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IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft)
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Contact
- Norman Birchfield
- by phone at: 703-347-0174
- by fax at: 703-347-8699
- by email at: birchfield.norman@epa.gov
- by fax at: 703-347-8699
Downloads/Related Links
- IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft) Oct 2011 (PDF) (151 pp, 1 MB, about PDF)
- Draft Charge to External Peer Reviewers (Interagency Science Consultation Draft) Oct 2011 (PDF) (2 pp, 30 KB, about PDF)
- IRIS Toxicological Review of Ammonia (2nd Interagency Science Consultation Draft) Feb 2012 (PDF) (94 pp, 911 KB, about PDF)
- IRIS Toxicological Review of Ammonia, Supplemental Information (2nd Interagency Science Consultation Draft) Feb 2012 (PDF) (65 pp, 701 KB, about PDF)
- Draft Charge to External Peer Reviewers (2nd Interagency Science Consultation Draft) Feb 2012 (PDF) (2 pp, 32 KB, about PDF)
- EPA's Response and Comments from the Interagency Science Consultation (PDF) (4 pp, 56 KB, about PDF)
- 1. CDC ATSDR Ammonia IASC Comments Nov 2011 (PDF) (2 pp, 29 KB, about PDF)
- 2. CDC ATSDR Ammonia IASC Comments Feb 2012 (PDF) (1 pp, 27 KB, about PDF)
- 3. CEQ Ammonia IASC Comments Mar 2012 (PDF) (1 pp, 49 KB, about PDF)
- 4. USDA Ammonia IASC Comments Nov 2011 (PDF) (1 pp, 40 KB, about PDF)
- 5. Consolidated Comments from IRIS Interagency Reviewers on the Format and Preamble in the Science Consultation Draft Ammonia Assessment (PDF) (7 pp, 178 KB, about PDF)
Related Link(s)
Background
About 80% of commercially produced ammonia is used in agricultural fertilizers. Ammonia is also used as a corrosion inhibitor, in water purification, as a household cleaner, as an antimicrobial agent in food products, as a refrigerant, as a stabilizer in the rubber industry, as a source of hydrogen in the hydrogenation of fats and oils, and as a chemical intermediate in the production of pharmaceuticals, explosives, and other chemicals. Ammonia is also used to reduce nitrogen oxide emissions from combustion sources such as industrial and municipal boilers, power generators, and diesel engines. Ammonia is a component of the global nitrogen cycle and is essential to many biologic processes.
History/Chronology
| May 1991 | The RfC for ammonia was posted to the IRIS database. |
| Mar 2012 | EPA hosted an interagency science consultation meeting on the review of the draft Toxicological Review of Ammonia. |
| Jun 2012 | EPA released the external review draft of the ammonia assessment for public review and comment. |
Next Steps
Following external peer review and public comment, the assessment will be revised taking into consideration the comments received. It will then undergo a final internal review by EPA and other federal agencies and White House offices. After completing the review it will be posted to the IRIS database.
Citation
U.S. EPA. IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/013C, 2012.