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EPA's assessment of the noncancer health effects and carcinogenic potential of n-hexane was last prepared and added to the IRIS data base in 1990. The IRIS program is updating the IRIS assessment for n-hexane; this update will incorporate health effects information published since the last assessment was prepared as well as new risk assessment methods. The IRIS assessment for n-hexane will consist of a Toxicological Review and IRIS Summary. The Toxicological Review is a critical review of the physicochemical and toxicokinetic properties of the chemical and its toxicity in humans and experimental systems. The assessment will present reference values for noncancer effects of n-hexane (RfD and RfC) and a cancer assessment, where supported by available data. The Toxicological Review and IRIS Summary will be subject to internal peer consultation, Agency review, and external scientific peer review.
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable
information quality guidelines. It has not been
formally disseminated by EPA. It does not represent and should not be construed to represent any Agency
determination or policy.
|Feb 2005||EPA released the external review draft for public review and comment.|
|Mar 2005||EPA hosted an independent peer review panel workshop to discuss the draft report.|
|Dec 2005||EPA released the final Toxicological Review and IRIS Summary for n-Hexane.|
U.S. EPA. IRIS Toxicological Review and Summary Documents for N-Hexane (External Review Draft). U.S. Environmental Protection Agency, Washington, D.C., EPA/635/R-03/012, 2005.