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This chapter discusses the effects of ozone on experimental animals. Carefully controlled studies of the effects of ozone on animals are particularly important in elucidating subtle effects not easily found in man through epidemiological studies and in identifying chronic toxicity not apparent from short-term controlled human exposures. Animal studies allow investigations into the effects of ozone exposure over a lifetime, uncomplicated by the presence of other pollutants. In the animal experiments presented here, a broad range of ozone concentrations have been studied, and many of the effects of ozone are reasonably well described.
U.S. EPA. Air Quality Criteria for Ozone and Other Photochemical Oxidants. External Review Draft No. 1. Volume Iv. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-84/020A-4 (NTIS PB85126068), 1984.