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Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Interagency Science Discussion Draft)
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Note: After further consideration EPA has decided to undertake an additional peer review of the revised draft assessment on how the Agency responded to the SAB panel recommendations (December 2007), the exposure-response modeling of epidemiologic data, including new analyses since the 2007 external peer review, and on the adequacy, transparency, and clarity of the revised draft assessment.
|Apr 1984||EPA released the Health Assessment Document for Ethylene Oxide (External Review Draft)(EPA-600/8-84/009A).|
|Jun 1985||EPA published the Health Assessment Document for Ethylene Oxide (Final).|
|Dec 1998||EPA begins work on new assessment of carcinogenicity of EtO.|
|Mar 2006||Completion of internal EPA review of draft assessment of carcinogenicity of EtO.|
|Aug 2006||Completion of external Federal agencies review of EPA’s draft assessment of carcinogenicity of EtO.|
|Sep 2006||EPA released the draft assessment for a 30-day public comment period. [Federal Register Notice September 22, 2006]|
|Oct 2006||A 30-day extension is given for the public comment period. [Federal Register Notice October 12, 2006]|
|Nov 2006||EPA released the draft EtO peer review charge and Memo to the Science Advisory Board (SAB) for their review.|
|Jan 2007||Peer review meeting of the SAB (public meeting).|
|Dec 2007||EPA’s SAB issued a final report on the review of the draft assessment of EtO.|
|Jul 2011||EPA initiated Final Agency review and Interagency Science discussion (step 6 of the IRIS process) of the draft assessment of EtO.|
|Jun 2012||EPA conducted further Agency review of the revised draft.|
|Jul 2013||EPA released a revised draft assessment for additional peer review and public review and comment (step 4 of the IRIS process). [Federal Register Notice Jul 23, 2013] The interagency science discussion draft of the assessment and related comments were made available from this site.|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.