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2-Methylnaphthalene Quickview (CASRN 91-57-6)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the IRIS Summary to put this information into complete context.

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Status of Data for 2-Methylnaphthalene

File First On-Line: 12/22/2003; Last Significant Revision: 12/22/2003

Category (section)
Last Revised
Oral RfD Assessment Yes 12/22/2003
Inhalation RfC Assessment Discussion 12/22/2003
Carcinogenicity Assessment Yes 12/22/2003
  • 2-Methylnaphthalene
  • beta-methylnaphthalene
  • 91-56-7
  • methylnaftalen
2-Methylnaphthalene Source Documents
Revision History
Date Section Description
All First IRIS RfD, cancer assessment
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect
Point of Departure*
Pulmonary alveolar proteinosis BMD05 : 4.7 mg/kg-day 1000 4 x10-3 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Information reviewed but value not estimated. See IRIS Summary.

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Carcinogenicity Assessment for Lifetime Exposure
  • Weight-of-Evidence Characterization
    • Data are inadequate for an assessment of human carcinogenic potential
  • Weight-of-Evidence Narrative:
    • Under the draft revised guidelines for carcinogen risk assessment (U.S. EPA, 1999), EPA concludes the data are inadequate for an assessment of human carcinogenic potential of 2-methylnaphthalene. Based on the absence of data concerning the carcinogenic potential of 2-methylnaphthalene in humans and limited equivocal evidence in animals.
    • This may be a synopsis of the full weight-of-evidence narrative. See IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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