expression in Japanese medaka (Oryzias latipes) exposed to endocrine-disrupting compounds. Environmental Toxicology and Chemistry 2009;28(9):1951-1962.  [Abstract: PubMed | Full-text: University of Saskatchewan PDF | Abstract: Wiley] R831846 (F)
    Journal ArticleTompsett AR, Park JW, Zhang X, Jones PD, Newsted JL, Au DWT, Chen EXH, Yu R, Wu RSS, Kong RYC, Giesy JP, Hecker M. In situ hybridization to detect spatial gene expression in medaka. Ecotoxicology and Environmental Safety 2009;72(4):1257-1264.  [Abstract: PubMed | Full-text: Science Direct HTML | Abstract: Mendeley | Other: Science Direct PDF] R831846 (F)
    Journal ArticleZhang X, Hecker M, Park JW, Tompsett AR, Newsted J, Nakayama K, Jones PD, Au D, Kong R, Wu RS, Giesy JP. Real-time PCR array to study effects of chemicals on the Hypothalamic-Pituitary-Gonadal axis of the Japanese medaka. Aquatic Toxicology 2008;88(3):173-182.  [Abstract: PubMed | Full-text: Science Direct HTML | Abstract: Science Direct_Abstract | Other: Science Direct PDF] R831846 (F)


    R831847 - Estrogen Elicited Gene Expression Network Elucidation in the Rat Uterus:

  • Book Chapter (1)
  • Journal Article (13)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterKwekel JC, Burgoon LD, Zacharewski TR. Comparative toxicogenomics in mechanistic and predictive toxicology. In: Brown JR, ed. Comparative Genomics: Basic and Applied Research. Boca Raton, FL: CRC Press, Taylor & Francis Group, 2008, Chapter 16, pp. 299-320.  [Abstract: CRC Press | Other: CRC Press Book URL] R831847 (2006)
    Journal ArticleKidambi S, Udpa N, Schroeder SA, Findlan R, Lee I, Chan C. Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies. Tissue Engineering 2007;13(8):2105-2117.  [Abstract: PubMed] R831847 (F)
    Journal ArticleKidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C. Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromolecular Bioscience 2007;7(3):344-353.  [Abstract: PubMed | Other: Macromolecular Bioscience PDF] R831847 (F)
    Journal ArticleKiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature, ovariectomized rat liver. Toxicological Sciences 2008;101(2)350-363.  [Abstract: PubMed | Full-text: Oxford Journals-Full Text | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R831847 (F)
    Journal ArticleKwekel JC, Burgoon LD, Burt JW, Harkema JR, Zacharewski TR. A cross-species analysis of the rodent uterotrophic program: elucidation of conserved responses and targets of estrogen signaling. Physiological Genomics 2005;23(3):327-342.  [Abstract: PubMed | Full-text: Physiological Genomics-Full Text HTML | Abstract: Physiological Genomics-Abstract | Other: Physiological Genomics-PDF] R831847 (2006)
    R831847 (F)
    Journal ArticleLi Z, Srivastava S, Yang X, Mittal S, Norton P, Resau J, Haab B, Chan C. A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells. BMC Systems Biology 2007;1:21.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: BioMed Central-Full Text | Abstract: BioMed Central-Abstract | Other: BioMed Central-PDF] R831847 (F)
    Journal ArticleLi Z, Srivastava S, Mittal S, Yang X, Sheng L, Chan C. A three stage integrative pathway search (TIPS©) framework to identify toxicity relevant genes and pathways. BMC Bioinformatics 2007;8:202.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: BioMed Central-Full Text HTML | Abstract: BioMed Central-Abstract | Other: BioMed Central-PDF] R831847 (F)
    Journal ArticleLi Z, Shaw SM, Yedwabnick MJ, Chan C. Using a state-space model with hidden variables to infer transcription factor activities. Bioinformatics 2006;22(6):747-754.  [Abstract: PubMed | Full-text: Bioinformatics-Full Text | Abstract: Bioinformatics-Abstract | Other: Bioinformatics-PDF] R831847 (F)
    Journal ArticleLi Z, Srivastava S, Findlan R, Chan C. Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity. Biotechnology Progress 2008;24(1):29-37.  [Abstract: PubMed | Full-text: Wiley Online-Full Text HTML | Abstract: Wiley Online-Abstract | Other: Wiley Online-PDF] R831847 (F)
    Journal ArticlePatil S, Melrose J, Chan C. Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. European Journal of Neuroscience 2007;26(8):2131-2141.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R831847 (F)
    Journal ArticleSrivastava S, Chan C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnology and Bioengineering 2008;99(2):399-410.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R831847 (F)
    Journal ArticleSrivastava S, Chan C. Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells:relation to mitochondrial permeability transition. Free Radical Research 2007;41(1):38-49.  [Abstract: PubMed | Abstract: Informa Healthcare-Abstract] R831847 (F)
    Journal ArticleSrivastava S, Li Z, Yang X, Yedwabnick M, Shaw S, Chan C. Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells. BMC Genomics 2007;8:364.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: BioMed Central-Full Text HTML | Abstract: BioMed Central-Abstract | Other: ] R831847 (F)
    Journal ArticleYang X, Chan C. Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2. Cell Research 2009;19(4):469-486.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Cell Research-Full text | Abstract: Cell Research-Abstract | Other: Cell Research-PDF] R831847 (F)


    R831848 - Systems Biology Modeling of Fathead Minnow Response to Endocrine Disruptors:

  • Book Chapter (1)
  • Journal Article (6)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterDenslow ND, Knoebl I, Larkin P. Approaches in proteomics and genomics for eco-toxicology. In: Moon TW, Mommsen TP, eds. Environmental Toxicology. Biochemistry and Molecular Biology of Fishes Volume 6. San Diego, CA: Elsevier, 2005, Chapter 3, pp. 85-118.  [Abstract: Elsevier-Book Description & Table of Contents] R831848 (2006)
    Journal ArticleHemming JM, Allen HJ, Thuesen KA, Turner PK, Waller WT, Lazorchak JM, Lattier D, Chow M, Denslow N, Venables B. Temporal and spatial variability in the estrogenicity of a municipal wastewater effluent. Ecotoxicology and Environmental Safety 2004;57(3):303-310.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R831848 (2006)
    Journal ArticleKnoebl I, Hemmer MJ, Denslow ND. Induction of zona radiata and vitellogenin genes in estradiol and nonylphenol exposed male sheepshead minnows (Cyprinodon variegatus). Marine Environmental Research 2004;58(2-5):547-551.  [Abstract: PubMed | Full-text: ScienceDirect - Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect - Full Text PDF] R831848 (2006)
    Journal ArticleKnoebl I, Blum JL, Hemmer MJ, Denslow ND. Temporal gene induction patterns in sheepshead minnows exposed to 17β-estradiol. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 2006;305A(9):707-719.  [Abstract: PubMed | Full-text: ResearchGate-Abstract & Full Text PDF | Abstract: Wiley-Abstract] R831848 (2006)
    Journal ArticleVilleneuve DL, Larkin P, Knoebl I, Miracle AL, Kahl MD, Jensen KM, Makynen EA, Durhan EJ, Carter BJ, Denslow ND, Ankley GT. A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis. Environmental Science & Technology 2007;41(1):321-330.  [Abstract: PubMed | Full-text: ResearchGate-Abstract & Full Text PDF | Abstract: ES&T-Abstract] R831848 (2006)
    Journal ArticleVilleneuve DL, Knoebl I, Larkin P, Miracle AL, Carter BJ, Denslow ND, Ankley GT. Altered gene expression in the brain and liver of female fathead minnows Pimephales promelas Rafinesque exposed to fadrozole. Journal of Fish Biology 2008;72(9):2281-2340.  [Full-text: University of Nebraska-Lincoln-Full Text PDF | Abstract: Wiley - Abstract] R831848 (2006)
    Journal ArticleWatanabe KH, Jensen KM, Orlando EF, Ankley GT. What is normal? A characterization of the values and variability in reproductive endpoints of the fathead minnow, Pimephales promelas. Comparative Biochemistry and Physiology C: Toxicology & Pharmacology 2007;146(3):348-356.  [Abstract: PubMed | Full-text: ScienceDirect - Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect - Full Text PDF] R831848 (2006)


    Development and Characterization of Biological Systems for Studying Low Dose Effects of Endocrine Disrupting Chemicals (2004):

    R832134 - Development of a BBPK Model for the Thyroid Axis in the Pregnant Rat and Fetus for the Dose Response Analysis of Developmental Neurotoxicity:

  • Journal Article (5)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleFisher JW, Campbell J, Muralidhara S, Bruckner JV, Ferguson D, Mumtaz M, Harmon B, Hedge JM, Crofton KM, Kim H, Almekinder TL. Effect of PCB 126 on hepatic metabolism of thyroxine and perturbations in the hypothalamic-pituitary-thyroid axis in the rat. Toxicological Sciences 2006;90(1):87-95.  [Abstract: PubMed | Full-text: Oxford Journals-Full-Text | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R832134 (2008)
    Journal ArticleMcLanahan ED, Andersen ME, Fisher JW. A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult rat: evaluation of iodide deficiency. Toxicological Sciences 2008;102(2):241-253.  [Abstract: PubMed | Full-text: Oxford Journals-Full Text HTML | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R832134 (2007)
    R832134 (2008)
    Journal ArticleMcLanahan ED, Andersen ME, Campbell Jr. JL, Fisher JW. Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH. Environmental Health Perspectives 2009;117(5):731-738.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: EHP-Full Text HTML | Other: EHP-PDF] R832134 (2008)
    Journal ArticleMcLanahan ED, Campbell JL, Ferguson DC, Harmon B, Hedge JM, Crofton KM, Mattie DR, Braverman L, Keys DA, Mumtaz M, Fisher JW. Low-dose effects of ammonium perchlorate on the hypothalamic-pituitary-thyroid axis of adult male rats pretreated with PCB126. Toxicological Sciences 2007;97(2):308-317.  [Abstract: PubMed | Full-text: Oxford Journals-Full-Text | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R832134 (2008)
    Journal ArticleTaylor MA, Swant J, Wagner JJ, Fisher JW, Ferguson DC. Lower thyroid compensatory reserve of rat pups after maternal hypothyroidism: correlation of thyroid, hepatic, and cerebrocortical biomarkers with hippocampal neurophysiology. Endocrinology 2008;149(7):3521-3530.  [Abstract: PubMed | Full-text: Endocrine Society-Full Text HTML & PDF Link] R832134 (2007)
    R832134 (2008)


    R832136 - Low Dose Effects of In Utero Exposure to Cadmium on Puberty:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleMartin MB, Reiter R, Johnson M, Shah MS, Iann MC, Singh B, Richards JK, Wang A, Stoica A. Effects of tobacco smoke condensate on estrogen receptor-alpha gene expression and activity. Endocrinology 2007;148:4676-4686 R832136 (2006)
    Journal ArticleVeselik DJ, Divekar S, Dakshanamurthy S, Storchan GB, Turner JM, Graham KL, Huang L, Stoica A, Martin MB. Activation of estrogen receptor-alpha by the anion nitrite. Cancer Research 2008;68(10):3950-3958 R832136 (2006)


    R832137 - Low-Dose Effects of Thyroid Toxicants on Neurodevelopment:

  • Book Chapter (2)
  • Journal Article (21)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterGilbert ME, Zoeller RT. Thyroid hormone—impact on the developing brain: possible mechanism of neurotoxicity. In: Harry GJ, Tilson HA, eds. Neurotoxicology. Boca Raton, FL: CRC Press, 2010, Chapter 4, pp. 79-111.  [Abstract: Informa] R832137 (F)
    Book ChapterZoeller RT. Polychlorinated biphenyls as disruptors of thyroid hormone action. In: Robertson LW, Hansen LG, eds. PCBs: Recent Advances in Environmental Toxicology and Health Effects. Lexington, KY: University Press of Kentucky, 2001, pp. 265-272.  [Full-text: UMass | Abstract: Google Books] R832137 (F)
    Journal ArticleBansal R, Zoeller RT. Polychlorinated biphenyls (Aroclor 1254) do not uniformly produce agonist actions on thyroid hormone responses in the developing rat brain. Endocrinology 2008;149(8):4001-4008.  [Full-text: Endocrinology full text HTML | Abstract: Endocrinology abstract | Other: Endocrinology PDF] R832137 (2007)
    R832137 (F)
    Journal ArticleBrent GA, Braverman LE, Zoeller RT. Thyroid health and the environment. Thyroid 2007;17(9):807-809.  [Abstract: PubMed | Abstract: Mary Ann Liebert First Page] R832137 (2007)
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    Journal ArticleCrofton KM, Zoeller RT. Mode of action: neurotoxicity induced by thyroid hormone disruption during development—hearing loss resulting from exposure to PHAHs. Critical Reviews in Toxicology 2005;35(8-9):757-769.  [Abstract: PubMed | Abstract: Informa healthcare | Other: EPA Science Inventory abstract] R832137 (F)
    Journal ArticleDegon M, Chipkin SR, Hollot CV, Zoeller RT, Chait Y. A computational model of the human thyroid. Mathematical Biosciences 2008;212(1):22-53.  [Abstract: PubMed | Full-text: | Abstract: Science Direct] R832137 (2007)
    R832137 (F)
    Journal ArticleGauger KJ, Giera S, Sharlin DS, Bansal R, Iannacone E, Zoeller RT. Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells. Environmental Health Perspectives 2007;115(11):1623-1630.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Environmental Health Perspectives full text] R832137 (2007)
    R832137 (F)
    Journal ArticleGinsberg GL, Hattis DB, Zoeller RT, Rice DC. Evaluation of the U.S. EPA/OSWER preliminary remediation goal for perchlorate in groundwater:focus on exposure to nursing infants. Environmental Health Perspectives 2007;115(3):361-369.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Environmental Health Perspectives full text | Abstract: EPA Health & Environmental Research Online abstract] R832137 (2007)
    R832137 (F)
    Journal ArticleGore AC, Heindel JJ, Zoeller RT. Endocrine disruption for endocrinologists (and others). Endocrinology 2006;147(6 Suppl):S1-S3.  [Abstract: PubMed | Full-text: Endocrinology | Other: Endocrinology PDF] R832137 (F)
    Journal ArticleJagalur M, Pal C, Learned-Miller E, Zoeller RT, Kulp D. Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering. BMC Bioinformatics 2007;8(Suppl 10):S5.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Springer HTML | Abstract: Springer | Other: Springer PDF] R832137 (2007)
    R832137 (F)
    Journal ArticleRice DC, Reeve EA, Herlihy A, Zoeller RT, Thompson WD, Markowski VP. Developmental delays and locomotor activity in the C57BL6/J mouse following neonatal exposure to the fully-brominated PBDE, decabromodiphenyl ether. Neurotoxicology and Teratology 2007;29(4):511-520.  [Abstract: PubMed | Full-text: Science Direct full text | Abstract: Science Direct | Other: Science Direct PDF] R832137 (F)
    Journal ArticleSharlin DS, Bansal R, Zoeller RT. Polychlorinated biphenyls exert selective effects on cellular composition of white matter in a manner inconsistent with thyroid hormone insufficiency. Endocrinology 2006;147(2):846-858.  [Abstract: PubMed | Full-text: Endocrinology full text HTML | Abstract: Endocrinology | Other: Endocrinology PDF] R832137 (2005)
    R832137 (F)
    FP916424 (0)
    Journal ArticleSharlin DS, Tighe D, Gilbert ME, Zoeller RT. The balance between oligodendrocyte and astrocyte production in major white matter tracts is linearly related to serum total thyroxine. Endocrinology 2008;149(5):2527-2536.  [Abstract: PubMed | Full-text: Endocrinology full text HTML | Abstract: Endocrinology | Other: Endocrinology PDF] R832137 (2007)
    R832137 (F)
    Journal ArticleSharlin DS, Gilbert ME, Taylor MA, Ferguson DC, Zoeller RT. The nature of the compensatory response to low thyroid hormone in the developing brain. Journal of Neuroendocrinology 2010;22(3):153-165.  [Abstract: PubMed | Full-text: University of Massachusetts PDF | Abstract: Wiley abstract] R832137 (F)
    Journal ArticleTan SW, Zoeller RT. Integrating basic research on thyroid hormone action into screening and testing programs for thyroid disruptors. Critical Reviews in Toxicology 2007;37(1-2):5-10.  [Abstract: PubMed | Full-text: University of Freiburg PDF | Abstract: Informa Healthcare abstract] R832137 (2007)
    R832137 (F)
    Journal ArticleWoodruff TJ, Zeise L, Axelrad DA, Guyton KZ, Janssen S, Miller M, Miller GG, Schwartz JM, Alexeeff G, Anderson H, Birnbaum L, Bois F, Cogliano VJ, Crofton K, Euling SY, Foster PMD, Germolec DR, Gray E, Hattis DB, Kyle AD, Luebke RW, Luster MI, Portier C, Rice DC, Solomon G, Vandenberg J, Zoeller RT. Meeting report:moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environmental Health Perspectives 2008;116(11):1568-1575.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: EHP | Abstract: EHP] R832137 (F)
    Journal ArticleZoeller RT. Collision of basic and applied approaches to risk assessment of thyroid toxicants. Annals of the New York Academy of Sciences 2006;1076:168-190.  [Abstract: PubMed | Abstract: Wiley abstract] R832137 (F)
    Journal ArticleZoeller RT, Tyl RW, Tan SW. Current and potential rodent screens and tests for thyroid toxicants. Critical Reviews in Toxicology 2007;37(1-2):55-95.  [Abstract: PubMed | Full-text: University of Freiburg PDF | Abstract: Informa Healthcare] R832137 (2007)
    R832137 (F)
    Journal ArticleZoeller RT. Environmental chemicals impacting the thyroid: targets and consequences. Thyroid 2007;17(9):811-817.  [Abstract: PubMed | Abstract: Liebert Online] R832137 (2007)
    R832137 (F)
    Journal ArticleZoeller RT. Environmental neuroendocrine and thyroid disruption: relevance for reproductive medicine? Fertility and Sterility 2008;89(2 Suppl):e99-e100.  [Abstract: PubMed | Full-text: Science Direct full text | Other: Science Direct PDF] R832137 (F)
    Journal ArticleZoeller RT, Tan SW, Tyl RW. General background on the hypothalamic-pituitary-thyroid (HPT) axis. Critical Reviews in Toxicology 2007;37(1-2):11-53.  [Abstract: PubMed | Full-text: University of Freiburg PDF | Abstract: Informa Healthcare abstract] R832137 (2007)
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    Journal ArticleZoeller RT, Tan SW. Implications of research on assays to characterize thyroid toxicants. Critical Reviews in Toxicology 2007;37(1-2):195-210.  [Abstract: PubMed | Full-text: University of Freiburg PDF | Abstract: Informa Healthcare] R832137 (2007)
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    Journal ArticleZoeller RT, Crofton KM. Mode of action: developmental thyroid hormone insufficiency--neurological abnormalities resulting from exposure to propylthiouracil. Critical Reviews in Toxicology 2005;35(8-9):771-781.  [Abstract: PubMed | Full-text: University of Freiburg PDF | Abstract: Informa Healthcare abstract] R832137 (F)


    Development of High-Throughput Screening Approaches for Prioritizing Chemicals for the Endocrine Disruptors Screening Program (2003):

    R831299 - Using a Sensitive Japanese Medaka (Oryzias latipes) Fish Model for Endocrine Disruptors Screening:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleLeon A, Teh SJ, Hall LC, Teh FC. Androgen disruption of early development in Qurt strain medaka (Oryzias latipes). Aquatic Toxicology 2007;82(3):195-203.  [Abstract: PubMed | Full-text: Science Direct Full Text | Other: Science Direct Full Text (PDF)] R831299 (2006)
    R831299 (2007)
    Journal ArticleLeon A, Wu P-S, Hall LC, Johnson ML, Teh SJ. Global gene expression profiling of androgen disruption in Qurt strain medaka. Environmental Science & Technology 2008;42(3):962-969.  [Abstract: PubMed] R831299 (2006)


    R831300 - Mechanistic Approach to Screening Chemicals and Mixtures for Endocrine Activity Using an Invertebrate Model:

  • Journal Article (9)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA. A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. Molecular and Cellular Endocrinology 2006;247(1-2):91-102.  [Abstract: PubMed | Full-text: ScienceDirect-FullText HTML | Other: ScienceDirect-PDF] R829358 (F)
    R831300 (2005)
    R831300 (2006)
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    R832739 (2008)
    Journal ArticleLeBlanc GA. Crustacean endocrine toxicology: a review. Ecotoxicology 2007;16(1):61-81.  [Abstract: PubMed | Abstract: Springer-Abstract] R826129 (F)
    R831300 (F)
    R832739 (2007)
    R832739 (F)
    Journal ArticleMu XY, LeBlanc GA. Cross communication between signaling pathways: Juvenoid hormones modulate ecdysteroid activity in a crustacean. Journal of Experimental Zoology Part A-Comparative Experimental Biology 2004;301A(10):793-801. R826129 (F)
    R829358 (2004)
    R829358 (F)
    R831300 (2004)
    Journal ArticleMu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. Environmental Toxicology and Chemistry 2005;24(1):146-152.  [Abstract: PubMed | Full-text: ResearchGate-PDF | Abstract: Wiley-Abstract] R829358 (2004)
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    Journal ArticleOlmstead AW, LeBlanc GA. The environmental-endocrine basis of gynandromorphism (intersex) in a crustacean. International Journal of Biological Sciences 2006;3(2):77-84.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: International Journal of Biological Sciences-Full Text HTML | Abstract: International Journal of Biological Sciences-Abstract | Other: International Journal of Biological Sciences-PDF] R831300 (F)
    R832739 (2006)
    R832739 (2007)
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    Journal ArticleRider CV, LeBlanc GA. Atrazine stimulates hemoglobin accumulation in Daphnia magna: is it hormonal or hypoxic? Toxicological Sciences 2006;93(2):443-449.  [Abstract: PubMed | Full-text: Oxford Journals-Full Text HTML | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R829358 (F)
    R831300 (F)
    Journal ArticleRider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA. Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. Journal of Experimental Biology 2005;208(Pt 1):15-23.  [Abstract: PubMed | Full-text: JEB-Full Text HTML | Abstract: JEB-Abstract | Other: JEB-PDF] R829358 (F)
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    R831300 (2006)
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    R832739 (2008)
    Journal ArticleWang HY, Olmstead AW, Li H, LeBlanc GA. The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna. Aquatic Toxicology 2005;74(3):193-204.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R831300 (2005)
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    R832739 (2008)
    Journal ArticleWang YH, Wang G, LeBlanc GA. Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna. General and Comparative Endocrinology 2007;150(2):309-318.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R831300 (2006)
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    R831301 - A High Throughput Zebrafish Embryo Gene Expression System for Screening Endocrine Disrupting Chemicals:

  • Journal Article (7)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBurnett KG, Bain LJ, Baldwin WS, Callard GV, Cohen S, Di Giulio RT, Evans DH, Gomez-Chiarri M, Hahn ME, Hoover CA, Karchner SI, Katoh F, MacLatchy DL, Marshall WS, Meyer JN, Nacci DE, Oleksiak MF, Rees BB, Singer TD, Stegeman JJ, Towle DW, Van Veld PA, Vogelbein WK, Whitehead A, Winn RN, Crawford DL. Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 2007;2(4):257-286.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Science Direct HTML | Abstract: Science Direct | Other: Science Direct PDF] R831301 (F)
    Journal ArticleGreytak SR, Callard GV. Cloning of three estrogen receptors (ER) from killifish (Fundulus heteroclitus): differences in populations from polluted and reference environments. General and Comparative Endocrinology 2007;150(1):174-188.  [Abstract: PubMed | Full-text: Science Direct HTML | Abstract: Science Direct | Other: Science Direct PDF] R831301 (2006)
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    Journal ArticleGreytak SR, Tarrant AM, Nacci D, Hahn ME, Callard GV. Estrogen responses in killifish (Fundulus heteroclitus) from polluted and unpolluted environments are site-and gene-specific. Aquatic Toxicology 2010;99(2):291-299.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct PDF] R831301 (F)
    Journal ArticleGreytak SR, Champlin D, Callard GV. Isolation and characterization of two cytochrome P450 aromatase forms in killifish (Fundulus heteroclitus): differential expression in fish from polluted and unpolluted environments. Aquatic Toxicology 2005;71(4):371-389.  [Abstract: PubMed | Full-text: Science Direct HTML | Abstract: Science Direct Abstract | Other: Science Direct PDF] R831301 (2006)
    R831301 (F)
    Journal ArticleMcCurley AT, Callard GV. Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment. BMC Molecular Biology 2008;9:102.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Biomed Central HTML | Abstract: Biomed Central | Other: Biomed Central PDF] R831301 (F)
    Journal ArticleSawyer SJ, Gerstner KA, Callard GV. Real-time PCR analysis of cytochrome P450 aromatase expression in zebrafish: gene specific tissue distribution, sex differences, developmental programming, and estrogen regulation. General and Comparative Endocrinology 2006;147(2):108-117.  [Abstract: PubMed | Full-text: Science Direct HTML | Abstract: Science Direct Abstract | Other: Science Direct PDF] R831301 (2004)
    R831301 (2006)
    R831301 (F)
    Journal ArticleTarrant AM, Greytak SR, Callard GV, Hahn ME. Estrogen receptor-related receptors in the killifish Fundulus heteroclitus: diversity, expression, and estrogen responsiveness. Journal of Molecular and Cellular Endocrinology 2006;37(1):105-120.  [Abstract: PubMed | Full-text: JME Full Text HTML | Abstract: JME | Other: JME PDF] R831301 (2006)
    R831301 (F)


    R831302 - Development and Application of a Bioluminescent Yeast-Reporter System for Screening Chemicals for Estrogenic and Androgenic Effects:

  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleEldridge ML, Sanseverino J, Layton AC, Easter JP, Schultz TW, Sayler GS. Saccharomyces cerevisiae BLYAS, a new bioluminescent bioreporter for detection of androgenic compounds. Applied and Environmental Microbiology 2007;73(19):6012-6018.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R831302 (F)
    Journal ArticleHaggerty JL, Reid RJ, Freeman GK, Starfield BH, Adair CE, McKendry R. Continuity of care: a multidisciplinary review. British Medical Journal 2003;327(7425):1219-1221 R831302 (F)
    Journal ArticleSanseverino J, Gupta RK, Layton AC, Patterson SS, Ripp SA, Saidak L, Simpson ML, Schultz TW, Sayler GS. Use of Saccharomyces cerevisiae BLYES expressing bacterial bioluminescence for rapid, sensitive detection of estrogenic compounds. Applied and Environmental Microbiology 2005;71(8):4455-4460.  [Abstract: PubMed | Full-text: American Society for Microbiology Full Text | Other: American Society for Microbiology PDF] R831302 (2004)
    R831302 (2005)
    R831302 (2006)
    R831302 (F)


    Endocrine Disruptors (1996):

    R825294 - Critical Stages in Avian Development: Estrogen Hazards to Altricial and Precocial Birds:

  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleMillam JR, Craig-Veit CB, Quaglino AE, Erichsen AL, Famula TR, Fry DM. Post-hatch oral estrogen exposure impairs adult reproductive performance of Zebra Finch in a sex-specific manner. Hormones and Behavior 2001;40(4):542-549. R825294 (F)
    Journal ArticleQuaglino AE, Craig-Veit CB, Viant MR, Erichsen AL, Fry DM, Millam JR. Oral estrogen masculinizes female Zebra Finch song system. Hormones and Behavior 2002;41(2):236-241. R825294 (F)
    Journal ArticleViant MR, Millam JR, Delany ME, Fry DM. Regulation of brain-derived neurotrophic factor messenger RNA levels in avian hypothalamic slice cultures. Neuroscience 2000;99(2):373-380. R825294 (F)


    R825295 - Methoxychlor and Environmental "Estrogen" Receptors in ER-Minus Mice:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal Article Das SK, Taylor JA, Korach KS, Paria BC, Dey SK, Lubahn DB. Estrogenic responses in estrogen receptor-α deficient mice reveal a distinct estrogen signaling pathway. Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12786-12791 R825295 (1998)
    Journal Article Ghosh D, Taylor JA, Green JA, Lubahn DB. Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (Non-ER)alpha and Non-ER beta mechanism. Endocrinology 1999;140(8):3526-3533 R825295 (F)


    R825296 - Biochemical and Reproductive Effects of Gestational/Lactational Exposure to PCB's with Respect to Endogenous Sex Steroids and the Proestrogen, Methoxychlor:

  • Journal Article (1)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleCarr RL, Richardson JR, Guarisco JA, Kachroo A, Chambers JE, Couch TA, Durunna GC, Meek EC. Effects of PCB exposure on the toxic impact of organophosphorus insecticides. Toxicological Sciences 2002;67(2):311-321 R825296 (0)


    R825298 - An in vivo Model for Detection of Reproductive Effects of Endocrine Disruptors:

  • Journal Article (6)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleCooke JB, Hinton DE. Promotion by 17 beta-estradiol and beta-hexachlorocyclohexane of hepatocellular tumors in medaka, Oryzias latipes. Aquatic Toxicology 1999;45(2-3):127-145. R825298 (F)
    Journal ArticleTeh SJ, Hinton DE. Gender-specific growth and hepatic neoplasia in medaka (Oryzias latipes). Aquatic Toxicology 1998;41(1-2):141-159.  [Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R825298 (F)
    R825433 (F)
    Journal ArticleKoger CS, Teh SJ, Hinton DE. Determining the sensitive developmental stages of intersex induction in medaka (Oryzias latipes) exposed to 17β-estradiol or testosterone. Marine Environmental Research 2000;50(1-5):201-206.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text PDF | Abstract: ScienceDirect-Abstract & Full Text HTML | Other: ResearchGate-Abstract & Full Text PDF] R825298 (F)
    R825433 (F)
    Journal ArticleKoger CS, Teh SJ, Hinton DE. Variations of light and temperature regimes and resulting effects on reproductive parameters in medaka (Oryzias latipes). Biology of Reproduction 1999;61(5):1287-1293.  [Abstract: PubMed | Full-text: Biology of Reproduction-Full Text HTML | Abstract: Biology of Reproduction-Abstract | Other: Biology of Reproduction-Full Text PDF] R825298 (F)
    R825433 (F)
    Journal ArticleKullman SW, Hamm JT, Hinton DE. Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes). Archives of Biochemistry and Biophysics 2000;380(1):29-38.  [Abstract: PubMed | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-PDF] R825298 (F)
    R834514 (2011)
    Journal ArticleKullman SW, Hinton DE. Identification characterization and ontogeny of a second cytochrome P450 3A gene from the fresh water teleost medaka (Oryzias latipes). Molecular Reproduction and Development 2001;58(2):149-158. R825298 (F)


    R825300 - The Michigan PBB Cohort 20 Years: Endocrine Disruption?:

  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBlanck HM, Marcus M, Tolbert PE, Rubin C, Henderson AK, Hertzberg VS, Zhang RH, Cameron L. Age at menarche and tanner stage in girls exposed in utero and postnatally to polybrominated biphenyl. Epidemiology 2000;11(6):641-647. R825300 (2002)
    R825300 (F)
    Journal ArticleBlanck HM, Marcus M, Hertzberg V, Tolbert PE, Rubin C, Henderson AK, Zhang RH. Determinants of polybrominated biphenyl serum decay among women in the Michigan PBB cohort. Environmental Health Perspectives 2000;108(2):147-152. R825300 (2002)
    R825300 (F)
    Journal ArticleBlanck HM, Marcus M, Rubin C, Tolbert PE, Hertzberg VS, Henderson AK, Zhang RH. Growth in girls exposed in utero and postnatally to polybrominated biphenyls and polychlorinated biphenyls. Epidemiology 2002;13(2):205-210. R825300 (2002)
    R825300 (F)
    Journal ArticleBlanck HM, Marcus M, Tolbert PE, Schuch C, Rubin C, Henderson AK, Zhang RH, Hertzberg VS. Time to menopause in relation to PBBs, PCBs, and smoking. Maturitas 2004;49(2):97-106. R825300 (2002)
    R825300 (F)
    Journal ArticleKaiser R, Marcus M, Blanck HM, Naughton M, Zhang RH, Henderson AK, Tolbert PE, Rubin CH, Hertzberg VS. Polybrominated biphenyl exposure and benign breast disease in a cohort of US women. Annals of Epidemiology 2003;13(1):16-23. R825300 (2002)
    R825300 (F)
    Journal Article Marcus M, Cheslack-Postava K, Tolbert PE, Hertzberg V, Small C, Blanck HM, Henderson A, Rubin C, Thomas A. Breast-feeding and PBBs: Response to Rogan and Weil. Environmental Health Perspectives 2002;110(9):A504-A504 R825300 (F)
    Journal ArticleRogan WJ, Weil WB. Duration of breast-feeding and PBBs. Environmental Health Perspectives 2002;110(9):A503-A504. R825300 (2002)
    R825300 (F)
    Journal ArticleThomas AR, Marcus M, Zhang RH, Blanck HM, Tolbert PE, Hertzberg V, Henderson AK, Rubin C. Breast-feeding among women exposed to polybrominated biphenyls in Michigan. Environmental Health Perspectives 2001;109(11):1133-1137. R825300 (2002)
    R825300 (F)


    R825434 - Xenoestrogen Effects During Premeiotic Stages of Spermatogenesis Development of an InVitro Test System and Molecular Markers of Action:

  • Book Chapter (4)
  • Journal Article (5)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterCallard GV, McClusky LM, Betka M. Apoptosis as a normal mechanism of growth control and target of toxicant actions during spermatogenesis: insights using the shark testis model. In: Le Gal Y, Halvorson LGA, eds. New Developments in Marine Biotechnology. New York, NY: Plenum Press, 1998, pp. 125-128.  [Abstract: Springer - Abstract] R825434 (F)
    Book ChapterCallard GV, Callard IP. Spermatogenesis in nonmammals. In: Knobil E, Neill J, eds. Encyclopedia of Reproduction. San Diego, CA: Academic Press, 1999, pp. 563-570. R825434 (F)
    Book ChapterEngel KB, Callard GV. Endocrinology of Leydig cells in nonmammalian vertebrates. In: Payne AH, Hardy MP, eds. The Leydig Cell in Health and Disease. Totowa, NJ: Humana Press, 2007, pp. 207-224.  [Abstract: Springer - Abstract] R825434 (F)
    Book ChapterEngel KB, Callard GV, The testis and spermatogenesis. In Hamlett WC, ed. Reproductive Biology and Phylogeny of Chondrichthyes: Sharks, Batoids, and Chimaeras. Enfield, NH: Science Publishers, 2005, pp. 171-200. R825434 (F)
    Journal ArticleBetka M, Welenc A, Franks DG, Hahn ME, Callard GV. Characterization of two aryl hydrocarbon receptor (AHR) mRNA forms in Squalus acanthias and stage-dependent expression during spermatogenesis. The Bulletin, Mount Desert Island Biological Laboratory 2000;39:110-112. R825434 (F)
    Journal ArticleBetka M, Callard GV. Stage-dependent accumulation of cadmium and induction of metallothionein-like binding activity in the testis of the dogfish shark, Squalus acanthias. Biology of Reproduction 1999;60(1):14-22.  [Abstract: PubMed | Full-text: Biology of Reproduction - Full text HTML | Abstract: Biology of Reproduction - Abstract | Other: Biology of Reproduction - PDF] R825434 (F)
    Journal ArticleMcClusky LM. Stage and season effects on cell cycle and apoptotic activities of germ cells and Sertoli cells during spermatogenesis in the spiny dogfish (Squalus acanthias). Reproduction 2005;129(1):89-102.  [Abstract: PubMed | Full-text: Reproduction-Full-Text | Abstract: Reproduction-Abstract | Other: Reproduction-PDF] R825434 (F)
    Journal ArticleMcClusky LM. Stage-dependency of apoptosis and the blood-testis barrier in the dogfish shark (Squalus acanthias): cadmium-induced changes as assessed by vital fluorescence techniques. Cell and Tissue Research 2006;325(3):541-553.  [Abstract: PubMed | Abstract: Springer-Abstract] R825434 (F)
    Journal ArticleWang C, Callard GV. Polymerase chain reaction (PCR)-differential display identifies a subset of stage-dependent and cadmium-regulated genes during spermatogenesis in Squalus acanthias. The Bulletin, Mount Desert Island Biological Laboratory 2001;40:96-98.  [Abstract: The Bulletin] R825434 (F)


    Endocrine Disruptors (1997):

    R826125 - Reproductive and endocrine effects of o,p'-DDT, an environmental estrogen, and p,p'-DDE, an antiandrogen in male and female Atlantic croaker during critical periods of their reproductive life history cycles:

  • Journal Article (5)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleHawkins MB, Thornton JW, Crews D, Skipper JK, Dotte A, Thomas P. Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in vertebrates (submitted for publication). R826125 (2001)
    Journal ArticleLarsson DG, Sperry TS, Thomas P. Regulation of androgen receptors in Atlantic croaker brains by testosterone and estradiol. General and Comparative Endocrinology 2002;128(3):224-230 R826125 (2001)
    Journal ArticleLoomis AK, Thomas P. Binding characteristics of estrogen receptor (ER) in Atlantic croaker (Micropogonias undulatus) testes: Different affinity for estrogens and xenobiotics from that of hepatic ER. Biology of Reproduction 1999;61(1):51-60. R826125 (2001)
    Journal ArticleLoomis AK, Thomas P. Effects of estrogens and xenoestrogens on androgen production by Atlantic croaker testes in vitro: Evidence for a nongenomic action mediated by an estrogen membrane receptor. Biology of Reproduction 2000;62(4):995-1004. R826125 (1999)
    R826125 (2001)
    Journal ArticleThomas P. Chemical interference with genomic and nongenomic actions of steroids in fishes: role of receptor binding. Marine Environmental Research 2000;50(1-5):127-134. R826125 (1999)
    R826125 (2001)


    R826128 - The Mechanisms and Effects of Endocrine Disruption on Infertility in the Bonnethead Shark on Florida's Gulf Coast:

  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBethea DM, Hale L, Carlson JK, Cortes E, Manire CA, Gelsleichter J. Geographic and ontogenetic variation in the diet and daily ration of the bonnethead shark, Sphyrna tiburo, from the eastern Gulf of Mexico. Marine Biology 2007;152(5):1009-1020 R826128 (F)
    Journal ArticleChapman DD, Prodohl PA, Gelsleichter J, Manire CA, Shivji MS. Predominance of genetic monogamy by females in a hammerhead shark, Sphyrna tiburo: implications for shark conservation. Molecular Ecology 2004;13(7):1965-1974 R826128 (F)
    Journal ArticleGelsleichter J, Manire CA, Szabo NJ, Cortes E, Carlson J, Lombardi-Carlson L. Organochlorine concentrations in bonnethead sharks (Sphyrna tiburo) from four Florida estuaries. Archives of Environmental Contamination and Toxicology 2005;48(4):474-483 R826128 (F)
    Journal ArticleGelsleichter J, Steinetz BG, Manire CA, Ange C. Serum relaxin concentrations and reproduction in male bonnethead sharks, Sphyrna tiburo. General and Comparative Endocrinology 2003;132(1):27-34. R826128 (F)
    Journal ArticleManire CA, Rasmussen LE, Gelsleichter J, Hess DL. Maternal serum and yolk hormone concentrations in the placental viviparous bonnethead shark, Sphyrna tiburo. General and Comparative Endocrinology 2004;136(2):241-247 R826128 (F)
    Journal ArticleMccomb DM, Gelsleichter J, Manire CA, Brinn R, Brown CL. Comparative thyroid hormone concentration in maternal serum and yolk of the bonnethead shark (Sphyrna tiburo) from two sites along the coast of Florida. General and Comparative Endocrinology 2005;144(2):167-173 R826128 (F)
    Journal ArticleNichols S, Gelsleichter J, Manire CA, Cailliet GM. Calcitonin-like immunoreactivity in serum and tissues of the bonnethead shark, Sphyrna tiburo. Journal of Experimental Zoology Part A-Comparative Experimental Biology 2003;298A(2):150-161. R826128 (F)
    Journal ArticleSong J, Kinney KA. Effect of vapor-phase bioreactor operation on biomass accumulation, distribution, and activity: linking biofilm properties to bioreactor performance. Biotechnology and Bioengineering 2000;68(5):508-516.  [Abstract: PubMed | Abstract: Wiley - Abstract] R826128 (F)
    R826168 (1999)
    R826168 (F)


    R826129 - Metabolic Androgenization of Invertebrates by Endocrine-Disrupting Chemicals:

  • Book Chapter (11)
  • Journal Article (26)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book Chapter Andren AW, Bober TW. Silver in the Environment: Transport, Fate, and Effects. SETAC, . 2002: R826129 (F)
    Book ChapterBell R, Bielmayer G, Galvez F, Hogstrand C, LeBlanc G, Lee, B-G, Luoma S, Purcell T, Santore R, Santschi P, Shaw J. In: SETAC Press: Transport, Fate and Effects of Silver in the Environment. R826129 (2000)
    Book Chapter DeFur P, Crane M, Ingersoll C, Tattersfield L. Endocrine Disruption in Invertebrates: Endocrinology, Testing, and Assessment. SETAC, . 1999: R826129 (F)
    Book ChapterDeFur PL, Crane M, Tattersfield LJ, Ingersoll CG, Stahl RG, Matthiessen P, DeFur PL, Crane M, Ingersoll CG, Tattersfield LJ. Executive Summary on EDIETA Workshop. SETAC Press, Pensacola, FL. 1999;1-6 R826129 (F)
    Book ChapterdeFur PL, Crane M, Tattersfield LJ, Ingersoll CG, Stahl RG Jr, Matthiessen P, et al. Workshop on Endocrine Disruption in Invertebrates: Endocrinology, Testing, and Assessment (EDIETA): Executive Summary. Endocrine Disruption in Invertebrates: Endocrinology, Testing, and Assessment. DeFur P, Crane M, Ingersoll C, Tattersfield L, eds. SETAC, Pensacola, FL, 1999:1-6. R826129 (1999)
    Book ChapterHenshel DS, Harrass MC, Black MC. Environmental Toxicology and Risk Assessment: Standardization of Biomarkers for Endocrine Disruption and Environmental Assessment. 8th Volume. 1999. R826129 (F)
    Book ChapterLeBlanc GA, Dauterman WC. Conjugation and elimination of toxicants. In: Hodgson E, Smart RC, eds. Introduction to Biochemical Toxicology. 2001, Ch. 6, pp. 115-136. R826129 (2000)
    R826129 (F)
    R829358 (F)
    Book ChapterLeBlanc GA. Immunochemical techniques in toxicology. In: Hodgson E, Smart RC, eds. Biochemical Toxicology. East Norwalk, CT: Appleton & Lange. In press. Ch. 3, pp. 33-50. R826129 (2000)
    R826129 (F)
    Book ChapterLeBlanc GA. Screening approaches for the evaluation of endocrine disruption in invertebrates. In: Environmental Toxicology and Risk Assessment: Standardization of Biomarkers for Endocrine Disruption and Environmental Assessment. Henshel DS, Black MC, Harrass MC, eds. STP 1364. American Society of Testing and Materials, West Conshohocken, PA, 1999;8:3-23. R826129 (1999)
    R826129 (F)
    Book ChapterLeBlanc GA. Steroid hormone-regulated processes in invertebrates and their susceptibility to environmental endocrine disruption. In: Guillette Jr L, Crain DA, eds. Environmental Endocrine Disrupters: An Evolutionary Perspective. London: Taylor and Francis Publishers, 2000, pp. 126-154. R826129 (2000)
    R826129 (F)
    Book ChapterLuoma SN, Hogstrand C, Bell RA, Bielmyer GK, Galvez F, LeBlanc GA, Byeong-Gweon L, Purcell TW, Santore RC, Santschi PH, Shaw JR, Andren AW, Bober TW. Biological processes. SETAC Press, Pensacola, FL. 2002;65-96 R826129 (F)
    Journal ArticleAngus RA, McNatt HB, Howell WM, Peoples SD. Gonopodium development in normal male and 11-ketotestosterone-treated female mosquitofish (Gambusia affinis): a quantitative study using computer image analysis. General and Comparative Endocrinology 2001;123(2):222-234.  [Abstract: PubMed | Abstract: ScienceDirect] R826130 (1999)
    R826129 (F)
    Journal ArticleGooding MP, LeBlanc GA. Biotransformation and disposition of testosterone in the eastern mud snail Ilyanassa obsoleta. General and Comparative Endocrinology 2001;122(2):172-180. R826129 (2000)
    R826129 (F)
    Journal ArticleGooding MP, LeBlanc GA. Seasonal variation in the regulation of testosterone levels in the eastern mud snail (Ilyanassa obsoleta). Invertebrate Biology 2004;123(3):237-243 R826129 (F)
    Journal ArticleGooding MP, Wilson VS, Folmar LC, Marcovich DT, LeBlanc GA. The biocide tributyltin reduces the accumulation of testosterone as fatty acid esters in the mud snail (Ilyanassa obsoleta). Environmental Health Perspectives 2003;111(4):426-430. R826129 (F)
    Journal ArticleGunderson MP, LeBlanc GA, Guillette LJ. Alterations in sexually dimorphic biotransformation of testosterone in juvenile American alligators (Alligator mississippiensis) from contaminated lakes. Environmental Health Perspectives 2001;109(12):1257-1264. R826129 (2000)
    R826129 (2001)
    R826129 (F)
    Journal ArticleKast-Hutcheson K, Rider CV, LeBlanc GA. The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna. Environmental Toxicology and Chemistry 2001, Volume: 20, Number: 3 (MAR), Page: 502-509. R826129 (2000)
    R826129 (F)
    Journal Article Korte JJ, Kahl MD, Jensen KM, Pasha MS, Parks LG, Leblanc GA, Ankley GT. Fathead minnow vitellogenin: Complementary DNA sequence and messenger RNA and protein expression after 17 beta-estradiol treatment. Environmental Toxicology and Chemistry 2000;19(4):972-981 R826129 (2000)
    R826129 (F)
    Journal ArticleLeBlanc GA, McLachlan JB. Changes in the metabolic elimination profile of testosterone following exposure of the crustacean Daphnia magna to tributyltin. Ecotoxicology and Environmental Safety 2000;45(3):296-303. R826129 (2000)
    R826129 (F)
    Journal ArticleLeBlanc GA. Crustacean endocrine toxicology: a review. Ecotoxicology 2007;16(1):61-81.  [Abstract: PubMed | Abstract: Springer-Abstract] R826129 (F)
    R831300 (F)
    R832739 (2007)
    R832739 (F)
    Journal ArticleLeBlanc GA, Mu XY, Rider CV. Embryotoxicity of the alkylphenol degradation product 4-nonylphenol to the crustacean Daphnia magna. Environmental Health Perspectives 2000;108(12):1133-1138. R826129 (2000)
    R826129 (F)
    Journal ArticleLeBlanc GA, McLachlan JB. Molt-independent growth inhibition of Daphnia magna by an anti-androgen. Environmental Toxicology and Chemistry 1999;18:1450?1455. R826129 (1999)
    R826129 (F)
    Journal ArticleMu XY, LeBlanc GA. Cross communication between signaling pathways: Juvenoid hormones modulate ecdysteroid activity in a crustacean. Journal of Experimental Zoology Part A-Comparative Experimental Biology 2004;301A(10):793-801. R826129 (F)
    R829358 (2004)
    R829358 (F)
    R831300 (2004)
    Journal ArticleMu XY, LeBlanc GA. Environmental antiecdysteroids alter embryo development in the crustacean Daphnia magna. ournal of Experimental Zoology 2002;292(3):287-292. R826129 (2001)
    R826129 (F)
    R829358 (2003)
    R826120 (F)
    Journal ArticleMu XY, LeBlanc GA. Synergistic interaction of endocrine - disrupting chemicals: Model development using an ecdysone receptor antagonist and a hormone synthesis inhibitor. Environmental Toxicology and Chemistry 2004;23(4):1085-1091. R826129 (F)
    R829358 (2003)
    R829358 (2004)
    R829358 (F)
    Journal ArticleMu XY, LeBlanc GA. Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity. General and Comparative Endocrinology 2002;129(2):127-133. R826129 (F)
    R829358 (2003)
    Journal ArticleOlmstead AW, LeBlanc GA. Effects of endocrine-active chemicals on the development of sex characteristics of Daphnia magna. Environmental Toxicology and Chemistry 2000;19(8):2107-2113. R826129 (2000)
    R826129 (F)
    Journal Article Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environmental Health Perspectives 2003;111(7):919-924. R826129 (F)
    R829358 (2003)
    Journal Article Olmstead AW, LeBlanc GA. Juvenoid hormone methyl farnesoate is a sex determinant in the crustacean Daphnia magna. Journal of Experimental Zoology 2002;293(7):736-739. R826129 (F)
    R829358 (2003)
    Journal ArticleOlmstead AW, LeBlanc GA. Low exposure concentration effects of methoprene on endocrine-regulated processes in the crustacean Daphnia magna. Toxicological Sciences 2001;62(2):268-273. R826129 (2001)
    R826129 (F)
    Journal ArticleOlmstead AW, LeBlanc GA. Temporal and quantitative changes in sexual reproductive cycling of the cladoceran Daphnia magna by a juvenile hormone analog. Journal of Experimental Zoology 2001;290(2):148-155. R826129 (2000)
    R826129 (F)
    Journal ArticlePutz O, Schwartz CB, Kim S, LeBlanc GA, Cooper RL, Prins GS. Neonatal low- and high-dose exposure to estradiol benzoate in the male rat: I. Effects on the prostate gland. Biology of Reproduction 2001;65(5):1496-1505. R826299 (1999)
    R826129 (2001)
    R826129 (F)
    Journal ArticlePutz O, Schwartz CB, LeBlanc GA, Cooper GL, Prins GS. Neonatal low- and high-dose exposure to estradiol benzoate in the male rat: II. Effects on male puberty and the reproductive tract. Biology of Reproduction 2001;65(5):1506-1517. R826129 (2001)
    Journal ArticleWilson VS, LeBlanc GA. Petroleum pollution. In: Hodgson E, ed. Reviews in Toxicology. Volume 3. Environmental Toxicology. Amsterdam: IOS Press, 2000, pp. 77-112. R826129 (2000)
    R826129 (F)
    Journal ArticleWilson VS, LeBlanc GA. The contribution of hepatic inactivation of testosterone to the lowering of serum testosterone levels by ketoconazole. Toxicological Sciences 2000;54(1):128-137. R826129 (2000)
    R826129 (F)
    Journal ArticleWolf CJ, LeBlanc GA, Ostby JS, Gray LE. Characterization of the period of sensitivity of fetal male sexual development to vinclozolin. Toxicological Sciences 2000;55(1):152-161. R826129 (2000)
    R826129 (F)
    Journal ArticleWolf CJ, Hotchkiss A, Ostby JS, LeBlanc GA, Gray LE. Effects of prenatal testosterone propionate on the sexual development of male and female rats: A dose-response study. Toxicological Sciences 2002;65(1):71-86. R826129 (2001)
    R826129 (F)
    R829358 (2003)


    R826130 - A Short-Term In Vivo Screening System For Endocrine Disruptors Utilizing Mosquitofishes (Gambusia affinis and G. holbrooki):

  • Book Chapter (1)
  • Journal Article (12)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterStanko JP, Angus RA. Paper manufacture and its impact on the aquatic environment. In: Ware GW, ed. Reviews of Environmental Contamination and Toxicology. New York, NY: Springer, 2006, Volume 185, pp. 67-92.  [Abstract: Springerlink] R826130 (1999)
    Journal ArticleMeleth AD, Angus RA. Age as a variable in the induced masculinization of female mosquitofish Gambusia affinis. Journal of the Alabama Academy of Science 2000;72.  [Abstract: The Free Library] R826130 (1999)
    Journal ArticleAngus RA, Stanko J, Jenkins RL, Watson RD. Effects of 17α-ethynylestradiol on sexual development of male Western mosquitofish (Gambusia affinis). Comparative Biochemistry and Physiology C: Toxicology & Pharmacology 2005;140(3-4):330-339.  [Abstract: PubMed | Full-text: ScienceDirect - Full Text HTML | Abstract: ScienceDirect | Other: ScienceDirect - Full Text PDF] R826130 (1999)
    Journal ArticleAngus RA, Weaver SA, Grizzle JM, Watson RD. Reproductive characteristics of male mosquitofish (Gambusia affinis) inhabiting a small southeastern U.S. river receiving treated domestic sewage effluent. Environmental Toxicology and Chemistry 2002;21(7):1404-1409.  [Abstract: PubMed | Abstract: Wiley] R826130 (1999)
    Journal ArticleAngus RA, McNatt HB, Howell WM, Peoples SD. Gonopodium development in normal male and 11-ketotestosterone-treated female mosquitofish (Gambusia affinis): a quantitative study using computer image analysis. General and Comparative Endocrinology 2001;123(2):222-234.  [Abstract: PubMed | Abstract: ScienceDirect] R826130 (1999)
    R826129 (F)
    Journal ArticleEstes ECJ, Katholi CR, Angus RA. Elevated fluctuating asymmetry in eastern mosquitofish (Gambusia holbrooki) from a river receiving paper mill effluent. Environmental Toxicology and Chemistry 2006;25(4):1026-1033.  [Abstract: PubMed | Abstract: Wiley] R826130 (1999)
    Journal ArticleJenkins RL, Wilson EM, Angus RA, Howell WM, Kirk M. Androstenedione and progesterone in the sediment of a river receiving paper mill effluent. Toxicological Sciences 2003;73(1):53-59.  [Full-text: Toxicological Sciences - Full Text HTML | Abstract: Toxicological Sciences | Other: Toxicological Sciences - Full Text PDF] R826130 (1999)
    Journal ArticleJenkins RL, Wilson EM, Angus RA, Howell WM, Kirk M, Moore R, Nance M, Brown A. Production of androgens by microbial transformation of progesterone in vitro: a model for androgen production in rivers receiving paper mill effluent. Environmental Health Perspectives 2004;112(15):1508-1511.  [Abstract: PubMed | Full-text: EHP - Full Text PDF | Abstract: EHP] R826130 (1999)
    Journal ArticleJenkins R, Angus RA, McNatt H, Howell WM, Kemppainen JA, Kirk M, Wilson EM. Identification of androstenedione in a river containing paper mill effluent. Environmental Toxicology and Chemistry 2001;20(6):1325-1331.  [Abstract: PubMed | Abstract: Wiley] R826130 (1999)
    Journal ArticleMiller CL, Angus RA. Preliminary studies on the use of Poeciliid fishes as sensitive bioindicators of environmental androgens. Journal of the Alabama Academy of Science 1997;68:137. R826130 (1999)
    Journal ArticleThomas P, Rahman MS, Kummer JA, Lawson S. Reproductive endocrine dysfunction in Atlantic croaker exposed to hypoxia. Marine Environmental Research 2006;62(Suppl 1):S249-S252.  [Abstract: PubMed | Full-text: Science Direct - Full Text HTML | Abstract: Science Direct | Other: Science Direct - Full Text PDF] R826130 (1999)
    R829458C005 (2005)
    Journal ArticleTolar JF, Watson RD, Angus RA. Development of a quantitative enzyme-linked immunosorbent assay for vitellogenin of mosquitofish (Gambusia affinis). Journal of the Alabama Academy of Science 1998;69:68. R826130 (1999)
    Journal ArticleTolar JF, Mehollin AR, Watson RD, Angus RA. Mosquitofish (Gambusia affinis) vitellogenin: identification, purification, and immunoassay. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology 2001;128(2):237-245.  [Abstract: PubMed | Full-text: ScienceDirect - Full Text HTML | Abstract: ScienceDirect | Other: ScienceDirect - Full Text PDF] R826130 (1999)


    R826131 - Anti-androgenic Pesticides: Impact on Male Reproduction:

  • Journal Article (5)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleRao Veeramachaneni DN, Sharpe RM, Skakkeb‘k NE, McLachlan J. Germ cell atypia in undescended testes hinges on the aetiology of cryptorchidism but not the abdominal location per se. International Journal of Andrology 2006;29(1):235-240 R826131 (2002)
    Journal ArticleVandewoude S, Palmer J, Veeramachaneni DN. Surgical induction of cryptorchidism in rabbit pups. Laboratory Animal Science 1999;49(1):110-113 R826131 (2002)
    Journal ArticleVeeramachaneni DN. Deteriorating trends in male reproduction: idiopathic or environmental?. Animal Reproduction Science 2000;60:121-130 R826131 (2002)
    Journal ArticleVeeramachaneni DN, Palmer JS, Amann RP, Kane CM, Higuchi T, Pau KY. Disruption of sexual function, FSH secretion, and spermiogenesis in rabbits following developmental exposure to vinclozolin, a fungicide. Reproduction 2006;131(4):805-816 R826131 (2002)
    Journal ArticleVeeramachaneni DN, Vandewoude S. Interstitial cell tumour and germ cell tumour with carcinoma in situ in rabbit testes. International Journal of Andrology 1999;22(2):97-101 R826131 (2002)


    R826132 - Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary:

  • Journal Article (6)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGao X, Terranova PF, Rozman KK. Effects of polychlorinated dibenzofurans, biphenyls, and their mixture with dibenzo-p-dioxins on ovulation in the gonadotropin-primed immature rat: support for the toxic equivalency concept. Toxicology and Applied Pharmacology 2000;163(2):115-124.  [Abstract: PubMed | Full-text: ScienceDirect-PDF | Abstract: ScienceDirect-Abstract] R826132 (1999)
    Journal ArticleGao X, Petroff BK, Rozman KK, Terranova PF. Gonadotropin-releasing hormone (GnRH) partially reverses the inhibitory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on ovulation in the immature gonadotropin-treated rat. Toxicology 2000;147(1):15-22.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R826132 (1999)
    Journal ArticleGao X, Son DS, Terranova PF, Rozman KK. Toxic equivalency factors of polychlorinated dibenzo-p-dioxins in an ovulation model: validation of the toxic equivalency concept for one aspect of endocrine disruption. Toxicology and Applied Pharmacology 1999;157(2):107-116.  [Abstract: PubMed | Full-text: ScienceDirect-PDF | Abstract: ScienceDirect-Abstract] R826132 (1999)
    Journal ArticlePetroff BK, Gao X, Ohshima KI, Shi FX, Son DS, Roby KF, Rozman KK, Watanabe G, Taya K, Terranova PF. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reproductive Toxicology 2002;16(2):97-105.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R826132 (1999)
    Journal ArticlePetroff BK, Gao X, Rozman KK, Terranova, PF. Interaction of estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in an ovulation model: evidence for systemic potentiation and local ovarian effects. Reproductive Toxicology 2000;14(3):247-255.  [Abstract: PubMed | Full-text: ScienceDirect-Full-Text | Other: ScienceDirect-PDF] R826132 (1999)
    Journal ArticleSon DS, Ushinohama K, Gao X, Taylor CC, Roby KF, Rozman KK, Terranova PF. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) blocks ovulation by a direct action on the ovary without alteration of ovarian steroidogenesis: lack of a direct effect on ovarian granulosa and thecal-interstitial cell steroidogenesis in vitro. Reproductive Toxicology 1999;13(6):521-530.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R826132 (1999)


    R826133 - Computational Tools for the Prediction and Classification of Estrogenic Compounds:

  • Journal Article (15)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal Article DeLisle RK, Yu SJ, Nair AC, Welsh WJ. Homology modeling of the estrogen receptor subtype β (ER-β) and calculation of ligand binding affinities. Journal of Molecular Graphics & Modelling 2001;20(2):155-167 R826133 (F)
    Journal ArticleFang H, Tong WD, Welsh WJ, Sheehan DM. QSAR models in receptor-mediated effects: the nuclear receptor superfamily. Journal of Molecular Structure-Theochem 2003;622(1-2):113-125 R826133 (F)
    Journal ArticleOuyang M, Welsh WJ, Georgopoulos P. Gaussian mixture clustering and imputation of microarray data. Bioinformatics 2004;20(6):917-923 R826133 (F)
    Journal ArticlePerkins R, Fang H, Tong WD, Welsh WJ. Quantitative structure-activity relationship methods: Perspectives on drug discovery and toxicology. Environmental Toxicology and Chemistry 2003;22(8):1666-1679. R826133 (F)
    Journal ArticlePuri S, Chickos JS, Welsh WJ. Determination of vaporization enthalpies of polychlorinated biphenyls by correlation gas chromatography. Analytical Chemistry 2001;73(7):1480-1484. R826133 (F)
    Journal ArticlePuri S, Chickos JS, Welsh WJ. Three-dimensional quantitative structure-property relationship (3D-QSPR) models for prediction of thermodynamic properties of polychlorinated biphenyls (PCBs): Enthalpies of fusion and their application to estimates of enthalpies of sublimation and aqueous solubilities. Journal of Chemical Information and Computer Sciences 2003;43(1):55-62. R826133 (F)
    Journal ArticlePuri S, Chickos JS, Welsh WJ. Three-dimensional quantitative structure-property relationship (3D-QSPR) models for prediction of thermodynamic properties of polychlorinated biphenyls (PCBs): Enthalpy of sublimation. Journal of Chemical Information and Computer Sciences 2002;42(1):109-116. R826133 (F)
    Journal ArticleTabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B. Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environmental Health Perspectives 2004;112(2):163-169. R826133 (F)
    CR830686 (2003)
    CR830686 (2006)
    Journal ArticleTamura H, Yoshikawa H, Gaido KW, Ross SM, DeLisle RK, Welsh WJ, Richard AM. Interaction of organophosphate pesticides and related compounds with the androgen receptor. Environmental Health Perspectives 2003;111(4):545-552 R826133 (F)
    Journal ArticleTong W, Welsh WJ, Shi LM, Fang H, Perkins R. Structure-activity relationship approaches and applications. Environmental Toxicology and Chemistry 2003;22(8):1680-1695. R826133 (F)
    Journal ArticleTong W, Lowis DR, Perkins R, Chen Y, Welsh WJ, Goddette DW, Heritage TW, Sheehan DM. Evaluation of quantitative structure-activity relationship methods for large-scale prediction of chemicals binding to the estrogen receptor. 1998;38(4):669-677. R826133 (F)
    Journal ArticleXing L,Welsh WJ, Tong W, Perkins R, Sheehan DM. Comparison of estrogen receptor α and β subtypes based on comparative molecular field analysis (CoMFA). SAR and QSAR in Environmental Research 1999;10(2-3):215-237. R826133 (F)
    Journal ArticleYoon S, Welsh WJ. Identification of a minimal subset of receptor conformations for improved multiple conformation docking and two-step scoring. Journal of Chemical Information and Computer Sciences 2004;44(1):88-96 R826133 (F)
    Journal ArticleYu SJ, Keenan SM, Tong W, Welsh WJ. Influence of the structural diversity of data sets on the statistical quality of three-dimensional quantitative-activity relationship (3D-QSAR) models: Predicting the estrogenic activity of xenoestrogens. Chemical Research in Toxicology 2002;15(10):1229-1234 R826133 (F)
    Journal ArticleZauhar RJ, Moyna G, Tian LF, Li ZJ, Welsh WJ. Shape signatures: A new approach to computer-aided ligand- and receptor-based drug design. Journal of Medicinal Chemistry 2003;46(26):5674-5690 R826133 (F)


    R826134 - Stages in Sublethal Exposure to EDCs in a Quail Model System:

  • Journal Article (16)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleAbdelnabi MA, Richards MP, Ottinger MA. Comparison of gonadal hormone levels in turkey embryos incubated in long-term shell-less culture and in ovo. Poultry Science 2001;80(5):666-669 R826134 (0)
    Journal ArticleAbdelnabi MA, Ottinger MA. Hypothalamic indolamines during embryonic development and effects of steroid exposure. General and Comparative Endocrinology 2003;130(1):13-19 R826134 (0)
    Journal ArticleAbdelnabi MA, Bakst MR, Woods JE, Ottinger MA. Plasma 17 beta-estradiol levels and ovarian interstitial cell structure in embryonic Japanese quail. Poultry Science 2000;79(4):564-567 R826134 (0)
    Journal ArticleCatena ML, Porter TE, McNabb FM, Ottinger AA. Cloning of a partial cDNA for Japanese quail thyroid-stimulating hormone beta and effects of methimazole on the thyroid and reproductive axes. Poultry Science 2003;82(3):381-387 R826134 (0)
    R827400 (F)
    Journal ArticleLin F, Wu J, Abdelnabi MA, Ottinger MA, Giusti MM. Effects of dose and glycosylation on the transfer of genistein into the eggs of the Japanese quail (Coturnix japonica). Journal of Agricultural and Food Chemistry 2004;52(8):2397-2403 R826134 (0)
    Journal ArticleMcGary S, Henry PF, Ottinger MA. Impact of vinclozolin on reproductive behavior and endocrinology in Japanese quail (Coturnix coturnix japonica). Environmental Toxicology and Chemistry 2001;20(11):2487-2493 R826134 (0)
    Journal ArticleOttinger MA, Wu JM, Hazelton JL, Abdelnabi MA, Thompson N, Quinn ML, Donoghue D, Schenck F, Ruscio M, Beavers J, Jaber M. Assessing the consequences of the pesticide methoxychlor: neuroendocrine and behavioral measures as indicators of biological impact of an estrogenic environmental chemical. Brain Research Bulletin 2005;65(3):199-209 R826134 (0)
    Journal ArticleOttinger MA, Kubakawa K, Kikuchi M, Thompson N, Ishii S. Effects of exogenous testosterone on testicular luteinizing hormone and follicle-stimulating hormone receptors during aging. Experimental Biology and Medicine 2002;227(9):830-836 R826134 (0)
    Journal ArticleOttinger MA, Rattner BA. Husbandry and care of quail. Poultry and Avian Biology Reviews 1999;10(2):117-120 R826134 (0)
    Journal ArticleOttinger MA, Abdelnabi MA, Henry P, McGary S, Thompson N, Wu JM. Neuroendocrine and behavioral implications of endocrine disrupting chemicals in quail. Hormones and Behavior 2001;40(2):234-247 R826134 (0)
    Journal ArticleOttinger MA. Quail and other short-lived birds. Experimental Gerontology 2001;36(4-6):859-868 R826134 (0)
    Journal ArticleOttinger MA, Abdelnabi M, Quinn M, Golden N, Wu J, Thompson N. Reproductive consequences of EDCs in birds - What do laboratory effects mean in field species?. Neurotoxicology and Teratology 2002;24(1):17-28 R826134 (0)
    Journal ArticleOttinger MA, Pitts S, Abdelnabi MA. Steroid hormones during embryonic development in Japanese quail: Plasma, gonadal, and adrenal levels. Poultry Science 2001;80(6):795-799 R826134 (0)
    Journal ArticlePollack SJ, Ottinger MA, Sullivan CV, Woods LC. The effects of the soy isoflavone genistein on the reproductive development of striped bass. North American Journal of Aquaculture 2003;65(3):226-234 R826134 (0)
    Journal ArticleQuinn MJ, French JB, McNabb FMA, Ottinger MA. The effects of polychlorinated biphenyls (Aroclor 1242) on thyroxine, estradiol, molt, and plumage characteristics in the American kestrel (Falco sparverius). Environmental Toxicology and Chemistry 2002;21(7):1417-1422. R826134 (0)
    R827400 (F)
    Journal ArticleVann SL, Sparling DW, Ottinger MA. Effects of white phosphorus on mallard reproduction. Environmental Toxicology and Chemistry 2000;19(10):2525-2531 R826134 (0)


    R826297 - Endocrine Disruptors: Effects on the Thyroid:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleMartin LA. Differential effects of polychlorinated biphenyl (PCB) mixtures and congeners on the disposition of thyroxine(T4). Toxicol.Sci. 2002;60:Abstr 1314 R826297 (F)
    Journal ArticleMartin LA, Gallo MA, Ruehl KR, Klassen CD. Rapid dissappearance of intravenously administered [125]I-thyroxine (T4) from serum following repeated administration of polychlorinated biphenyls (PCBs). Toxicologist 2001;60:380-381 R826297 (F)


    R826298 - Environmental Endocrine Disruption in Avian Wildlife:

  • Journal Article (4)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleEl-Sabeawy F, Enan E, Lasley B. Biochemical and toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in immature male and female chickens. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2001;129(4):317-327.  [Abstract: PubMed | Full-text: ScienceDirect-PDF | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-PDF] R826298 (F)
    Journal ArticleStanton BJ, Watkins SM, German JB, Lasley BL. Effect of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on plasma fatty acids of immature male chickens (Gallus domesticus). Comparative Biochemistry and Physiology Part C:Toxicology & Pharmacology 2002;132(2):129-142.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R826298 (F)
    Journal ArticleStanton B, DeWitt J, Henshel D, Watkins S, Lasley B. Fatty acid metabolism in neonatal chickens (Gallus domesticus) treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 3,3 ',4,4 ',5-pentachlorobiphenyl (PCB-126) in ovo. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2003;136(1):73-84.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R826298 (F)
    Journal ArticleStanton B, Watkins S, German JB, Lasley B. Interaction of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with hepatic fatty acid synthesis and metabolism of male chickens (Gallus domesticus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2001;129(2):137-150.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R826298 (2000)
    R826298 (F)
    R825433 (F)


    R826299 - Effects of Early Exposure to Xenoestrogens on the Prostate Gland:

  • Book Chapter (1)
  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterPutz O, Prins GS, Burnstein KL. Prostate Gland Development and Estrogenic Imprinting. Springer, New York, NY. 2002;5:73-89 R826299 (1999)
    Journal ArticleGilleran JP, Putz O, DeJong M, DeJong S, Birch L, Pu YB, Huang LW, Prins GS. The role of prolactin in the prostatic inflammatory response to neonatal estrogen. Endocrinology 2003;144(5):2046-2054 R826299 (1999)
    Journal ArticlePrins GS, Birch L, Habermann H, Chang WY, Tebeau C, Putz O, Bieberich C. Influence of neonatal estrogens on rat prostate development. Reproduction Fertility and Development 2001;13(4):241-252 R826299 (1999)
    Journal ArticlePutz O, Schwartz CB, Kim S, LeBlanc GA, Cooper RL, Prins GS. Neonatal low- and high-dose exposure to estradiol benzoate in the male rat: I. Effects on the prostate gland. Biology of Reproduction 2001;65(5):1496-1505. R826299 (1999)
    R826129 (2001)
    R826129 (F)


    R826300 - Dioxin and Steroid Regulation in an Endometriosis Model:

  • Book Chapter (2)
  • Journal Article (7)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterBruner KL, Keller NR, Osteen KG, Lemay A, Lemay Andre, Maheux R. Interleukin-1α opposes suppression of human endometrial matrix metalloproteinases by progesterone in a model of experimental endometriosis. Taylor & Francis . 1999;18:123-130 R826300 (1999)
    R826300 (F)
    Book ChapterBruner KL, Keller NR, Osteen KG, Lemay A, Maheux R. Interleukin-1(Alpha) opposes suppression of human endometrial matrix metalloproteinases by progesterone in a model of experimental endometriosis. Informa Healthcare, 1999;6:123-130 R826300 (F)
    Journal ArticleBofinger DP, Feng L, Chi LH, Love J, Stephen FD, Sutter TR, Osteen KG, Costich TG, Batt RE, Koury ST, Olson JR. Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. Toxicological Sciences 2001;62(2):299-314. R826300 (F)
    Journal Article Bruner KL, Etsenberg E, Gorstein F, Osteen KG. Progesterone and transforming growth factor-β coordinately regulate suppression of endometrial matrix metalloproteinases in a model of experimental endometriosis. Steroids 1999;64(9):648-653 R826300 (1999)
    R826300 (F)
    Journal ArticleBruner-Tran KL, Eisenberg E, Yeaman GR, Anderson TA, McBean J, Osteen KG. Steroid and cytokine regulation of matrix metalloproteinase expression in endometriosis and the establishment of experimental endometriosis in nude mice. Journal of Clinical Endocrinology and Metabolism 2002;87(10):4782-4791. R826300 (F)
    Journal ArticleBruner-Tran KL, Rier SE, Eisenberg E, Osteen KG. The potential role of environmental toxins in the pathophysiology of endometriosis. Obstetric and Gynecologic Investigation 1999;48:45-56. R826300 (1999)
    R826300 (F)
    Journal ArticleCurry TE, Osteen KG. Cyclic changes in the matrix metalloproteinase system in the ovary and uterus. Biology of Reproduction 2001;64(5):1285-1296. R826300 (F)
    Journal ArticleIgarashi TM, Bruner-Tran KL, Yeaman GR, Lessey BA, Edwards DP, Eisenberg E, Osteen KG. Reduced expression of progesteron receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fertility and Sterility 2005;84(1):67-74 R826300 (F)
    Journal ArticleOsteen KG, Keller NR, Feltus FA, Melner MH. Paracrine regulation of matrix metalloproteinase expression in the normal human endometrium. Gynecologic and Obstetric Investigation 1999;48(Suppl 1):2-8. R826300 (1999)
    R826300 (F)


    R826301 - Species-Specific Endocrine Disruption: PCB- and PAH-Induced Estrogenic Effects:

  • Book Chapter (1)
  • Journal Article (10)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterZacharewski T, Fertuck K, Fielden M, Matthews J. Mechanistically-based assays for the identification and characterization of endocrine disruptors. In: Vanden Heuvel JP, Greenlee WF, Perdew GH, Mattes WB, eds. Comprehensive Toxicology Volume 14: Cellular and Molecular Toxicology. Elsiever Science B.V., Amsterdam, The Netherlands, 2002, pp. 559-582. R826301 (2001)
    R826301 (F)
    R827402 (2001)
    R827402 (F)
    Journal ArticleCelius T, Matthews JB, Giesy JP, Zacharewski TR. Quantification of rainbow trout (Oncorhynchus mykiss) zona radiata and vitellogenin mRNA levels using real-time PCR after in vivo treatment with estradiol-17 beta or alpha-zearalenol. Journal of Steroid Biochemistry and Molecular Biology 2000;75(2-3):109-119. R826301 (2000)
    R826301 (F)
    Journal ArticleFertuck KC, Matthews JB, Zacharewski TR. Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo. Toxicological Sciences 2001;59(2):231-240. R826301 (2001)
    R826301 (F)
    Journal ArticleFertuck KC, Kumar S, Sikka HC, Matthews JB, Zacharewski TR. Interaction of PAH-related compounds with the and isoforms of estrogen receptor. Toxicology Letters 2001;121(3):167-177. R826301 (2001)
    R826301 (F)
    R826192 (F)
    Journal ArticleHuang YW, Matthews JB, Fertuck KC, Zacharewski TR. Use of Xenopus laevis as a model for investigating in vitro and in vivo endocrine disruption in amphibians. Environmental Toxicology and Chemistry 2005;24(8):2002-2009 R826301 (F)
    Journal ArticleMatthews JB, Fertuck KC, Celius T, Huang YW, Fong CJ, Zacharewski TR. Ability of structurally diverse natural products and synthetic chemicals to induce gene expression mediated by estrogen receptors from various species. Journal of Steroid Biochemistry and Molecular Biology 2002;82(2-3):181-194 R826301 (F)
    Journal ArticleMatthews JB, Twomey K, Zacharewski TR. In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors alpha and beta. Chemical Research in Toxicology 2001;14(2):149-157 R826301 (F)
    Journal Article Matthews JB, Clemons JH, Zacharewski TR. Reciprocal mutagenesis between human α(L349, M528) and rainbow trout (M317, I496) estrogen receptor residues demonstrates their importance in ligand binding and gene expression at different temperatures. Molecular and Cellular Endocrinology 2001;183(1-2):127-139 R826301 (2001)
    R826301 (F)
    Journal ArticleMatthews J, Zacharewski T. Differential binding affinities of PCBs, HO-PCBs, and aroclors with recombinant human, rainbow trout (Onchorhynkiss mykiss), and green anole (Anolis carolinensis) estrogen receptors, using a semi-high throughput competitive binding assay. Toxicological Sciences 2000;53(2):326-339. R826301 (1999)
    R826301 (F)
    Journal ArticleMatthews J, Celius T, Halgren R, Zacharewski T. Differential estrogen receptor binding of estrogenic substances: a species comparison. Journal of Steroid Biochemistry and Molecular Biology 2000;74(4):223-234. R826301 (2001)
    Journal ArticleRosen G, O'Bryant E, Matthews J, Zacharewski T, Wade J. Distribution of androgen receptor mRNA expression and immunoreactivity in the brain of the green anole lizard. Journal of Neuroendocrinology 2002;14(1):19-28. R826301 (2001)
    R826301 (F)


    R826310 - Exposure and Response of Morelet's Crocodile (Crocodylus moreletii) Populations to Endocrine Disrupting Compounds in Belize, Central America:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleRainwater TR, Wu TH, Finger AG, Canas JE, Yu L, Reynolds KD, Coimbatore G, Barr B, Platt SG, Cobb GP, Anderson TA, McMurry ST. Metals and organochlorine pesticides in caudal scutes of crocodiles from Belize and Costa Rica. Science of the Total Environment 2007;373(1):146-156 R826310 (F)
    Journal ArticleWu TH, Canas JE, Rainwater TR, Platt SG, McMurry ST, Anderson TA. Organochlorine contaminants in complete clutches of Morelet's crocodile (Crocodylus moreletii) eggs from Belize. Environmental Pollution 2006;144(1):151-157 R826310 (F)


    R827399 - Evaluation of Endocrine-Distrupting Chemical Effects Across Multiple Levels of Biological Organization: Integration of Physiology Behavior and Population Dynamics In Fishes:

  • Journal Article (1)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleMurphy CA, Rose KA, Alvarez MC, Fuiman LA. Modeling larval fish behavior:scaling the sublethal effects of methylmercury to population-relevant endpoints. Aquatic Toxicology 2008;86(4):470-484.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct PDF] R829458 (2005)
    R827399 (2001)


    Endocrine Disruptors (1999):

    R827397 - Environmentally-Mediated Endocrine Disruption in Estuarine Crustaceans: A 3-Taxon Multi-Generational Study of Sediment-Associated EDC Effects from the Genetic to Population Levels:

  • Journal Article (26)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBejarano AC, Pennington PL, DeLorenzo ME, Chandler GT. Atrazine effects on meiobenthic assemblages of a modular estuarine mesocosm. Marine Pollution Bulletin 2005;50(11):1398-1404 R827397 (F)
    Journal ArticleBejarano AC, Chandler GT. Reproductive and developmental effects of atrazine on the estuarine meiobenthic copepod Amphiascus tenuiremis. Environmental Toxicology and Chemistry 2003;22(12):3009-3016. R827397 (2002)
    R827397 (F)
    Journal ArticleBlock DS, Bejarano AC, Chandler GT. Ecdysteroid concentrations through various life-stages of the meiobenthic harpacticoid copepod, Amphiascus tenuiremis and the benthic estuarine amphipod, Leptocheirus plumulosus. General and Comparative Endocrinology 2003;132(1):151-160. R827397 (2002)
    R827397 (F)
    Journal ArticleCary TL, Chandler GT, Volz DC, Walse SS, Ferry JL. Phenylpyrazole insecticide fipronil induces male infertility in the estuarine meiobenthic crustacean Amphiascus tenuiremis. Environmental Science & Technology 2004;38(2):522-528.  [Full-text: ACS Publications Full Text | Other: ACS Publications PDF] R827397 (2002)
    R827397 (F)
    Journal ArticleChandler GT, Green AS. Developmental stage-specific life-cycle bioassay for assessment of sediment-associated toxicant effects on benthic copepod production. Environmental Toxicology and Chemistry 2001;20(1):171-178.  [Abstract: PubMed | Abstract: Wiley-Abstract] R827397 (2000)
    R827397 (2002)
    R827397 (F)
    R825279 (F)
    R826399E02 (F)
    Journal ArticleChandler GT, Cary TL, Volz DC, Walse SS, Ferry JL, Klosterhaus SL. Fipronil effects on estuarine copepod (Amphiascus tenuiremis) development, fertility, and reproduction: A rapid life-cycle assay in 96-well microplate format. Environmental Toxicology and Chemistry 2004;23(1):117-124. R827397 (F)
    Journal ArticleChandler GT, Cary TL, Bejarano AC, Pender J, Ferry JL. Population consequences of fipronil and degradates to copepods at field concentrations: An integration of life cycle testing with Leslie matrix population Modeling. Environmental Science & Technology 2004;38(23):6407-6414 R827397 (F)
    Journal ArticleChandler GT, Volz DC. Semi quantitative confocal laser scanning microscopy applied to marine invertebrate ecotoxicology. Marine Biotechnology 2004;6(2):128-137. R827397 (2002)
    R827397 (F)
    Journal ArticleChandler G, Volz DC, Cary TL. Standard guide for conducting renewal microplate-based life-cycle toxicity tests with marine meiobenthic copepods. ASTM Standards for Aquatic Toxicology and Hazard Evaluation. R827397 (2002)
    R827397 (F)
    Journal ArticleGriffitt RJ, Chandler GT, Greig TW, Quattro JM. Cathepsin B and glutathione peroxidase show differing transcriptional responses in the grass shrimp, Palaemonetes pugio following exposure to three xenobiotics. Environmental Science & Technology 2006;40(11):3640-3645 R827397 (F)
    Journal ArticleKong L, Ferry JL. Effect of salinity on the photolysis of chrysene adsorbed to a smectite clay. Environmental Science & Technology 2003;37(21):4894-4900.  [Full-text: ACS Full Text | Other: ACS PDF] R827397 (2002)
    R827397 (F)
    Journal ArticleKong L, Ferry JL. Photochemical oxidation of chrysene at the silica gel-water interface. Journal of Photochemistry and Photobiology A-Chemistry 2004;162(2-3):415-421. R827397 (F)
    Journal ArticleSchizas NV, Chandler GT, Coull BC, Klosterhaus SL, Quattro JM. Differential survival of three mitochondrial lineages of a marine benthic copepod exposed to a pesticide mixture. Environmental Science & Technology 2001;35(3):535-538.  [Abstract: PubMed | Full-text: ResearchGate - Abstract & Full Text HMTL | Abstract: ES&T-Abstract | Other: ResearchGate - Full Text PDF] R827397 (2002)
    R827397 (F)
    R825439 (1999)
    R825439 (F)
    R825279 (F)
    R826399E02 (F)
    Journal ArticleSchizas N, Coull B, Chandler G, Quattro J. Sympatry of distinct mitochondrial DNA lineages in a copepod inhabiting estuarine creeks in the southeastern USA. Marine Biology 2002;140(3):585-594.  [Abstract: SpringerLink Abstract] R827397 (2002)
    R827397 (F)
    R825439 (1999)
    R825439 (F)
    R826399E02 (F)
    Journal ArticleStaton JL, Schizas NV, Chandler GT, Coull BC, Quattro JM. Ecotoxicology and population genetics: The emergence of "phylogeographic and evolutionary ecotoxicology". Ecotoxicology 2001;10(4):217-222. R827397 (2002)
    R827397 (F)
    Journal ArticleStaton JL, Schizas NV, Klosterhaus SL, Griffitt RJ, Chandler GT, Coull BC. Effect of salinity variation and pesticide exposure on an estuarine harpacticoid copepod, Microarthridion littorale (Poppe), in the southeastern US. Journal of Experimental Marine Biology and Ecology 2002;278(2):101-110. R827397 (F)
    Journal ArticleVolz DC, Chandler GT. An enzyme-linked immunosorbent assay for lipovitellin quantification in copepods: A screening tool for endocrine toxicity. Environmental Toxicology and Chemistry 2004;23(2):298-305. R827397 (2002)
    R827397 (F)
    Journal ArticleVolz DC, Wirth EF, Fulton MH, Scott GI, Strozier E, Block DS, Ferry JL, Walse SS, Chandler GT. Effects of fipronil and chlorpyrifos on endocrine-related endpoints in female grass shrimp (Palaemonetes pugio). Bulletin of Environmental Contamination and Toxicology 2003;71(3):497-503. R827397 (2002)
    R827397 (F)
    Journal ArticleVolz DC, Wirth EF, Fulton MH, Scott GI, Block DS, Chandler GT. Endocrine-mediated effects of UV-A irradiation on grass shrimp (Palaemonetes pugio) reproduction. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology 2002;133(3):419-434. R827397 (2002)
    R827397 (F)
    Journal ArticleVolz DC, Kawaguchi T, Chandler GT. Purification and characterization of the common yolk protein, vitellin, from the estuarine amphipod Leptocheirus plumulosus. Preparative Biochemistry & Biotechnology 2002;32(2):103-119. R827397 (2002)
    R827397 (F)
    Journal ArticleWalse SS, Morgan SL, Kong L, Ferry JL. Role of dissolved organic matter, nitrate, and bicarbonate in the photolysis of aqueous fipronil. Environmental Science & Technology 2004;38(14):3908-3915. R829397 (F)
    R827397 (F)
    Journal ArticleWalse SS, Scott GI, Ferry JL. Stereoselective degradation of aqueous endosulfan in modular estuarine mesocosms: formation of endosulfan gamma-hydroxycarboxylate. Journal of Environmental Monitoring 2003;5(3):373-379. R829397 (F)
    R827397 (F)
    Journal ArticleWalse SS, Shimizu KD, Ferry JL. Surface-catalyzed transformations of aqueous endosulfan. Environmental Science & Technology 2002;36(22):4846-4853. R829397 (F)
    R827397 (2002)
    R827397 (F)
    Journal ArticleWirth EF, Lund SA, Fulton MH, Scott GI. Determination of acute mortality in adults and sublethal embryo responses of Palaemonetes pugio to endosulfan and methoprene exposure. Aquatic Toxicology 2001;53(1):9-18. R827397 (2000)
    R827397 (2002)
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    Journal ArticleWirth EF, Lund SA, Fulton MH, Scott GI. Reproductive alterations in adult grass shrimp, Palaemonetes pugio, following sublethal, chronic endosulfan exposure. Aquatic Toxicology 2002;59(1-2):93-99. R827397 (2002)
    R827397 (F)
    Journal ArticleWirth EF, Pennington PL, Lawton JC, DeLorenzo ME, Bearden D, Shaddrix B, Sivertsen S, Fulton MH. The effects of the contemporary-use insecticide (fipronil) in an estuarine mesocosm. Environmental Pollution 2004;131(3):365-371. R827397 (2002)
    R827397 (F)


    R827398 - Frog Deformities: Role of Endocrine Disruptors During Development:

  • Journal Article (1)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGardiner D, Ndayibagira A, Grun F, Blumberg B. Deformed frogs and environmental retinoids. Pure and Applied Chemistry 2003;75(11-12):2263-2273. R827398 (F)


    R827400 - Field and Laboratory Studies of the Effects of Polychlorinated Biphenyls and Other Persistent Organic Pollutants on Thyroid Function During Avian Development:

  • Book Chapter (3)
  • Journal Article (5)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterMcNabb FM, Dawson A, Chaturvedi CM. Maternal thyroid hormones in avian eggs: Potential for pollutant disruption of thyroid hormone deposition and effects on embryonic development. Narosa Publishing House, New Delhi, India. 2002;15:219-230 R827400 (F)
    Book ChapterMcNabb FM, McCleary RJ, Fowler LA, Parsons CM, Grasman KA, Fox GA, Goos HJ, Rastogi RK, Vaudry H, Pierantoni R, Goos HJ, Rastogi RK, Vaudry H, Pierantoni R. Thyroid function in polychlorinated biphenyl (PCB)-exposed avian ambryos and chicks. Monduzzi Editore, Bologna, Italy. 2001;275-280 R827400 (F)
    Book ChapterMcnabb FMA, McCleary RJR, Fowler LA, Parsons CM, Grasman KA, Fox GA, Goos H, Rastogi R, Vaudry H, Pierantoni R. Thyroid function in PCB-exposed avian embryos and chicks. In: Goos HJTh, Rastogi RK, Vaudry H, Pierantoni R, eds. Perspectives in Comparative Endocrinology: Unity and Diversity. Monduzzi Editore, Napoli, Italy. 2001:127-139 R827400 (F)
    Journal ArticleCatena ML, Porter TE, McNabb FM, Ottinger AA. Cloning of a partial cDNA for Japanese quail thyroid-stimulating hormone beta and effects of methimazole on the thyroid and reproductive axes. Poultry Science 2003;82(3):381-387 R826134 (0)
    R827400 (F)
    Journal ArticleMcNabb FM. Biomarkers for the assessment of avian thyroid disruption by chemical contaminants. Avian and Poultry Biology Reviews 2005;16(1):3-10 R827400 (F)
    Journal ArticleMcNabb FMA, Fox GA. Avian thyroid development in chemically contaminated environments: is there evidence of alterations in thyroid function and development? Evolution & Development 2003;5(1):76-82. R827400 (F)
    Journal ArticleQuinn MJ, French JB, McNabb FMA, Ottinger MA. The effects of polychlorinated biphenyls (Aroclor 1242) on thyroxine, estradiol, molt, and plumage characteristics in the American kestrel (Falco sparverius). Environmental Toxicology and Chemistry 2002;21(7):1417-1422. R826134 (0)
    R827400 (F)
    Journal ArticleScanes CG, McNabb FM. Avian models for research in toxicology and endocrine disruption. Avian and Poultry Biology Reviews 2003;14(1):21-52 R827400 (F)


    R827401 - Endocrine Disruption in Marine Gastropods by Environmental Chemical Mixtures:

  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBurger J, Fossi C, McClellan-Green P, Orlando EF. Methodologies, bioindicators, and biomarkers for assessing gender-related differences in wildlife exposed to environmental chemicals. Environmental Research 2007;104(1):135-152 R827401 (2001)
    Journal Article Halgren RG, Fielden MR, Fong CJ, Zacharewski TR. Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones. Nucleic Acids Research 2001;29(2):582-588 R827401 (2001)
    R827402 (2001)
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    Journal ArticleMcClellan-Green P, Romano J, Oberdorster E. Does gender really matter in contaminant exposure? A case study using invertebrate models. Environmental Research 2007;104(1):183-191 R827401 (2001)
    Journal ArticleOberdorster E, McClellan-Green P. Mechanisms of imposex induction in the mud snail, Ilyanassa obsoleta: TBT as a neurotoxin and aromatase inhibitor. Marine Environmental Research 2002;53(3-5):715-718, Special Issue. R827401 (2001)
    Journal ArticleOberdorster E. Peptide hormones versus steroid hormones: Case studies from snail and turtle populations. Environmental Hormones: the Scientific Basis of Endocrine Disruption 2001;948:75-79 R827401 (2001)
    Journal ArticleOberdorster E, Romano J, McClellan-Green P. The neuropeptide APGWamide as a penis morphogenic factor (PMF) in gastropod mollusks. Integrative and Comparative Biology 2005;45(1):28-32 R827401 (2001)
    Journal ArticleOberdorster E, McClellan-Green P. The neuropeptide APGWamide induces imposer in the mud snail, Ilyanassa obsoleta. Peptides 2000;21(9):1323-1330. R827401 (2001)
    Journal ArticleRittschof D, McClellan-Green P. Molluscs as multidisciplinary models in environment toxicology. Marine Pollution Bulletin 2005;50(4):369-373 R827401 (2001)


    R827402 - Developmental Exposure to Endocrine Disruptors: Fertility and Gene Expression Profiles:

  • Book Chapter (1)
  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterZacharewski T, Fertuck K, Fielden M, Matthews J. Mechanistically-based assays for the identification and characterization of endocrine disruptors. In: Vanden Heuvel JP, Greenlee WF, Perdew GH, Mattes WB, eds. Comprehensive Toxicology Volume 14: Cellular and Molecular Toxicology. Elsiever Science B.V., Amsterdam, The Netherlands, 2002, pp. 559-582. R826301 (2001)
    R826301 (F)
    R827402 (2001)
    R827402 (F)
    Journal ArticleFielden MR, Zacharewski TR. Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology. Toxicological Sciences 2001;60(1):6-10. R827402 (2001)
    R827402 (F)
    Journal ArticleFielden MR, Samy SM, Chou KC, Zacharewski TR. Effect of human dietary exposure levels of genistein during gestation and lactation on reproductive development and sperm quality in mice. Food Chemistry and Toxicology 2003;41(4):447-454. R827402 (F)
    Journal ArticleFielden MR, Halgren RG, Dere E, Zacharewski TR. GP3: GenePix post-processing program for automated analysis of raw microarray data. Bioinformatics 2002;18(5):771-773. R827402 (2001)
    R827402 (F)
    Journal ArticleFielden MR, Halgren RG, Fong CJ, Staub C, Johnson L, Chou K, Zacharewski TR. Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the testis, sperm fertilizing ability in vitro, and testicular gene expression. Endocrinology 2002;143(8):3044-3059. R827402 (F)
    Journal ArticleFielden MR, Matthews JB, Fertuck KC, Halgren RG, Zacharewski TR. In silico approaches to mechanistic and predictive toxicology: An introduction to bioinformatics for toxicologists. Critical Reviews in Toxicology 2002;32(2):67-112. R827402 (2001)
    R827402 (F)
    Journal ArticleFielden MR, Fong CJ, Haslam SZ, Zacharewski TR. Normal mammary gland morphology in pubertal female mice following in utero and lactational exposure to genistein at levels comparable to human dietary exposure. Toxicology Letters 2002;133(2-3):181-191. R827402 (F)
    Journal Article Halgren RG, Fielden MR, Fong CJ, Zacharewski TR. Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones. Nucleic Acids Research 2001;29(2):582-588 R827401 (2001)
    R827402 (2001)
    R827402 (F)
    Journal ArticleSaama PM. Sparse preconditioned iterative solvers for ill-posed mixed model equations. Society for Industrial and Applied Mathematics Journal on Numerical Analysis. R827402 (F)


    R827403 - Effects of an Endocrine Disruptor on Prostate Development and Growth:

  • Book Chapter (2)
  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book Chapter Naz RK. Endocrine Disruptors: Effects on Male and Female Reproductive Systems, Second Edition. CRC, . 2004: R827403 (F)
    Book ChapterRichter CA, Timms BG, vom Saal FS. Prostate development: mechanisms for opposite effects of low and high doses of estrogenic chemicals. In: Naz RK, ed. Endocrine Disruptors: Effects on Male and Female Reproductive Systems, Second Ed. Boca Raton, FL: CRC Press. R827403 (F)
    Journal ArticleThomson AA, Timms BG, Barton L, Cunha GR, Grace OC. The role of smooth muscle in regulating prostatic induction. Development 2002;129(8):1905-1912. R827403 (F)
    Journal ArticleTimms BG, Howdeshell KL, Barton L, Bradley S, Richter CA, Vom Saal FS. Estrogenic chemicals in plastic and oral contraceptives disrupt the fetal mouse prostate and urethra. Biology of Reproduction 2005;102(19):7014-7019. . R827403 (F)


    R827404 - Endocrine Disruption in Adolescence:

  • Journal Article (4)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGolub MS. Cognitive testing (delayed non-match to sample) during oral treatment of female adolescent monkeys with the estrogenic pesticide methoxychlor. Neurotoxicology and Teratology 2002;24(1):87-92. R827404 (F)
    Journal ArticleGolub MS, Hogrefe CE, Germann SL, Lasley BL, Natarajan K, Tarantal AF. Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys. Toxicological Sciences 2003;74(1):103-113. R827404 (F)
    Journal ArticleGolub MS, Germann SL, Hogrefe CE. Endocrine disruption and cognitive function in adolescent female rhesus monkeys. Neurotoxicology and Teratology 2004;26(6):799-809. R827404 (F)
    Journal ArticleGolub MS, Hogrefe CE, Germann SL, Jerome CP. Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys. Toxicological Sciences 2004;82(2):598-607. R827404 (F)


    R827405 - Endocrine Disruptors and Testis Development:

  • Journal Article (12)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleAnway MD, Cupp AS, Uzumcu M, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors and mate fertility. Science 2005;308(5727):1466-1469 R827405 (F)
    Journal ArticleAnway MD, Memon MA, Uzumcu M, Skinner MK. Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis. Journal of Andrology 2006;27(6):868-879 R827405 (F)
    Journal Article Cupp AS, Skinner MK. Actions of the endocrine disrupter methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth. Reproductive Toxicology 2001;15(3):317-326 R827405 (2001)
    R827405 (F)
    Journal ArticleCupp AS, Uzumcu M, Skinner MK. Chemotactic role of neurotropin 3 in the embryonic testis that facilitates morphological male sex determination. Biology of Reproduction 2003;68(6):2033-2037. R827405 (F)
    Journal ArticleCupp AS, Uzumcu M, Suzuki H, Dirks H, Phillips B, Skinner MK. Effect of transient embryonic in vivo exposure to the endocrine disruptor methoxychlor on embryonic and postnatal testis development. Journal of Andrology 2003;24(5):736-745. R827405 (2001)
    R827405 (F)
    Journal ArticleCupp AS, Tessarollo L, Skinner MK. Testis developmental phenotypes in neurotropin receptor trkA and trkC null mutations: Role in seminiferous cords germ cell survival. Biology of Reproduction 2002;66(6):1838-1845. R827405 (F)
    Journal ArticleLevine E, Cupp AS, Skinner MK. Role of neurotropins in rat embryonic testis morphogenesis (cord formation). Biology of Reproduction 2000;62(1):132-142. R827405 (2001)
    R827405 (F)
    Journal Article Levine E, Cupp AS, Miyashiro L, Skinner MK. Role of transforming growth factor-α and the epidermal growth factor receptor in embryonic rat testis development. Biology of Reproduction 2000;62(3):477-490 R827405 (2001)
    R827405 (F)
    Journal ArticleSkinner MK, Anway MD. Seminiferous cord formation and germ-cell programming - Epigenetic transgenerational actions of endocrine disruptors. Ann N Y Acad Sci 2005;1061(Testicular Cell Dynamics and Endocrine Signaling):18-32 R827405 (F)
    Journal ArticleUzumcu M, Suzuki H, Skinner MK. Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function. Reproductive Toxicology 2004;18(6):765-774. R827405 (F)
    Journal ArticleUzumcu M, Westfall SD, Dirks KA, Skinner MK. Embryonic testis cord formation and mesonephric cell migration requires the phosphotidylinositol 3-kinase signaling pathway. Biology of Reproduction 2002;67(6):1927-1935. R827405 (F)
    Journal ArticleUzumcu M, Dirks KA, Skinner MK. Inhibition of platelet-derived growth factor actions in the embryonic testis influences normal cord development and morphology. Biology of Reproduction 2002;66(3):745-753 R827405 (F)


    Endocrine Disruptors: Epidemiologic Approaches (2001):

    R829436 - Study of Phthalates in Pregnant Woman and Children:

  • Book (1)
  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    BookSwan SH, Guillette Jr., LJ, Myers JP, vom Saal FS. Epidemiological studies of reproductive effects in humans. In: Jorgensen SE, Fath BD, eds. Encyclopedia of Ecology. 1st Edition, Elsevier, BV, Oxford, 2008, pp. 1383-1388.  [Abstract: Science Direct] R829436 (F)
    Journal ArticleMarsee K, Woodruff TJ, Axelrad DA, Calafat AM, Swan SH. Estimated daily phthalate exposures in a population mothers of male infants exhibiting reduced anogenital distance. Environmental Health Perspectives 2006;114(6):805-809.  [Abstract: PubMed | Full-text: EHP | Other: EHP PDF] R829436 (2005)
    R829436 (F)
    Journal ArticleSathyanarayana S, Karr CJ, Lozano P, Brown E, Calafat AM, Liu F, Swan SH. Baby care products:possible sources of infant phthalate exposure. Pediatrics 2008;121(2):e260-e268.  [Abstract: PubMed | Full-text: Pediatrics | Other: Pediatrics PDF] R829436 (F)
    Journal ArticleSathyanarayana S, Calafat AM, Liu F, Swan SH. Maternal and infant urinary phthalate metabolite concentrations: are they related? Environmental Research 2008;108(3):413-418.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct pdf] R829436 (F)
    Journal ArticleSwan SH, Main K, Kruse R, Stewart S, Redmon B, Ternand C, Sullivan S. Anogenital Distance and Phthalate Exposure:Swan et al Repond. (response to letter to the editor) Environmental Health Perspectives 2006;114(1):A20-A21. R829436 (F)
    Journal ArticleSwan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, Mao CS, Redmon JB, Ternand CL, Sullivan S, Teague JL. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environmental Health Perspectives 2005;113(8):1056-1061.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R829436 (2005)
    R829436 (F)
    Journal ArticleSwan SH. Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans. Environmental Research 2008;108(2):177-184.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct] R829436 (F)
    Journal ArticleSwan SH. Prenatal phthalate exposure and anogenital distance in male infants. (letter to the editor) Environmental Health Perspectives 2006;114 (2):A88-89.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R829436 (F)
    Journal ArticleSwan SH. Semen quality in fertile US men in relation to geographical area and pesticide exposure. International Journal of Andrology 2006;29(1):62-68.  [Abstract: PubMed] R829436 (F)


    R829437 - Dioxins, Male Pubertal Development and Testis Function:

  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBurns JS, Williams PL, Sergeyev O, Korrick S, Lee MM, Revich B, Altshul L, Patterson Jr. DG, Turner WE, Needham LL, Shararov I, Hauser R. Predictors of serum dioxins and PCBs among peripubertal Russian boys. Environmental Health Perspectives 2009;117(10):1593-1599.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: EHP] R829437 (F)
    Journal ArticleBurns JS, Williams PL, Sergeyev O, Korrick S, Lee MM, Revich B, Altshul L, Turner WE, Patterson DG, Saharov I, Hauser R. Predictors of serum dioxins and PCBs in a Russian cohort of boys. Organohalogen Compounds 2008;70:1490-1493. R829437 (F)
    Journal ArticleHauser R, Sergeyev O, Korrick S, Lee MM, Revich B, Gitin E, Burns JS, Williams PL. Association of blood lead levels with onset of puberty in Russian boys. Environmental Health Perspectives 2008;116(7):976-980.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: EHP | Abstract: EHP | Other: EHP PDF] R829437 (2007)
    R829437 (F)
    Journal ArticleHauser R, Williams P, Altshul L, Korrick S, Peeples L, Patterson Jr. DG, Turner WE, Lee MM, Revich B, Zeilert V, Sergeyev O. Characterization and predictors of serum dioxin levels among adolescent boys in Chapaevsk, Russia. Organohalogen Compounds 2004;66:3245-3251. R829437 (2004)
    R829437 (2006)
    R829437 (2007)
    R829437 (F)
    Journal ArticleHauser R, Williams P, Altshul L, Korrick S, Peeples L, Patterson DG Jr, Turner WE, Lee MM, Revich B, Sergeyev O. Predictors of serum dioxin levels among adolescent boys in Chapaevsk, Russia: a cross-sectional pilot study. Environmental Health: A Global Access Science Source 2005;4(1):8.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: Environmental Health | Other: Environmental Health PDF] R829437 (2004)
    R829437 (2006)
    R829437 (2007)
    R829437 (F)
    Journal ArticleLee MM, Sergeyev O, Williams P, Korrick S, Zeilert V, Revich B, Hauser R. Physical growth and sexual maturation of boys in Chapaevsk, Russia. Journal of Pediatric Endocrinology & Metabolism 2003;16(2):169-178.  [Abstract: PubMed | Abstract: Reference Global] R829437 (2003)
    R829437 (2006)
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    R829437 (F)
    Journal ArticleMilnes MR, Bryan TA, Medina JG, Gunderson MP, Guillette Jr. LJ. Developmental alterations as a result of in ovo exposure to the pesticide metabolite p,p '-DDE in Alligator mississippiensis. General and Comparative Endocrinology 2005;144(3):257-263.  [Full-text: Science Direct HTML | Abstract: Science Direct | Other: ] R829437 (F)
    R824760 (F)
    Journal ArticleSergeyev O, Revich B, Williams P, Korrick S, Zeilert V, Lee MM, Ushakova T, Saharov I, Altshul L, Hauser R. A case-cohort study of cryptorchidism, hypospadias and delayed sexual maturation in a dioxin contaminated region: Chapaevsk, Russia. Organohalogen Compounds 2002;59:385-388. R829437 (2004)
    R829437 (2006)
    R829437 (2007)
    R829437 (F)


    R830254 - Endocrine Disrupting Chemicals and Thyroid Outcomes:

  • Book Chapter (1)
  • Journal Article (25)
  • Reference Type Citation [Document Sources] Progress Report Year
    Book ChapterAnderson HA, Bigler JD. Development of programs to monitor methyl-mercury exposure and issue fish consumption advisories. Chapter 29. In: Pirrone N, Mahaffey KR, eds. Dynamics of Mercury Pollution on Regional and Global Scales. New York, NY: Springer, 2005, Part IV, pp. 491-509.  [Abstract: Springer] R830254 (F)
    Journal ArticleAnderson HA. Eighth International Conference on Mercury as a Global Pollutant (ICMGP): human health and exposure to methylmercury. Environmental Research 2008;107(1):1-3.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct] R830254 (F)
    Journal ArticleAnderson HA, Imm P, Knobeloch L, Turyk M, Mathew J, Buelow C, Persky V. Polybrominated diphenyl ethers (PBDE) in serum: findings from a US cohort of consumers of sport-caught fish. Chemosphere 2008;73(2):187-194.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct PDF] R830254 (F)
    Journal ArticleAnderson HA, Wolff MS. Special fish contaminants issue. Environmental Research 2005;97(2):125-126 (introductory commentary).  [Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R830254 (F)
    R831711 (2004)
    R831711 (2005)
    R831711 (2006)
    R831711 (2007)
    R831711 (F)
    R831711C002 (2006)
    R831711C001 (2006)
    R831711C003 (2006)
    Journal ArticleAnderson HA, Hanrahan LP, Smith A, Draheim L, Kanarek M, Olsen J. The role of sport-fish consumption advisories in mercury risk communication:a 1998-1999 12-state survey of women age 18-45. Environmental Research 2004;95(3):315-324.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct] R830254 (F)
    Journal ArticleFreels S, Chary LK, Turyk M, Piorkowski J, Mallin K, Dimos J, Anderson H, McCann K, Burse V, Persky V. Congener profiles of occupational PCB exposure versus PCB exposure from fish consumption. Chemosphere 2007;69(3):435-443.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct PDF] R830254 (2007)
    R830254 (F)
    Journal ArticleGliori G, Imm P, Anderson HA, Knobeloch L. Fish consumption and advisory awareness among expectant women. Wisconsin Medical Journal 2006;105(2):41-44.  [Abstract: PubMed | Full-text: WMJ] R830254 (F)
    Journal ArticleImm P, Knobeloch L, Anderson HA. Fish consumption and advisory awareness in the Great Lakes basin. Environmental Health Perspectives 2005;113(10):1325-1329.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleImm P, Knobeloch L, Buelow C, Anderson HA. Household exposures to polybrominated diphenyl ethers (PBDEs) in a Wisconsin cohort. Environmental Health Perspectives 2009;117(12):1890-1895.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleImm P, Knobeloch L, Anderson HA. Maternal recall of children's consumption of commercial and sport-caught fish:findings from a multi-state study. Environmental Research 2007;103(2):198-204.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: ] R830254 (F)
    Journal ArticleKnobeloch L, Gliori G, Anderson H. Assessment of methylmercury exposure in Wisconsin. Environmental Research 2007;103(2):205-210.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct] R830254 (F)
    Journal ArticleKnobeloch L, Anderson HA, Imm P, Peters D, Smith A. Fish consumption, advisory awareness, and hair mercury levels among women of childbearing age. Environmental Research 2005;97(2):220-227.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct] R830254 (F)
    Journal ArticleKnobeloch L, Anderson HA. Human biomonitoring to optimize fish consumption advice. American Journal of Public Health 2005;95(8):1304.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleKnobeloch L, Steenport D, Schrank C, Anderson H. Methylmercury exposure in Wisconsin:a case study series. Environmental Research 2006;101(1):113-122.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct] R830254 (F)
    Journal ArticleKnobeloch L, Turyk M, Imm P, Schrank C, Anderson H. Temporal changes in PCB and DDE levels among a cohort of frequent and infrequent consumers of Great Lakes sportfish. Environmental Research 2009;109(1):66-72.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct PDF] R830254 (F)
    Journal ArticleMcElroy JA, Kanarek MS, Trentham-Dietz A, Robert SA, Hampton JM, Newcomb PA, Anderson HA, Remington PL. Potential exposure to PCBs, DDT, and PBDEs from sport-caught fish consumption in relation to breast cancer risk in Wisconsin. Environmental Health Perspectives 2004;112(2):156-162.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleMergler D, Anderson HA, Chan LHM, Mahaffey KR, Murray M, Sakamoto M, Stern AH. Methylmercury exposure and health effects in humans: a worldwide concern. Ambio 2007;36(1):3-11.  [Abstract: PubMed | Full-text: Ambio] R830254 (F)
    Journal ArticleTuryk ME, Anderson HA, Freels S, Chatterton Jr. R, Needham LL, Patterson Jr. DG, Steenport DN, Knobeloch L, Imm P, Persky VW, Great Lakes Consortium. Associations of organochlorines with endogenous hormones in male Great Lakes fish consumers and nonconsumers. Environmental Research 2006;102(3):299-307.  [Abstract: PubMed | Full-text: ScienceDirect | Abstract: ScienceDirect | Other: ScienceDirect PDF] R830254 (2005)
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    Journal ArticleTuryk ME, Persky VW, Imm P, Knobeloch L, Chatterton Jr. R, Anderson HA. Hormone disruption by PBDEs in adult male sport fish consumers. Environmental Health Perspectives 2008;116(12):1635-1641.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleTuryk ME, Anderson HA, Persky VW. Relationships of thyroid hormones with polychlorinated biphenyls, dioxins, furans, and DDE in adults. Environmental Health Perspectives 2007;115(8):1197-1203.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (2007)
    R830254 (F)
    Journal ArticleTuryk M, Anderson H, Knobeloch L, Imm P, Persky V. Organochlorine exposure and incidence of diabetes in a cohort of Great Lakes sport fish consumers. Environmental Health Perspectives 2009;117(7):1076-1082.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleTuryk M, Anderson HA, Knobeloch L, Imm P, Persky VW. Prevalence of diabetes and body burdens of polychlorinated biphenyls, polybrominated diphenyl ethers, and p,p'-diphenyldichloroethene in Great Lakes sport fish consumers. Chemosphere 2009;75(5):674-679.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct PDF] R830254 (F)
    Journal ArticleTuryk M, Anderson HA, Hanrahan LP, Falk C, Steenport DN, Needham LL, Patterson Jr. DG, Freels S, Persky V, Great Lakes Consortium. Relationship of serum levels of individual PCB, dioxin, and furan congeners and DDE with Great Lakes sport-caught fish consumption. Environmental Research 2006;100(2):173-183.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct PDF] R830254 (2004)
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    Journal ArticleWeisskopf MG, Anderson HA, Hanrahan LP, The Great Lakes Consortium. Decreased sex ratio following maternal exposure to polychlorinated biphenyls from contaminated Great Lakes sport-caught fish:a retrospective cohort study. Environmental Health:A Global Access Science Source 2003;2(1):2.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed] R830254 (F)
    Journal ArticleWeisskopf MG, Anderson HA, Hanrahan LP, Kanarek MS, Falk CM, Steenport DM, Draheim LA, Great Lakes Consortium. Maternal exposure to Great Lakes sport-caught fish and dichlorodiphenyl dichloroethylene, but not polychlorinated biphenyls, is associated with reduced birth weight. Environmental Research 2005;97(2):149-162.  [Abstract: PubMed | Full-text: ScienceDirect | Abstract: ScienceDirect | Other: ScienceDirect PDF] R830254 (2005)
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    Journal ArticleWolff MS, Anderson HA, Britton JA, Rothman N. Pharmacokinetic variability and modern epidemiology-the example of dichlorodiphenyltrichloroethane, body mass index, and birth cohort. Cancer Epidemiology Biomarkers & Prevention 2007;16(10):1925-1930.  [Abstract: PubMed | Full-text: Cancer Epidemiology Biomarkers & Prevention | Other: Cancer Epidemiology Biomarkers & Prevention] R830254 (F)


    Exposure Measurement Tools for Endocrine Disrupting Chemicals in Mixtures (2005):

    R832737 - Development of Receptor- to Population-Level Analytical Tools for Assessing Endocrine Disruptor Exposure in Wastewater-Impacted Estuarine Systems:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGaertner K, Chandler GT, Quattro J, Ferguson PL, Sabo-Attwood T. Identification and expression of the ecdysone receptor in the harpacticoid copepod, Amphiascus tenuiremis, in response to fipronil. Ecotoxicology and Environmental Safety 2012;76(2):39-45.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R832737 (F)
    Journal ArticleKashiwada S, Tatsuta H, Kameshiro M, Sugaya Y, Sabo-Attwood T, Chandler GT, Ferguson PL, Goka K. Stage-dependent differences in effects of carbaryl on population growth rate in Japanese medaka (Oryzias latipes). Environmental Toxicology and Chemistry 2008;27(11):2397-2402.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R832737 (2008)
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    R832738 - Rapid Detection of Trace Endocrine Disrupting Chemicals in Complex Mixtures: A Full-Spectrum Deconvolution Technique with a UV-Transparent Passive Concentrator:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleKibbey TCG, Chen L, Sabatini DA, Mills MA, Nietch C. Model stream channel testing of a UV-transparent polymer-based passive sampler for ultra-low-cost water screening applications. Chemosphere 2010;80(8):908-913.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect | Other: ScienceDirect-PDF] R832738 (F)
    Journal ArticleKibbey TCG, Chen L, Singhaputtangkul N, Sabatini DA. A UV-transparent passive concentrator/spectrum deconvolution method for simultaneous detection of endocrine disrupting chemicals (EDCs) and related contaminants in natural waters. Chemosphere 2009;76(9):1249-1257.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect | Other: ScienceDirect-PDF] R832738 (F)


    R832739 - Systems Approach to Assessing Cumulative Exposure to Endocrine Disrupting Chemicals:

  • Journal Article (15)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleCrain DA, Eriksen M, Iguchi T, Jobling S, Laufer H, LeBlanc GA, Guillette Jr. LJ. An ecological assessment of bisphenol-A:evidence from comparative biology. Reproductive Toxicology 2007;24(2):225-239.  [Abstract: PubMed | Full-text: Science Direct | Abstract: Science Direct | Other: Science Direct] R832739 (2008)
    Journal ArticleGorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA. A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. Molecular and Cellular Endocrinology 2006;247(1-2):91-102.  [Abstract: PubMed | Full-text: ScienceDirect-FullText HTML | Other: ScienceDirect-PDF] R829358 (F)
    R831300 (2005)
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    Journal ArticleHannas BR, LeBlanc GA. Expression and ecdysteroid responsiveness of the nuclear receptors HR3 and E75 in the crustacean Daphnia magna. Molecular and Cellular Endocrinology 2010;315(1-2):208-218.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R832739 (F)
    Journal ArticleHannas BR, Wang YH, Baldwin WS, Li Y, Wallace AD, LeBlanc GA. Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription. General and Comparative Endocrinology 2010;167(2):268-278.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: ScienceDirect-Full Text | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R832739 (F)
    Journal ArticleHannas BR, Das PC, Li H, LeBlanc GA. Intracellular conversion of environmental nitrate and nitrite to nitric oxide with resulting developmental toxicity to the crustacean Daphnia magna. PLoS ONE 2010;5(8):e12453.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: PLoS-Full Text HTML | Abstract: PLoS-Abstract | Other: PLoS-Full Text PDF] R832739 (F)
    Journal ArticleHannas BR, Wang YH, Thomson S, Kwon G, Li H, LeBlanc GA. Regulation and dysregulation of vitellogenin mRNA accumulation in daphnids (Daphnia magna). Aquatic Toxicology 2011;101(2):351-357.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: ScienceDirect-Full Text | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R832739 (F)
    Journal ArticleLeBlanc GA. Crustacean endocrine toxicology: a review. Ecotoxicology 2007;16(1):61-81.  [Abstract: PubMed | Abstract: Springer-Abstract] R826129 (F)
    R831300 (F)
    R832739 (2007)
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    Journal ArticleMu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. Environmental Toxicology and Chemistry 2005;24(1):146-152.  [Abstract: PubMed | Full-text: ResearchGate-PDF | Abstract: Wiley-Abstract] R829358 (2004)
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    Journal ArticleOlmstead AW, LeBlanc GA. The environmental-endocrine basis of gynandromorphism (intersex) in a crustacean. International Journal of Biological Sciences 2006;3(2):77-84.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: International Journal of Biological Sciences-Full Text HTML | Abstract: International Journal of Biological Sciences-Abstract | Other: International Journal of Biological Sciences-PDF] R831300 (F)
    R832739 (2006)
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    Journal ArticleRider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA. Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. Journal of Experimental Biology 2005;208(Pt 1):15-23.  [Abstract: PubMed | Full-text: JEB-Full Text HTML | Abstract: JEB-Abstract | Other: JEB-PDF] R829358 (F)
    R831300 (2004)
    R831300 (2006)
    R831300 (F)
    R832739 (2008)
    Journal ArticleThomson SA, Baldwin WS, Wang YH, Kwon G, LeBlanc GA. Annotation, phylogenetics, and expression of the nuclear receptors in Daphnia pulex. BMC Genomics 2009;10:500.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: BioMedCentral-Full Text HTML | Abstract: BioMedCentral-Abstract | Other: BioMedCentral-Full Text PDF] R832739 (F)
    Journal ArticleWang HY, Olmstead AW, Li H, LeBlanc GA. The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna. Aquatic Toxicology 2005;74(3):193-204.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R831300 (2005)
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    Journal ArticleWang YH, Wang G, LeBlanc GA. Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna. General and Comparative Endocrinology 2007;150(2):309-318.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R831300 (2006)
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    Journal ArticleWang YH, LeBlanc GA. Interactions of methyl farnesoate and related compounds with a crustacean retinoid X receptor. Molecular and Cellular Endocrinology 2009;309(1-2):109-116.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect-Abstract | Other: ScienceDirect-Full Text PDF] R832739 (2008)
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    Journal ArticleWang YH, Kwon G, Li H, LeBlanc GA. Tributyltin synergizes with 20‐hydroxyecdysone to produce endocrine toxicity. Toxicological Sciences 2011;123(1):71‐79.  [Abstract: PubMed | Full-text: Oxford Journals-Full Text HTML | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-Full Text PDF] R832739 (F)


    R832740 - Integrated Microfluidic System for Bioluminescent Bioreporting, Separations, Vibrational Spectroscopy, and Microcantilever Transducer Evaluation of Endocrine Disrupting Chemicals:

  • Journal Article (26)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleAbu-Hatab NA, John JF, Oran JM, Sepaniak MJ. Multiplexed microfluidic surface-enhanced Raman spectroscopy. Applied Spectroscopy 2007;61(10):1116-1122.  [Abstract: PubMed | Abstract: IngentaConnect-Abstract] R832740 (2007)
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    Journal ArticleAbu-Hatab NA, Oran JM, Sepaniak MJ. Surface-enhanced Raman spectroscopy substrates created via electron beam lithography and nanotransfer printing. ACS Nano 2008;2(2):377-385.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2008)
    R832740 (F)
    Journal ArticleArchibald R, Datskos P, Devault G, Lamberti V, Lavrik N, Noid D, Sepaniak M, Dutta P. Independent component analysis of nanomechanical responses of cantilever arrays. Analytica Chimica Acta 2007;584(1):101-105.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: Science Direct | Other: ScienceDirect-PDF] R832740 (2006)
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    Journal ArticleBhandari D, Wells SM, Retterer SD, Sepaniak MJ. Characterization and detection of uranyl ion sorption on silver surfaces using surface enhanced Raman spectroscopy. Analytical Chemistry 2009;81(19):8061-8067.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (F)
    Journal ArticleBhandari D, Walworth MJ, Sepaniak MJ. Dual function surface-enhanced Raman active extractor for the detection of environmental contaminants. Applied Spectroscopy 2009;63(5):571-578.  [Abstract: PubMed | Abstract: OpticsInfoBase-Abstract] R832740 (2008)
    R832740 (F)
    Journal ArticleChapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ. Differentially ligand-functionalized microcantilever arrays for metal ion identification and sensing. Analytical Chemistry 2007;79(18):7062-7068.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2008)
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    Journal ArticleChapman PJ, Vogt F, Dutta P, Datskos PG, Devault GL, Sepaniak MJ. Facile hyphenation of gas chromatography and a microcantilever array sensor for enhanced selectivity. Analytical Chemistry 2007;79(1):364-370.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2006)
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    Journal ArticleChapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ. Differentially ligand-functionalized microcantilever arrays for metal ion identification and sensing. Analytical Chemistry 2007;79(18):7062-7068.  [Abstract: PubMed] R832740 (2007)
    Journal ArticleConnatser RM, Cochran M, Harrison RJ, Sepaniak MJ. Analytical optimization of nanocomposite surface-enhanced Raman spectroscopy/scattering detection in microfluidic separation devices. Electrophoresis 2008;29(7):1441-1450.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R832740 (2008)
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    Journal ArticleDe Jesus MA, Giesfeldt KS, Oran JM, Abu-Hatab NA, Lavrik NV, Sepaniak MJ. Nanofabrication of densely packed metal-polymer arrays for surface-enhanced Raman spectrometry. Applied Spectroscopy 2005;59(12):1501-1508.  [Abstract: PubMed | Abstract: IngentaConnect-Abstract] R832740 (2008)
    Journal ArticleDutta P, Chapman PJ, Datskos PG, Sepaniak MJ. Characterization of ligand-functionalized microcantilevers for metal ion sensing. Analytical Chemistry 2005;77(20):6601-6608.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2008)
    Journal ArticleDutta P, Hill K, Datskos PG, Sepaniak MJ. Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. Lab on a Chip 2007;7(9):1184-1191.  [Abstract: PubMed | Full-text: National Tsing Hua University PDF | Abstract: RSC Publishing-Abstract] R832740 (2007)
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    Journal ArticleDutta P, Sanseverino J, Datskos PG, Sepaniak MJ. Nanostructured cantilevers as nanomechanical immunosensors for cytokine detection. NanoBiotechnology 2005;1(3):237-244.  [Abstract: SpringerLink-Abstract] R832740 (2008)
    Journal ArticleHill KL, Dutta P, Long Z, Sepaniak MJ. Microcantilever-based nanomechanical studies of the orphan nuclear receptor pregnane X receptor-ligand interactions. Journal of Biomaterials and Nanobiotechnology 2011;2(2):133-142.  [Full-text: SCRIP - Full Text - PDF | Abstract: SCIRP-Abstract & PDF Link] R832740 (F)
    Journal ArticleHill K, Dutta P, Zareba A, Eldridge ML, Sepaniak MJ. Morphological and chemical optimization of microcantilever surfaces for thyroid system biosensing and beyond. Analytica Chimica Acta 2008;625(1):55-62.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R832740 (2007)
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    Journal ArticleLavrik NV, Taylor LC, Sepaniak MJ. Enclosed pillar arrays integrated on a fluidic platform for on-chip separations and analysis. Lab on a Chip 2010;10(8):1086-1094.  [Abstract: PubMed | Abstract: RSC Publishing-Abstract] R832740 (F)
    Journal ArticleLong Z, Hill K, Sepaniak MJ. Aluminium oxide nanostructured microcantilever arrays for nanomechanical-based sensing. Analytical Chemistry 2010;82(10):4114-4121.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (F)
    Journal ArticleLong Z, Storey J, Lewis S, Sepaniak MJ. Landfill siloxane gas sensing using differentiating, responsive phase coated microcantilever arrays. Analytical Chemistry 2009;81(7):2575-2580.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (F)
    Journal ArticleOran JM, Hinde RJ, Abu-Hatab NA, Retterer ST, Sepaniak MJ. Nanofabricated periodic arrays of silver elliptical discs as SERS substrates. Journal of Raman Spectroscopy 2008;39(12):1811-1820.  [Abstract: Wiley Online-Abstract] R832740 (2007)
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    Journal ArticleSanseverino J, Eldridge ML, Layton AC, Easter JP, Yarbrough J, Schultz TW, Sayler GS. Screening of potentially hormonally active chemicals using bioluminescent yeast bioreporters. Toxicological Sciences 2009;107(1):122-134.  [Abstract: PubMed | Full-text: Oxford Journals-Full Text HTML | Abstract: Oxford Journals-Abstract | Other: Oxford Journals-PDF] R832740 (2008)
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    Journal ArticleSenesac LR, Dutta P, Datskos PG, Sepaniak MJ. Analyte species and concentration identification using differentially functionalized microcantilever arrays and artificial neural networks. Analytica Chimica Acta 2006;558(1-2):94-101.  [Full-text: ScienceDirect-Full Text HTML | Abstract: Science Direct | Other: ScienceDirect-PDF] R832740 (2008)
    Journal ArticleStrong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R832740 (F)
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    R831709C003 (2006)
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    Journal ArticleWalworth MJ, Connatser RM, Sepaniak MJ. Extraction, separation, and fluorometric analysis of selected environmental contaminants. Journal of Separation Science 2009;32(17):2985-2992.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R832740 (F)
    Journal ArticleWellman AD, Sepaniak MJ. Magnetically-assisted transport evanescent field fluoroimmunoassay. Analytical Chemistry 2006;78(13):4450-4456.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2006)
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    Journal ArticleWellman AD, Sepaniak MJ. Multiplexed, waveguide approach to magnetically assisted transport evanescent field fluoroassays. Analytical Chemistry 2007;79(17):6622-6628.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (2007)
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    Journal ArticleWells SM, Retterer SD, Oran JM, Sepaniak MJ. Controllable nanofabrication of aggregate-like nanoparticle substrates and evaluation for surface-enhanced Raman spectroscopy. ACS Nano 2009;3(12):3845-3853.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R832740 (F)


    R832741 - Developing Rapid Assessment Tools to Evaluate the Biological Effects of Complex and Biologically Active Chemical Mixtures:

  • Journal Article (8)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBlanksma C, Eguia B, Lott K, Lazorchak JM, Smith ME, Wratschko M, Dawson TD, Elonen C, Kahl M, Schoenfuss HL. Effects of water hardness on skeletal development and growth in juvenile fathead minnows. Aquaculture 2009;286(3-4):226-232.  [Full-text: Science Direct | Abstract: Mendeley abstract | Other: Science Direct PDF] R832741 (2007)
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    Journal ArticleHyndman KM, Biales A, Bartell SE, Schoenfuss HL. Assessing the effects of exposure timing on biomarker expression using 17β-estradiol. Aquatic Toxicology 2010;96(4):264-272.  [Abstract: PubMed | Full-text: Science Direct-Full text | Other: Science Direct-PDF] R832741 (2008)
    Journal ArticleJulius ML, Stepanek J, Tedrow O, Gamble C, Schoenfuss HL. Estrogen-receptor independent effects of two ubiquitous environmental estrogens on Melosira varians Agardh, a common component of the aquatic primary production community. Aquatic Toxicology 2007;85(1):19-27.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: Mendeley abstract | Other: ScienceDirect-PDF] R832741 (2007)
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    Journal ArticleMcGee MR, Julius ML, Vajda AM, Norris DO, Barber LB, Schoenfuss HL. Predator avoidance performance of larval fathead minnows (Pimephales promelas) following short-term exposure to estrogen mixtures. Aquatic Toxicology 2009;91(4):355-361.  [Abstract: PubMed | Full-text: Science Direct | Other: Science Direct PDF] R832741 (2007)
    Journal ArticlePainter MM, Buerkley MA, Julius ML, Vajda AM, Norris DO, Barber LB, Furlong ET, Schultz MM, Schoenfuss HL. Antidepressants at environmentally relevant concentrations affect predator avoidance behavior of larval fathead minnows (Pimephales promelas). Environmental Toxicology and Chemistry 2009;28(12):2677-2684.  [Abstract: PubMed | Full-text: Wiley HTML | Abstract: Wiley | Other: Wiley PDF] R832741 (F)
    Journal ArticleSchoenfuss HL, Bartell SE, Bistodeau TB, Cediel RA, Grove KJ, Zintek L, Lee KE, Barber LB. Impairment of the reproductive potential of male fathead minnows by environmentally relevant exposures to 4-nonylphenolf. Aquatic Toxicology 2008;86(1):91-98.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: Mendeley-Abstract | Other: ScienceDirect-PDF] R832741 (2007)
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    Journal ArticleVajda AM, Barber LB, Gray JL, Lopez EM, Bolden AM, Schoenfuss HL, Norris DO. Demasculinization of male fish by wastewater treatment plant effluent. Aquatic Toxicology 2011;103(3-4):213-221.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R832741 (2008)
    Journal ArticleYe X, Schoenfuss HL, Jahns ND, Delinsky AD, Strynar MJ, Varns J, Nakayama SF, Helfant L, Lindstrom AB. Perfluorinated compounds in common carp (Cyprinus carpio) fillets from the Upper Mississippi River. Environmental International 2008;34(7):932-938.  [Abstract: PubMed | Full-text: Science Direct-PDF | Abstract: ScienceDirect-Full Text HTML | Other: Science Direct PDF] R832741 (2007)
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    Fate and Effects of Hormones in Waste from Concentrated Animal Feeding Operations (CAFOS) (2006):

    R833417 - Fate of Hormones in Tile-Drained Fields and Impact to Aquatic Organisms Under Different Animal Waste Land-Application Practices:

  • Journal Article (7)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleGall HE, Sassman SA, Lee LS, Jafvert CT. Hormone discharges from a midwest tile-drained agroecosystem receiving animal wastes. Environmental Science & Technology 2011;45(20):8755-8764.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R833417 (F)
    Journal ArticleKhan B, Lee LS, Sassman SA. Degradation of synthetic androgens 17α- and 17β-trenbolone and trendione in agricultural soils. Environmental Science and Technology 2008;42(10):3570-3574.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R833417 (2009)
    R833417 (F)
    Journal ArticleKhan B, Lee LS. Soil temperature and moisture effects on the persistence of synthetic androgen 17α-trenbolone, 17β-trenbolone and trendione. Chemosphere 2009;79(8):873-879.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R833417 (F)
    Journal ArticleKhan B, Qiao X, Lee LS. Stereo-selective sorption by agricultural soils and liquid-liquid partitioning of trenbolone (17α and 17β) and trendione. Environmental Science & Technology 2009;43(23):8827–8833.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R833417 (F)
    Journal ArticleLeet JK, Gall HE, Sepulveda MS. A review of studies on androgen and estrogen exposure in fish early life stages:effects on gene and hormonal control of sexual differentiation. 2011;31(5):379-398.  [Abstract: PubMed | Abstract: Wiley Online-Abstract] R833417 (F)
    Journal ArticleMashtare ML, Khan B, Lee LS. Evaluating stereoselective sorption by soils of 17α-estradiol and 17β-estradiol. Chemosphere 2010;82(6):847–852.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Other: ScienceDirect-PDF] R833417 (F)
    Journal ArticleQiao X, Carmosini N, Li F, Lee LS. Probing the primary mechanisms affecting the environmental distribution of estrogen and androgen isomers. Environmental Science & Technology 2011;45(9):3989-3995.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R833417 (F)


    R833418 - Transport/Fate/Ecological Effects of Steroids from Poultry Litter & Evaluations of Existing/Novel Management Strategies:

  • Journal Article (1)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleYonkos LT, Friedel EA, Fisher DJ. Intersex (testicular oocytes) in largemouth bass (Micropterus salmoides) on the Delmarva Peninsula, USA. Environmental Toxicology and Chemistry 2014;33(5):1163-1169.  [Abstract: PubMed | Abstract: Wiley-Abstract] R833418 (2011)


    R833419 - Fate of Hormones in Waste from Concentrated Broiler Feeding Operations:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleBera M, Radcliffe DE, Cabrera ML, Vencill WK, Thompson A, Hassan S. 17-β estradiol and testosterone sorption in soil with and without poultry litter. Journal of Environmental Quality 2011;40(6):1983-1990.  [Abstract: PubMed | Abstract: Journal of Environmental Quality-Abstract] R833419 (2011)
    R833419 (F)
    Journal ArticleDurant MB, Hartel PG, Cabrera ML, Vencill WK. 17-β estradiol and testosterone mineralization and incorporation into organic matter in broiler litter-amended soils. Journal of Environmental Quality 2012;41(6):1923-1930.  [Abstract: PubMed | Abstract: Journal of Environmental Quality-Abstract] R833419 (F)


    R833420 - An Integrated Approach to Developing a Total Facility Estrogen Budget at a Swine Farrowing CAFO:

  • Journal Article (2)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleYost EE, Lee Pow C, Hawkins MB, Kullman SW. Bridging the gap from screening assays to estrogenic effects in fish: potential roles of multiple estrogen receptor subtypes. Environmental Science & Technology 2014;48(9):5211-5219.  [Abstract: PubMed | Abstract: ACS Publications-Abstract] R833420 (F)
    Journal ArticleYost EE, Meyer MT, Dietze JE, Meissner BM, Worley-Davis L, Williams CM, Lee B, Kullman SW. Comprehensive assessment of hormones, phytoestrogens, and estrogenic activity in an anaerobic swine waste lagoon. Environmental Science & Technology 2013;47(23):13781-13790.  [Full-text: PubMed | Abstract: PubMed | Other: PubMed | Full-text: ACS Publications-Full Text HTML | Abstract: ACS Publications-Abstract | Other: ACS Publications-Full Text PDF] R833420 (2011)
    R833420 (F)


    R833421 - Assessing Occurrence, Persistence and Biological Effects of Hormones Released from Livestock Waste:

  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleDeQuattro ZA, Peissig EJ, Antkiewicz DS, Lundgren EJ, Hedman CJ, Hemming JDC, Barry TP. Effects of progesterone on reproduction and embryonic development in the fathead minnow (Pimephales promelas). Environmental Toxicology and Chemistry 2012;31(4):851-856.  [Abstract: PubMed | Abstract: Wiley-Abstract] R833421 (F)
    Journal ArticleHavens SM, Hedman CJ, Hemming JDC, Mieritz MG, Shafer MM, Schauer JJ. Stability, preservation, and quantification of hormones and estrogenic and androgenic activities in surface water runoff. Environmental Toxicology and Chemistry 2010;29(11):2481-2490.  [Abstract: PubMed | Abstract: Environmental Toxicology and Chemistry] R833421 (F)
    Journal ArticleMurack PJ, Parrish J, Barry TP. Effects of progesterone on sperm motility in fathead minnow (Pimephales promelas). Aquatic Toxicology 2011;104(1-2):121-125.  [Abstract: PubMed | Full-text: ScienceDirect-Full Text HTML | Abstract: ScienceDirect | Other: ScienceDirect-PDF] R833421 (F)


    R833422 - Transport and Transformation of Natural and Synthetic Steroid Hormones at Beef Cattle and Dairy Concentrated Animal Feeding Operations (CAFOs):

  • Journal Article (3)
  • Reference Type Citation [Document Sources] Progress Report Year
    Journal ArticleMansell DS, Bryson RJ, Harter T, Webster JP, Kolodziej EP, Sedlak DL. Fate of endogenous steroid hormones in steer feedlots under simulated rainfall-induced runoff. Environmental Science & Technology 2011;45(20):8811-8818.  [Abstract: ES&T Abstract] R833422 (2011)
    R833422 (F)
    Journal ArticleParker JA, Webster JP, Kover SC, Kolodziej EP. Analysis of trenbolone acetate metabolites and melengestrol in environmental matrices using gas chromatography-tandem mass spectrometry. Talanta 2012;99:238-246.  [Abstract: PubMed | Full-text: Science Direct - full text HTML | Abstract: Science Direct | Other: Science Direct - full text PDF] R833422 (F)
    Journal ArticleWebster JP, Kover SC, Bryson RJ, Harter T, Mansell DS, Sedlak DL, Kolodziej EP. Occurrence of trenbolone acetate metabolites in simulated confined animal feeding operation (CAFO) runoff. Environmental Science & Technology 2012;46(7):3803-3810.  [Abstract: PubMed | Abstract: ES&T Abstract] R833422 (2011)
    R833422 (F)