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IRIS Toxicological Review of Formaldehyde (Interagency Science Consultation Draft)
Archive disclaimer
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Contact
- Norman Birchfield
- by phone at: 703-347-0174
- by fax at: 703-347-8699
- by email at: birchfield.norman@epa.gov
- by fax at: 703-347-8699
Downloads/Related Links
- Toxicological Review of Formaldehyde (Interagency Science Consulation Draft) Volume I of Iv (PDF) (105 pp, 1 MB, about PDF)
- Toxicological Review of Formaldehyde (Interagency Science Consulation Draft) Volume II of Iv (PDF) (501 pp, 4 MB, about PDF)
- Toxicological Review of Formaldehyde (Interagency Science Consulation Draft) Volume III of Iv (PDF) (276 pp, 2 MB, about PDF)
- Toxicological Review of Formaldehyde (Interagency Science Consulation Draft) Volume Iv of Iv (PDF) (130 pp, 1 MB, about PDF)
- Draft Charge to NAS Panel (PDF) (2 pp, 40 KB, about PDF)
- Comments from ATSDR on the Formaldehyde Tox Review (PDF) (16 pp, 268 KB, about PDF)
- Comments from CEQ on the Formaldehyde Tox Review (PDF) (1 pp, 25 KB, about PDF)
- Comments from CPSC on the Formaldehyde Tox Review (PDF) (11 pp, 115 KB, about PDF)
- Comments from DoD on the Formaldehyde Tox Review (PDF) (3 pp, 46 KB, about PDF)
- Comments from NASA on the Formaldehyde Tox Review (PDF) (3 pp, 72 KB, about PDF)
- Comments from NIOSH on the Formaldehyde Tox Review (PDF) (1 pp, 24 KB, about PDF)
- Comments from OMB on the Formaldehyde Tox Review (PDF) (16 pp, 215 KB, about PDF)
- Comments from DoD on the Charge (PDF) (2 pp, 21 KB, about PDF)
Background
The draft toxicological review of formaldehyde - inhalation assessment provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic inhalation exposure to formaldehyde. Formaldehyde is present in a wide variety of products including some plywood adhesives, abrasive materials, insulation, insecticides and embalming fluids. The major sources of anthropogenic emissions of formaldehyde are motor vehicle exhaust, power plants, manufacturing plants that produce or use formaldehyde or substances that contain it (i.e. glues), petroleum refineries, coking operations, incinerating, wood burning and tobacco smoke.
History/Chronology
| Sep 1990 | The oral RfD for formaldehyde was posted to the IRIS database. |
| May 1991 | The cancer assessment for formaldehyde was posted to the IRIS database. |
| Jan 1998 | EPA begins the formaldehyde reassessment under the IRIS Program. |
| May 2010 | EPA initiated an interagency science consultation on the review of the draft Toxicological Review of formaldehyde. |
| Jun 2010 | EPA released an external review draft of the formaldehyde reassessment for public review and comment. Also released was the interagency review draft with comments. |
Next Steps
Following external peer review the assessment will be revised taking into consideration external peer review and public comments. It will then undergo a final EPA internal review and a review by other federal agencies and White House offices, followed by posting to the IRIS Web site.
Citation
U.S. EPA. IRIS Toxicological Review of Formaldehyde (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-10/002C, 2010.