IRIS Toxicological Review of Hydrogen Cyanide and Cyanide Salts (Interagency Science Discussion Draft)
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The draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to hydrogen cyanide and cyanide salts. Cyanide compounds are used in a number of industrial processes including mining, electroplating, metallurgy, chemical manufacturing, and photography because these compounds can form stable complexes with a range of metals. Hydrogen cyanide is also a component of tobacco smoke, vehicle exhaust, and is produced by the burning of some plastics. Cyanide salts, such as potassium and sodium cyanide, are also used as rodenticides.
|Jan 1987||EPA posted an assessment for cyanide salts (RfD only).|
|Sep 1994||EPA posted an assessment for hydrogen cyanide (RfC only).|
|Jun 2004||The draft IRIS reassessment of hydrogen cyanide was started.|
|Sep 2009||EPA released an external review draft of the assessment for public review and comment.|
|Oct 2009||EPA announced a public listening session to be held on October 27, 2009. [Federal Register Notice Sep 23, 2009]|
|Nov 2009||EPA announced an external peer review workshop to be held on December 14, 2009. [Federal Register Notice Nov 10, 2009]|
|Jan 2010||EPA released the comments from the public comment period and external review workshop.|
|Aug 2010||EPA hosted an interagency science discussion on the review of the draft document.|
|Sep 2010||EPA released the final toxicological report and IRIS Summary for Hydrogen Cyanide and the interagency review draft with comments.|
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