US EPA

The U.S. Environmental Protection Agency (U.S. EPA) and Argonne National Laboratories, through an inter-Agency agreement with the U.S. Department of Energy, convened a workshop that identified and addressed issues related to the dose-response assessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). This report summarizes the discussions and conclusions from that workshop, which was held on February 18−20, 2009, in Cincinnati, Ohio.

U.S. EPA. Summary Of U.S. EPA Dioxin Workshop - Feb 2009. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-09/027, 2009.

In 2003, the U.S. Environmental Protection Agency (U.S. EPA) released a draft report titled Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds (U.S. EPA, 2003). At the request of the U.S. EPA, the National Academy of Sciences (NAS) prepared a report, Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment (NAS, 2006), which made a number of recommendations to improve the U.S. EPA’s reassessment of TCDD (U.S. EPA, 2003). The U.S. EPA and Argonne National Laboratories, through an inter-Agency agreement with the U.S. Department of Energy, convened this scientific workshop (Dioxin Workshop) on February 18−20, 2009, in Cincinnati, Ohio.

The goals of the Dioxin Workshop were to identify and address issues related to the dose-response assessment of TCDD. This Workshop, which was announced in the Federal Register and open to the public, was convened specifically to ensure that the U.S. EPA’s response to the NAS recommendations focuses on the key issues and reflects the most meaningful science. This document provides a summary of the Scientific Workshop to Inform EPA’s Response to National Academy of Science Comments on the Health Effects of Dioxin in EPA’s 2003 Dioxin Reassessment.

Date	Description
01-Oct 2004	EPA released the NAS Review Draft of the Dioxin Assessment, in preparation for the first NAS panel review meeting (held 11/22 -23/04), in Wash., DC.
02-Jul 2006	NAS released Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment.
03-Nov 2008	EPA released a preliminary search list to address EPA's Reponses to the NAS comments on the 2003 Dioxin Reassessment report.
04-Feb 2009	EPA hosted a 3-day public, scientific workshop to assist EPA in responding to the NAS reports on Dioxin. [ Workshop Announcement and details]
05-May 2009	EPA released the 2009 Science Plan for activities related to Dioxins in the environment.
06-Jun 2009	EPA released the summary report from the Draft Dioxin Reassessment Workshop.

This is the Final document.

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

• Summary of U.S. EPA Dioxin Workshop February 18−20, 2009. Cincinnati, Ohio (PDF)  (38 pp, 711 KB, about PDF)
• 2009 Dioxin Re-Assessment Workshop Details and Announcement

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• Preliminary Literature Search on Dioxin 2008
• Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) and Related Compounds (U.S. EPA, 2003)
• Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment (NAS, 2006) 
• NAS Public Summary of the Health Risks from Dioxin and Related Compounds Evaluation of the EPA Reassessment 
• NCEA Dioxin Overview Page (with a History of Dioxin Research)