Health Assessment Document for Carbon Tetrachloride (Final Report 1984)

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Carbon tetrachloride (CC14) is a haloalkane with a wide range of industrial and chemical applications. Its presence in the atmosphere and in water appears to be of anthropogenic origin. It is readily absorbed through the lung, gastrointestinal tract and skin and, therefore, poses a hazard to human health. This document is an assessment of the literature available up to March 1983, with the exception of the effect of CCl4 on stratospheric ozone, to reflect the most recent development in this area. The scientific literature was inventoried, key studies were evaluated and summaries and conclusions were prepared to qualitatively identify the chemical's toxicity and related characteristics. Observed effect levels and dose-response relationships are discussed evaluating the potential toxicity of CCl4.


DeRosa, C., R. Hertzberg, S. Rosenthal, C. Sonich, AND V. Vaughan-Dellarco. Health Assessment Document for Carbon Tetrachloride (Final Report 1984). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-82/001F (NTIS PB85124196), 1984.

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