You are here:
IRIS Toxicological Review and Summary Documents for Xylenes (External Review Draft)
Notice - This site contains archived material(s)
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the NCEA Webmaster for assistance. Please use the contact us form if you need additional assistance.
The cancer weight of evidence determination for mixed xylenes is group D- not classifiable as to human carcinogenicity by the Guidelines for Carcinogen Risk Assessment (1986) and data are inadequate for an assessment of human carcinogenic potential due to conflicting evidence by the revised draft Guidelines for Carcinogen Risk Assessment (1999).
There is limited information on the relative toxicity of the individual isomers and the results are inconsistent. Based on available data, there do not appear to be susceptible populations.
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
To access or download the external review draft xylenes document and related IRIS Summary, please refer to the Downloads/URL Links on the left sidebar.
Please direct any correspondence to: Michael Broder, National Center for Environmental Assessment (8601D), U.S. EPA, 1200 Pennsylvania Ave., NW, Washington, DC 20460 or to email@example.com. Also, please send a record keeping copy to: IRIS Submission Desk, c/o ASRC, 6301 Ivy Lane, Suite 300, Greenbelt, MD 20770. Note that this is a new address for the Submission Desk., or email to