You are here:
IRIS Toxicological Review of Inorganic Arsenic (Cancer) (2010 External Review Draft)
Federal Register Notices
Notice - This site contains archived material(s)
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the NCEA Webmaster for assistance. Please use the contact us form if you need additional assistance.
|1988||EPA published the IRIS Health Hazard Assessment for Inorganic Arsenic.|
|1999||NRC reviewed the 1988 IRIS assessment and the available health data for inorganic arsenic and made recommendations for updating the cancer assessment in Arsenic in Drinking Water.|
|2001||NRC updated the NRC (1999) report and evaluated the toxicological risk and health effects of arsenic as relevant to the 2001 Arsenic Rule in Arsenic in Drinking Water – 2001 Update.|
|2001||NRC reviewed the 2001 Primary Drinking Water Standard for inorganic Arsenic and made recommendations for applying epidemiologic data in the cancer health assessment.|
|2003||EPA started a reassessment of the IRIS assessment for inorganic arsenic.|
|Jul 2005||EPA submitted the reassessment of cancer assessment for inorganic arsenic to EPA’s Science Advisory Board (SAB) for review.|
|Jun 2007||SAB posted a response to the 2005 EPA reassessment of inorganic arsenic (cancer). [See related links (below) or Link to the SAB Report and Review Panel Meetings]|
|Oct 2008||The draft IRIS Toxicological Review for Inorganic Arsenic (cancer) was submitted to OMB for interagency review.|
|Feb 2010||EPA released the draft IRIS Toxicological Review for Inorganic Arsenic (cancer) to SAB and simultaneously to the public for review and comment, focusing on EPA’s responses to the SAB (2007) report.|
|Oct 2010||SAB announced a public teleconference to conduct a quality review of the draft report to be held on November 22, 2010. [Federal Register Oct 25, 2010]|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
Supporting Documents: The file, Arsenic_Excel_Table 5-3.zip (ZIP, 195 Kb), provides the data and analyses EPA used to derive the cancer risk estimates as described in Table 5-3 in the Toxicological Review of Inorganic Arsenic (Cancer) (External Review Draft) 2010. An additional file (Arsenic_Excel_Appendix F.zip (ZIP, 143 Kb), ) provides the data and analyses EPA used to derive the results presented in Appendix F (Tables F-1 and F-2). Information regarding the files can be found on the first tab (labeled Directions) of each individual Excel® file.