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Propargite Quickview (CASRN 2312-35-8)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Propargite

File First On-Line: 05/01/1990; Last Significant Revision: 05/01/1990

Category (section)
Status
Last Revised
Oral RfD Assessment On-line 05/01/1990
Inhalation RfC Assessment No data
Carcinogenicity Assessment No data
Synonyms
  • Comite
  • Cyclosulfyne
  • D014
  • ENT 27226
  • Naugatuck d014
  • Omite
  • Omite 57 e
  • Omite 85 e
  • Propargil
  • 2312-35-8
  • Propargite
  • more...
Propargite Source Documents
Revision History
Date Section Description
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
UF RfD
No adverse effects observed at the HDT NOEL : 2.25 x101 mg/kg-day 1000 2 x10-2 mg/kg-day
(Systemic effects)
Reduced body weight gain; increased resorption, reduced body weight, delayed ossification (maternal and fetal) NOEL : 2.0 mg/kg-day 100 2 x10-2 mg/kg-day
(Maternal toxicity and fetotoxicity)

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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