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Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised Aug 2014 External Review Draft)
Federal Register Notices
EPA's Science Advisory Board (SAB) Staff Office has announced two meetings for the SAB Chemical Assessment Advisory Committee (CAAC), augmented for the review of the draft IRIS assessment of ethylene oxide (CAAC-Ethylene oxide panel). The first meeting is a public teleconference scheduled for September 30, 2014. The second is a face-to face panel meeting scheduled for November 18-20, 2014 in Arlington, VA. Additional information about participation in the external peer review meetings, including how to provide comments to the SAB, is available on the SAB website and via the Federal Register.
In August 2014, EPA submitted a revised draft IRIS assessment of ethylene oxide (Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide) to the agency’s SAB and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and then revised it based on the comments received. The SAB CAAC-Ethylene oxide panel will review this draft assessment. Details about the meeting dates and times are available via the August 11, 2014 Federal Register Notice. The SAB provided information on how the public can participate in the external peer review meetings, as well as instructions about how to provide comments to the SAB in the notice. Additional information on the SAB review of ethylene oxide is on the SAB website.
|Jun 1985||EPA published the Health Assessment Document for Ethylene Oxide (EPA-600/8-84/009F).|
|Dec 1998||EPA begins work on new assessment of carcinogenicity of EtO.|
|Mar 2006||Completion of internal EPA review of draft assessment of carcinogenicity of EtO.|
|Aug 2006||Completion of external Federal agencies review of EPA’s draft assessment of carcinogenicity of EtO.|
|Sep 2006||EPA released the draft assessment for a 30-day public comment period. [Federal Register Notice September 22, 2006]|
|Oct 2006||A 30-day extension is given for the public comment period. [Federal Register Notice October 12, 2006]|
|Jan 2007||Peer review meeting of the Science Advisory Board (SAB) (public meeting).|
|Dec 2007||EPA’s SAB issued a final report on the review of the draft assessment of EtO.|
|Jul 2011||EPA initiated Final Agency and Interagency Science Discussion (step 6 of the IRIS process) of the draft assessment of EtO.|
|Jun 2012||EPA conducted further Agency review of a revised draft.|
|Jul 2013||EPA revised the draft assessment and released for additional public review and comment (step 4 of the IRIS process). The interagency science discussion draft of the assessment and related comments are also available. [Federal Register Notice Jul 23, 2013]|
|Aug 2013||EPA announced an extension of the public comment period from September 5 to October 11, 2013. [Federal Register Notice Aug 28, 2013]|
|Aug 2013||EPA’s SAB announced a request for nominations for experts to augment the SAB Chemical Assessment Advisory Committee (CAAC) to form a panel for the review of the EPA’s draft IRIS Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised External Review Draft). [Federal Register Notice Aug 28, 2013]|
|Dec 2013||EPA hosted an IRIS public science meeting to discuss the draft assessment released for public comment.|
|Jul 2014||EPA’s SAB announced the formation of the CAAC panel augmented for the ethylene oxide review.|
|Aug 2014||EPA submitted the draft assessment (revised in response to public comments) to the SAB for external peer review (step 4c of the IRIS process). [Federal Register Notice Aug 11, 2014]|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.