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Cerium Oxide and Cerium Compounds Quickview (CASRN 1306-38-3)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for Cerium Oxide and Cerium Compounds

File First On-Line: 09/29/2009; Last Significant Revision: 09/29/2009

Category (section)
Last Revised
Oral RfD Assessment Discussion 09/29/2009
Inhalation RfC Assessment Yes 09/29/2009
Carcinogenicity Assessment Yes 09/29/2009
  • Cerium oxide and cerium compounds
  • 1306-38-3
  • ceric oxide
  • cerium dioxide
  • ceria
  • cerium oxide
Revision History
Date Section Description
09/29/2009 I., II. RfD, RfC, and cancer assessment first on-line
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Information reviewed but value not estimated. See IRIS Summary.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Increased incidence of alveolar epithelial hyperplasia in the lungs of male and female rats BMCL (HEC): 0.86 mg/m3 1000 9x10-4 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • Inadequate information to assess carcinogenic potential
  • Weight-of-Evidence Narrative:
    • In accordance with U.S. EPA (2005a) Guidelines for Carcinogen Risk Assessment, there is "inadequate information to assess the carcinogenic potential" of cerium in humans.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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