IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft)
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Abstract
The draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to hydrogen cyanide and cyanide salts. Cyanide compounds are used in a number of industrial processes including mining, electroplating, metallurgy, chemical manufacturing, and photography because these compounds can form stable complexes with a range of metals. Hydrogen cyanide is also a component of tobacco smoke, vehicle exhaust, and is produced by the burning of some plastics. Cyanide salts, such as potassium and sodium cyanide, are also used as rodenticides.
Impact/Purpose
Status
Citation
History/Chronology
| Date | Description |
|---|---|
| Jan 1987 | EPA posted an assessment for cyanide salts (RfD only). |
| Sep 1994 | EPA posted an assessment for hydrogen cyanide (RfC only). |
| Jun 2004 | The IRIS reassessment of hydrogen cyanide was initiated in 2004. |
| Sep 2009 | EPA released an external review draft of the assessment for public review and comment. |
| Oct 2009 | EPA announced a public listening session that was held on October 27, 2009 in a September 23, 2009 Federal Register Notice. |
| Nov 2009 | EPA announced the details of an external peer review workshop to be held on December 14, 2009 in a November 10, 2009 Federal Register Notice. |
| Jan 2010 | EPA released the comments from the public comment period and external review workshop. |
Additional Information
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