US EPA

The Health and Environmental Effects Profile for Isobutanol was prepared to support listings of hazardous constituents of a wide range of waste streams under Section 3001 of the Resource Conservation and Recovery Act (RCRA) and to provide health-related limits for emergency actions under Section 101 of the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA). Both published literature and information obtained from Agency program office files were evaluated as they pertained to potential human health, aquatic life and environmental effects of hazardous waste constituents. Isobutanol has been determined to be a systemic toxicant. An Acceptable Daily Intake (ADI), defined as the amount of a chemical to which humans can be exposed on a daily basis over an extended period of time (usually a lifetime) without suffering a deleterious effect, for isobutanol is 0.3 mg/kg/day for oral exposure. The Reportable Quantity (RQ) value for isobutanol is 1000.

U.S. EPA. Health And Environmental Effects Profile for Isobutanol. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/X-86/149 (NTIS PB89123376).