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Risk Assessment

Integrated Science Assessment for Carbon Monoxide (Final Report)

Notice

EPA is announcing the availability of the final Integrated Science Assessment for Carbon Monoxide as described in the January 29, 2010 Federal Register Notice.

Report Information

EPA has released the final Integrated Science Assessment (ISA) for Carbon Monoxide (CO). This is EPA’s latest evaluation of the scientific literature on the potential human health and welfare effects associated with ambient exposures to CO. The development of this document is part of the Agency's periodic review of the national ambient air quality standards (NAAQS) for CO. The recently completed CO ISA and supplementary annexes, in conjunction with additional technical and policy assessments developed by EPA’s Office of Air and Radiation, will provide the scientific basis to inform EPA decisions related to the review of the current CO NAAQS.

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Tom Long
  • by phone at:   919-541-1880
  • by fax at:   919-541-2985
  • by email at:  long.tom@epa.gov

Background

Cover of the Integrated Science Assessment (ISA) for Carbon Monoxide Carbon monoxide (CO) is one of six principal (or criteria) pollutants for which EPA has established NAAQS. Periodically, EPA reviews the scientific basis for these standards by preparing an Integrated Science Assessment (ISA) (formerly called an Air Quality Criteria Document). The ISA and supplementary annexes, in conjunction with additional technical and policy assessments, provide the scientific basis for EPA decisions on the adequacy of the current NAAQS and the appropriateness of possible alternative standards. The Clean Air Scientific Advisory Committee (CASAC), an independent science advisory committee whose existence and whose review and advisory functions are mandated by Section 109 (d) (2) of the Clean Air Act, is charged (among other things) with independent scientific review of EPA's air quality criteria.

The first and second drafts of the CO ISA were reviewed at public meetings of the CASAC CO Review Panel on May 12-13, 2009 and November 16-17, 2009, respectively. This final CO ISA has benefited from the expert comments received at the CASAC meetings and from public comments, and it has been revised accordingly.

History/Chronology

Mar 1970The National Air Pollution Control Administration published the first Air Quality Criteria for Carbon Monoxide.
Oct 1979EPA released an updated Air Quality Criteria Document for Carbon Monoxide (EPA-600/8-79-022).
Aug 1984EPA published the Revised Evaluation of Health Effects Associated with Carbon Monoxide Exposure: An Addendum to the 1979 EPA Air Quality Criteria Document for Carbon Monoxide (EPA-600/8-83-033F).
Dec 1991EPA published an updated Air Quality Criteria Document for Carbon Monoxide (EPA/600/8-90/045F).
Jun 2000EPA published an updated Air Quality Criteria Document for Carbon Monoxide (EPA/600/P-99/001F).
Aug 2008EPA released the final Plan for Review of the National Ambient Air Quality Standards for Carbon Monoxide (EPA/452/R-08/005).
Mar 2009EPA released the Integrated Science Assessment for Carbon Monoxide (First External Review Draft) (EPA/600/R-09/019) for public review and comment.[Federal Register Mar 12, 2009]
Sep 2009EPA released the Integrated Science Assessment for Carbon Monoxide (Second External Review Draft) (EPA/600/R-09/019B) for public review and comment. [Federal Register Notice September 23, 2009]
Jan 2010EPA releases the Integrated Science Assessment for Carbon Monoxide (Final Report) (EPA/600/R-09/019F).

Next Steps

This is the final document. Additional technical and policy assessment documents for this review are available from the Office of Air Quality Planning and Standards (http://www.epa.gov/ttn/naaqs/standards/co/s_co_index.html).

Citation

U.S. EPA. Integrated Science Assessment for Carbon Monoxide (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-09/019F, 2010.

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