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Arsine Quickview (CASRN 7784-42-1)

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

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Status of Data for Arsine

File First On-Line: 03/01/1994; Last Significant Revision: 03/01/1994

Category (section)
Last Revised
Oral RfD Assessment No
Inhalation RfC Assessment Yes 03/01/1994
Carcinogenicity Assessment No
  • 7784-42-1
  • Arsine
  • UN2188
  • Agent SA
  • Arsenic hydride
  • Arsenic hydride (AsH3)
  • Arsenic trihydride
  • Arseniuretted hydrogen
  • Arsenous hydride
  • Arsenowodor [Polish]
  • Arsenwasserstoff [German]
  • more...
Arsine Source Documents
Revision History
Date Section Description
04/01/1997 III.,IV.,V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Not Assessed under the IRIS Program.

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect
Point of Departure*
Increased hemolysis, abnormal RBC morphology, and increased spleen weight (other effect: Increased hemolysis, increased spleen weight, and impaired compensatory erythropoiesis. ) NOAEL (HEC): 1.4 x10-2 mg/m3 300 5x10-5 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

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Carcinogenicity Assessment for Lifetime Exposure

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

  • Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

  • Not Assessed under the IRIS Program.

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