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Environmental Protection Agency Office of Research & Development National Center for Environmental Assessment |
| Summary Report of the Technical Workshop on Issues Associated with Considering Developmental Changes in Behavior and Anatomy when Assessing Exposure to Children | |
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| Summary
Report (PDF file - 17KB) |
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| Appendix
A - List of Panelists & Participants (PDF File - 681KB) |
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Appendix
B - List of Observers |
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| Appendix
C - Charge to the Experts (PDF File - 681KB) |
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| Appendix
D - Agenda (PDF File - 681KB) |
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| Appendix
E - Presenter Overheads (PDF File - 1567KB) |
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| Appendix
F - Behavior Group Overheads (PDF File - 15KB) |
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| Appendix
G - Children's Exposure Assessment (PDF File - 92KB) |
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Appendix
H - Changes In Children's Exposure As A Function Of Age And
The Relevance Of Age Definitions For Exposure And Risk Assessment
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Federal
Register Notice, |
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ABSTRACT:
- The U.S. Environmental Protection Agency's (EPA) Risk Assessment Forum (RAF) announces the availability of the final report, Summary Report of the Technical Workshop on Issues Associated with Considering Developmental Changes in Behavior and Anatomy when Assessing Exposure to Children (EPA/630/R-00/005, December 2000). The report presents information and materials from a peer involvement workshop organized by the RAF. The meeting was held in Washington, DC on July 26 and 27, 2000. The meeting discussions focused on how to consider age-related changes in behavior and physical development when assessing childhood exposures to environmental contaminants. These discussions are part of EPA's ongoing efforts to improve the assessment of risk to children.
- An Agency workgroup convened under the auspices of the RAF has been exploring children's exposure assessment issues. This workgroup has concluded that a major issue facing Agency assessors is how to consider age-related changes in behavior and physiology when preparing exposure assessments for children. Children's behavior changes over time in ways that can have an important impact on exposure. Further, children's physiology changes over time in ways that can impact both their exposures and their susceptibility to certain health effects. There are two aspects to these physiological changes. First, there are anatomical changes resulting from physical growth. Second, there are changes in pharmacokinetics and pharmacodynamics that affect the absorption, distribution, excretion and effects of environmental contaminants. The Agency is examining the pharmacokinetic/ pharmacodynamic changes in children through other efforts and future meetings on this topic are anticipated. The July 2000 workshop focused on incorporating age-related changes in behavior and anatomy into Agency exposure assessments.
- FOR FURTHER INFORMATION CONTACT:
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Steven Knott
Risk Assessment Forum (8601D)
U.S. Environmental Protection Agency
1200 Pennsylvania Avenue, N.W.
Washington DC 20460
telephone: 202-564-3359
facsimile: 202-565-0062
email: knott.steven@epa.gov.
