IRIS Process (2008)

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The Integrated Risk Information System (IRIS) is a U.S. Environmental Protection Agency (EPA) database that contains information on human health effects that may result from exposure to chemical substances in the environment. IRIS is maintained by EPA’s Office of Research and Development.

The IRIS process consists of development of a draft Toxicological Review for the chemical, internal and external scientific reviews of the draft document, EPA responses to review comments, and development and posting on the IRIS web site of an IRIS Summary and final Toxicological Review. EPA is announcing revisions to the IRIS process. New steps in the process include increased participation by other federal agencies and the public in the development of the Toxicological Review and opportunities for other federal agencies to conduct research to fill data gaps.

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.