Chloroform
CASRN 67-66-3
- Toxicological Review (PDF) (112 pp, 759 K)
- IRIS Summary (PDF) (41 pp, 234 K)
- Status: chloroform is in step 3 at this time.
IRIS Toxicological Review of Chloroform (Final Report, 2001)
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Overview
Citation
U.S. EPA. IRIS Toxicological Review of Chloroform (Final Report, 2001). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-01/001, 2001.
Background
Chloroform (trichloromethane) is a colorless, volatile liquid with a distinct odor. Chloroform is nonflammable. It is slightly soluble in water and is readily miscible with most organic solvents. Because chloroform is relatively volatile, it tends to escape from contaminated environmental media (e.g., water or soil) into air, and may also be released in vapor form from some types of industrial or chemical operations. Therefore, humans may be exposed to chloroform not only by ingestion of chloroform in drinking water, food, or soil, but also by dermal contact with contaminated media (especially water) and by inhalation of vapor (especially in indoor air).
History/Chronology
| Date | Description |
|---|---|
| Sep 1984 | EPA released the Health Effects Assessment for Chloroform. |
| Apr 1988 | EPA released the Updated Health Effects Assessment for Chloroform. |
| Oct 2001 | EPA released the final tox report and summary document and posted these to the IRIS database. |
Download(s)
This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.
- IRIS Toxicological Review and Summary Documents for Chloroform (2001 Final) (PDF) (112 pp, 935 KB, about PDF)
- IRIS Summary of Chloroform (PDF) (39 pp, 237 KB, about PDF)
- BMDS Modeling for Chloroform (ZIP) (198 KB, about ZIP)
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