Health Assessment Document for 1,1,2-Trichloro-1,2,2-Trifluoroethane (Chlorofluorocarbon CFC-113)(Revised External Review Draft)
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Abstract
Chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) has little potential to cause direct adverse health effects at levels found or expected in the general environment (<4.2 ppb). Experimental data do not indicate adverse health effects in humans at a TLV of 1,000 ppm. At exposure levels greatly exceeding 1,000 ppm, impairment of neurological and cognitive functions (humans) and detrimental cardiovascular effects (animals) have been observed. A major concern and uncertainty involves its role in the expected depletion of stratospheric ozone. A decrease in the ozone level is expected to result in an increased amount of biologically-damaging radiation at the earth's surface. The lifetime of chlorofluorocarbon 113 in the atmosphere is about 86 years.
Citation
Carchman, R., M. Greenberg, J. Beaubier, AND D. Cronn. Health Assessment Document for 1,1,2-Trichloro-1,2,2-Trifluoroethane (Chlorofluorocarbon CFC-113)(Revised External Review Draft). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-82/002 (NTIS PB83129577), 1982.