IRIS Toxicological Review of Trimethylbenzenes (Revised External Review Draft)
Federal Register Notices
- J. Allen Davis
- by phone at: 919-541-3789
- by fax at: 919-541-0245
- by email at: firstname.lastname@example.org
- by fax at: 919-541-0245
[UPDATE] To provide the public with additional time to prepare, EPA SAB staff office is rescheduling the February 18-20 meeting of the SAB Chemical Assessment Advisory Committee (CAAC). The EPA SAB staff office will announce a new date in the near future.[UPDATE] In August 2013, EPA submitted a revised draft IRIS assessment of trimethylbenzenes to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and then revised it based on the comments received. The SAB Chemical Assessment Advisory Committee (CAAC), augmented with additional experts, will review this draft assessment. Details about the meeting dates, times, and location are available via the Federal Register Notice posted on January 31, 2014. The SAB provided information on how the public can participate in the external peer review meeting, as well as instructions about how to provide comments to the SAB in the notice. Additional information on the SAB review of trimethylbenzenes is on the SAB website.
Report Information: The Toxicological Review of Trimethylbenzenes was released for a 60-day public comment period on June 29, 2012. [Federal Register Notice Jun 29, 2012] EPA revised the toxicological review in response to the public comments received. Additionally, a summary of major public comments and EPA’s response are included as an appendix in the revised assessment. The full submissions by public commenters are available on the docket at http://www.regulations.gov (Docket ID No. EPA-HQ-ORD-2012-0459). EPA has released the revised external review draft trimethylbenzenes assessment and the SAB CAAC is conducting a peer review of the scientific basis supporting the assessment that will appear in the Integrated Risk Information System (IRIS) database. Please refer to IRISTrack for the latest schedule updates: IRISTrack – 1,2,3-Trimethylbenzene, IRISTrack – 1,2,4-Trimethylbenzene, and IRISTrack – 1,3,5-Trimethylbenzene. Information regarding the peer review including submitting nominations for experts can be found at the SAB web site at http://yosemite.epa.gov/sab/sabproduct.nsf/fedrgstr_activites/IRIS%20Trimethylbenzenes?OpenDocument.
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- (161 pp, 2 MB, about PDF)
- (284 pp, 10 MB, about PDF)
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- (23 pp, 377 KB, about PDF)
- IRIS Toxicological Review of Trimethylbenzenes (External Review Draft) (Jun 2012)
- IRIS Toxicological Review of Trimethylbenzenes (Interagency Science Consultation Draft)
|Feb 2012||EPA hosted an interagency science consultation meeting on the review of the draft Toxicological Review of Trimethylbenzenes.|
|May 2012||EPA sent an abbreviated version of the toxicological review containing only information on 1,2,3-trimethylbenzene for interagency science consultation at the recommendation of reviewers.|
|Jun 2012||EPA released the external peer review draft of the trimethylbenzenes assessment for public review and comment. Additionally, the interagency science consultation draft, comments from reviewers, and EPA’s responses to selected major interagency comments were also released (see "related links"). [Federal Register Notice June 29, 2012]|
|Aug 2013||EPA’s Science Advisory Board (SAB) announced a request for nominations for experts to augment the SAB Chemical Assessment Advisory Committee (CAAC) for the review of the EPA’s draft IRIS assessment for trimethylbenzenes. [Federal Register Notice Aug 28, 2013](3pp., 210KB, about PDF), and made available the revised external review draft assessment and draft charge to peer reviewers.|
|Jan 2014||EPA’s SAB announced a 3-day public peer review meeting for the draft IRIS Toxicological Review of Trimethylbenzenes for Feb 18-20, 2014. [Federal Register Notice Jan 31, 2014]|
|Feb 2014||To provide the public with additional time to prepare, EPA SAB staff office is rescheduling the February 18-20 meeting of the SAB Chemical Assessment Advisory Committee (CAAC). The EPA SAB staff office will announce a new date in the near future.|